Assessment of Drug Resistance during Phase 2b Clinical Trials of Presatovir in Adults Naturally Infected with Respiratory Syncytial Virus.
fusion inhibitor
presatovir
resistance
respiratory syncytial virus
Journal
Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061
Informations de publication
Date de publication:
20 08 2020
20 08 2020
Historique:
received:
26
11
2019
accepted:
12
02
2020
pubmed:
20
2
2020
medline:
22
6
2021
entrez:
20
2
2020
Statut:
epublish
Résumé
This study summarizes drug resistance analyses in 4 recent phase 2b trials of the respiratory syncytial virus (RSV) fusion inhibitor presatovir in naturally infected adults. Adult hematopoietic cell transplant (HCT) recipients, lung transplant recipients, or hospitalized patients with naturally acquired, laboratory-confirmed RSV infection were enrolled in 4 randomized, double-blind, placebo-controlled studies with study-specific presatovir dosing. Full-length RSV
Identifiants
pubmed: 32071058
pii: AAC.02312-19
doi: 10.1128/AAC.02312-19
pmc: PMC7449164
pii:
doi:
Substances chimiques
Antiviral Agents
0
Types de publication
Clinical Trial, Phase II
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2020 American Society for Microbiology.
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