Myelin Oligodendrocyte Glycoprotein Antibody (MOG-IgG)-Positive Optic Perineuritis.
Optic perineuritis
aquaporin-4 (AQP4)
myelin oligodendrocyte glycoprotein (MOG)
optic nerve sheath
optic neuritis
Journal
Neuro-ophthalmology (Aeolus Press)
ISSN: 0165-8107
Titre abrégé: Neuroophthalmology
Pays: England
ID NLM: 8408966
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
received:
05
03
2019
revised:
04
04
2019
accepted:
11
04
2019
pmc-release:
28
05
2020
entrez:
21
2
2020
pubmed:
23
2
2020
medline:
23
2
2020
Statut:
epublish
Résumé
Optic perineuritis can be a manifestation of infectious and systemic inflammatory disorders, but the majority of cases are idiopathic. Myelin oligodendrocyte glycoprotein (MOG)-IgG-positive optic neuritis has been reported to be associated with optic nerve sheath enhancement. This report describes two MOG-IgG patients with clinical, radiological and therapeutic response consistent with optic perineuritis. MOG-IgG may account for many cases of previously described idiopathic optic perineuritis. Vision loss with optic nerve sheath enhancement on MRI should prompt testing for MOG-IgG.
Identifiants
pubmed: 32076441
doi: 10.1080/01658107.2019.1607883
pii: 1607883
pmc: PMC6999618
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1-4Informations de copyright
© 2019 Taylor & Francis Group, LLC.
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