Caveolae in CNS arterioles mediate neurovascular coupling.
Animals
Arterioles
/ cytology
Caveolae
/ metabolism
Central Nervous System
/ cytology
Cerebral Cortex
/ cytology
Endothelial Cells
/ metabolism
Female
Male
Mice
Microscopy, Fluorescence, Multiphoton
Neurovascular Coupling
Nitric Oxide Synthase Type III
/ deficiency
Vasodilation
Vibrissae
/ physiology
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
19
02
2019
accepted:
03
01
2020
pubmed:
23
2
2020
medline:
14
4
2020
entrez:
21
2
2020
Statut:
ppublish
Résumé
Proper brain function depends on neurovascular coupling: neural activity rapidly increases local blood flow to meet moment-to-moment changes in regional brain energy demand
Identifiants
pubmed: 32076269
doi: 10.1038/s41586-020-2026-1
pii: 10.1038/s41586-020-2026-1
pmc: PMC7060132
mid: NIHMS1548198
doi:
Substances chimiques
Nitric Oxide Synthase Type III
EC 1.14.13.39
Nos3 protein, mouse
EC 1.14.13.39
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
106-110Subventions
Organisme : NINDS NIH HHS
ID : DP1 NS092473
Pays : United States
Organisme : NINDS NIH HHS
ID : R37 NS046579
Pays : United States
Organisme : NINDS NIH HHS
ID : P30 NS072030
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States
Organisme : NINDS NIH HHS
ID : K99 NS102429
Pays : United States
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