Application of Antibiotics/Antimicrobial Agents on Dental Caries.


Journal

BioMed research international
ISSN: 2314-6141
Titre abrégé: Biomed Res Int
Pays: United States
ID NLM: 101600173

Informations de publication

Date de publication:
2020
Historique:
received: 16 10 2019
accepted: 13 12 2019
entrez: 21 2 2020
pubmed: 23 2 2020
medline: 1 12 2020
Statut: epublish

Résumé

Dental caries is the most common oral disease. The bacteriological aetiology of dental caries promotes the use of antibiotics or antimicrobial agents to prevent this type of oral infectious disease. Antibiotics have been developed for more than 80 years since Fleming discovered penicillin in 1928, and systemic antibiotics have been used to treat dental caries for a long time. However, new types of antimicrobial agents have been developed to fight against dental caries. The purpose of this review is to focus on the application of systemic antibiotics and other antimicrobial agents with respect to their clinical use to date, including the history of their development, and their side effects, uses, structure types, and molecular mechanisms to promote a better understanding of the importance of microbial interactions in dental plaque and combinational treatments.

Identifiants

pubmed: 32076608
doi: 10.1155/2020/5658212
pmc: PMC7013294
doi:

Substances chimiques

Anti-Bacterial Agents 0
Anti-Infective Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

5658212

Informations de copyright

Copyright © 2020 Wei Qiu et al.

Déclaration de conflit d'intérêts

The authors confirm that this article content has no conflicts of interest.

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Auteurs

Wei Qiu (W)

Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
State Key Laboratory of Oral Disease, West China Hospital of Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu 610064, China.

Yujie Zhou (Y)

State Key Laboratory of Oral Disease, West China Hospital of Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu 610064, China.
Department of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

Zixin Li (Z)

West China School of Stomatology, Sichuan University, Chengdu 610041, China.

Tu Huang (T)

West China School of Stomatology, Sichuan University, Chengdu 610041, China.

Yuhan Xiao (Y)

West China School of Stomatology, Sichuan University, Chengdu 610041, China.

Lei Cheng (L)

State Key Laboratory of Oral Disease, West China Hospital of Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu 610064, China.

Xian Peng (X)

State Key Laboratory of Oral Disease, West China Hospital of Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu 610064, China.

Lixin Zhang (L)

Chinese Academy of Sciences Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
State Key Laboratory of Bioreactor Engineering, East China University of Science & Technology, Shanghai 200237, China.

Biao Ren (B)

State Key Laboratory of Oral Disease, West China Hospital of Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu 610064, China.

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