Recovery from recurrent depression with mindfulness-based cognitive therapy and antidepressants: a qualitative study with illustrative case studies.
Adult
Aged
Antidepressive Agents
/ administration & dosage
Attitude
Chronic Disease
Cognitive Behavioral Therapy
/ methods
Depression
/ drug therapy
Depressive Disorder, Major
/ drug therapy
Female
General Practitioners
Humans
Male
Middle Aged
Mindfulness
Primary Health Care
Psychotherapy, Group
Qualitative Research
Quality of Life
Recurrence
Single-Blind Method
United Kingdom
antidepressants
depression & mood disorders
psychological therapy
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
18 02 2020
18 02 2020
Historique:
entrez:
21
2
2020
pubmed:
23
2
2020
medline:
17
2
2021
Statut:
epublish
Résumé
This study aimed to describe the recovery journeys of people with a history of recurrent depression who took part in a psychosocial programme designed to teach skills to prevent depressive relapse (mindfulness-based cognitive therapy (MBCT)), alongside maintenance antidepressant medication (ADM). A qualitative study embedded within a multicentre, single blind, randomised controlled trial (the PREVENT trial). Primary care urban and rural settings in the UK. 42 people who participated in the MBCT arm of the parent trial were purposively sampled to represent a range of recovery journeys. MBCT involves eight weekly group sessions, with four refresher sessions offered in the year following the end of the programme. It was adapted to offer bespoke support around ADM tapering and discontinuation. Written feedback and structured in-depth interviews were collected in the 2 years after participants undertook MBCT. Data were analysed using thematic analysis and case studies constructed to illustrate the findings. People with recurrent depression have unique recovery journeys that shape and are shaped by their pharmacological and psychological treatment choices. Their journeys typically include several over-arching themes: (1) beliefs about the causes of depression, both biological and psychosocial; (2) personal agency, including expectations about their role in recovery and treatment; (3) acceptance, both of depression itself and the recovery journey; (4) quality of life; (5) experiences and perspectives on ADM and ADM tapering-discontinuation; and (6) the role of general practitioners, both positive and negative. People with recurrent depression describe unique, complex recovery journeys shaped by their experiences of depression, treatment and interactions with health professionals. Understanding how several themes coalesce for each individual can both support their recovery and treatment choices as well as health professionals in providing more accessible, collaborative, individualised and empowering care. Clinical trial number ISRCTN26666654; post results.
Identifiants
pubmed: 32075835
pii: bmjopen-2019-033892
doi: 10.1136/bmjopen-2019-033892
pmc: PMC7044862
doi:
Substances chimiques
Antidepressive Agents
0
Banques de données
ISRCTN
['ISRCTN26666654']
Types de publication
Case Reports
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e033892Subventions
Organisme : Wellcome Trust
ID : 107496/Z/15/Z
Pays : United Kingdom
Informations de copyright
© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
Lancet Psychiatry. 2018 May;5(5):401-410
pubmed: 29625762
Eur J Epidemiol. 2005;20(1):103-11
pubmed: 15756910
Trials. 2014 Jun 10;15:217
pubmed: 24916319
Trials. 2010 Oct 20;11:99
pubmed: 20961444
J Affect Disord. 2019 Feb 15;245:38-62
pubmed: 30366236
Ann Fam Med. 2019 Jan;17(1):52-60
pubmed: 30670397
Soc Sci Med. 2015 Dec;146:53-61
pubmed: 26498732
Annu Rev Public Health. 2013;34:119-38
pubmed: 23514317
JAMA Psychiatry. 2016 Jun 1;73(6):565-74
pubmed: 27119968
Br J Med Psychol. 1992 Sep;65 ( Pt 3):257-68
pubmed: 1390360
Health Technol Assess. 2015 Sep;19(73):1-124
pubmed: 26379122
Curr Psychiatry Rep. 2019 Nov 23;21(12):129
pubmed: 31760505
Science. 1977 Apr 8;196(4286):129-36
pubmed: 847460
Lancet. 2018 Nov 10;392(10159):1789-1858
pubmed: 30496104
Clin Psychol Rev. 2015 Nov;41:16-26
pubmed: 25754289
Behav Cogn Psychother. 2009 Jul;37(4):413-30
pubmed: 19508744
Br J Gen Pract. 2016 Oct;66(651):e708-19
pubmed: 27528709
J Psychoactive Drugs. 2013 Nov-Dec;45(5):409-15
pubmed: 24592667
Soc Sci Med. 2009 Jan;68(1):154-68
pubmed: 19013702
Lancet. 2015 Jul 4;386(9988):63-73
pubmed: 25907157