Recovery from recurrent depression with mindfulness-based cognitive therapy and antidepressants: a qualitative study with illustrative case studies.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
18 02 2020
Historique:
entrez: 21 2 2020
pubmed: 23 2 2020
medline: 17 2 2021
Statut: epublish

Résumé

This study aimed to describe the recovery journeys of people with a history of recurrent depression who took part in a psychosocial programme designed to teach skills to prevent depressive relapse (mindfulness-based cognitive therapy (MBCT)), alongside maintenance antidepressant medication (ADM). A qualitative study embedded within a multicentre, single blind, randomised controlled trial (the PREVENT trial). Primary care urban and rural settings in the UK. 42 people who participated in the MBCT arm of the parent trial were purposively sampled to represent a range of recovery journeys. MBCT involves eight weekly group sessions, with four refresher sessions offered in the year following the end of the programme. It was adapted to offer bespoke support around ADM tapering and discontinuation. Written feedback and structured in-depth interviews were collected in the 2 years after participants undertook MBCT. Data were analysed using thematic analysis and case studies constructed to illustrate the findings. People with recurrent depression have unique recovery journeys that shape and are shaped by their pharmacological and psychological treatment choices. Their journeys typically include several over-arching themes: (1) beliefs about the causes of depression, both biological and psychosocial; (2) personal agency, including expectations about their role in recovery and treatment; (3) acceptance, both of depression itself and the recovery journey; (4) quality of life; (5) experiences and perspectives on ADM and ADM tapering-discontinuation; and (6) the role of general practitioners, both positive and negative. People with recurrent depression describe unique, complex recovery journeys shaped by their experiences of depression, treatment and interactions with health professionals. Understanding how several themes coalesce for each individual can both support their recovery and treatment choices as well as health professionals in providing more accessible, collaborative, individualised and empowering care. Clinical trial number ISRCTN26666654; post results.

Identifiants

pubmed: 32075835
pii: bmjopen-2019-033892
doi: 10.1136/bmjopen-2019-033892
pmc: PMC7044862
doi:

Substances chimiques

Antidepressive Agents 0

Banques de données

ISRCTN
['ISRCTN26666654']

Types de publication

Case Reports Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e033892

Subventions

Organisme : Wellcome Trust
ID : 107496/Z/15/Z
Pays : United Kingdom

Informations de copyright

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Alice Tickell (A)

Department of Psychiatry, University of Oxford, Oxford, UK.

Richard Byng (R)

Peninsula Medical School, Faculty of Health, University of Plymouth, Plymouth, UK.

Catherine Crane (C)

Department of Psychiatry, University of Oxford, Oxford, UK.

Felix Gradinger (F)

Peninsula Medical School, Faculty of Health, University of Plymouth, Plymouth, UK.

Rachel Hayes (R)

Department of Psychiatry, University of Oxford, Oxford, UK.

James Robson (J)

Department of Education, University of Oxford, Oxford, UK.

Jessica Cardy (J)

Department of Psychiatry, University of Oxford, Oxford, UK.

Alice Weaver (A)

Department of Psychiatry, University of Oxford, Oxford, UK.

Nicola Morant (N)

Department of Psychiatry, University College London, London, UK.

Willem Kuyken (W)

Department of Psychiatry, University of Oxford, Oxford, UK willem.kuyken@psych.ox.ac.uk.

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Classifications MeSH