Dose indicator for CyberKnife image-guided radiation therapy.
CyberKnife
IGRT
effective dose
organ dose
risk
Journal
Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
15
10
2019
revised:
14
02
2020
accepted:
14
02
2020
pubmed:
23
2
2020
medline:
2
3
2021
entrez:
21
2
2020
Statut:
ppublish
Résumé
The purpose of this study was to calculate dose distributions from CyberKnife image-guided radiation therapy (IGRT) for brain, H&N, lung, and pelvis treatment regions and use them to extract the corresponding effective dose and estimate-related risk. We developed a CyberKnife IGRT kV beam model in a standard treatment planning system and validated it against measurements in heterogeneous phantoms. Five brain, five head and neck, five thorax, and 10 (five male and five female) pelvis patient computed tomographies (CTs) were contoured. The dose distribution resulting from different CyberKnife IGRT protocols was calculated. From them, the effective dose was calculated according to ICRP publication Nr 103, using the average dose to contoured organs. The corresponding risk factors were calculated. Entrance surface dose (ESD) was also calculated and compared with existing data. The maximum effective dose produced by CyberKnife IGRT protocols was 0.8 mSv (brain), 1.9 mSv (H&N), 20.2 (pelvis), and 42.4 mSv (thorax) per fraction for a risk estimate of 0.004% (brain), 0.01% (H&N), 0.1% (pelvis), and 0.2% (thorax). Calculated ESD were compatible with existing data. Dose calculation models for CyberKnife IGRT kV beams were implemented in a clinical treatment planning system and validated in water and heterogeneous phantoms. We determined the effective dose and the related risk estimate resulting from CyberKnife IGRT protocols for brain, head and neck, thorax, and pelvis cases. The effective doses calculated for CyberKnife IGRT protocols were similar to those obtained for cone beam CT protocols on conventional C-arm linear accelerators, except for extreme irradiation conditions for thorax cases (140 kV X-ray tube tension).
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2309-2316Subventions
Organisme : Swiss Federal Office of Public Health
ID : 15.017754
Informations de copyright
© 2020 American Association of Physicists in Medicine.
Références
Alaei P, Ding G, Guan H. Inclusion of the dose from kilovoltage cone beam CT in the radiation therapy treatment plans. Med Phys. 2010;37:244-248.
Alaei P, Gerbi BJ, Geise RA. Evaluation of a model-based treatment planning system for dose computations in the kilovoltage energy range. Med Phys. 2000;27:2821-2826.
Alaei P, Gerbi BJ, Geise RA. Lung dose calculations at kilovoltage x-ray energies using a model-based treatment planning system. Med Phys. 2001;28:194-198.
Alaei P, Spezi E. Imaging dose from cone beam computed tomography in radiation therapy. Physica Medica. 2015;31:647-658.
Dzierma Y, Nuesken F, Otto W, Alaei P, Licht N, Rübe C. Dosimetry of an in-line kilovoltage imaging system and implementation in treatment planning. Int J Radiat Oncol Biol Phys. 2013;88:913-919.
Adler JR Jr, Chang SD, Murphy MJ, Doty J, Geis P, Hancock SL. The cyberknife: a frameless robotic system for radiosurgery. Stereot Funct Neurosurg. 1997;69:124-128.
Guo Y, Zhuang H, Zhao L, Yuan Z, Wang P. Influence of different image-guided tracking methods upon the local efficacy of CyberKnife treatment in lung tumors. Thor Cancer. 2015;6:255-259.
Murphy MJ, Balter J, Balter S, et al. The management of imaging dose during image-guided radiotherapy: report of the AAPM Task Group 75. Med Phys. 2007;34:4041-4063.
Dieterich S, Cavedon C, Chuang CF, et al. Report of AAPM TG 135: quality assurance for robotic radiosurgery. Med Phys. 2011;38:2914-2936.
Kilby W, Dooley JR, Kuduvalli G, Sayeh S, Maurer CR. The CyberKnife® robotic radiosurgery system in 2010. Technol Cancer Res Treatm. 2010;9:433-452.
Pepin EW, Wu H, Zhang Y, Lord B. Correlation and prediction uncertainties in the CyberKnife Synchrony respiratory tracking system. Med Phys. 2011;38:4036-4044.
Alaei P, Gerbi BJ, Geise RA. Generation and use of photon energy deposition kernels for diagnostic quality x rays. Med Phys. 1999;26:1687-1697.
ICRP. 2007 recommendations of the International Commission on Radiological Protection. ICRP Publication 103, Annals of ICRP, 32; 2007.
Conrad M, Bolard G, Nowak M, et al. Determination of the effective dose delivered by image guided radiotherapy in head & neck and breast treatments. Zeitschrift für Medizinische Physik. 2018;28:276-285.
ICRP. Basic anatomical and physiological data for use in radiological protection: reference values. ICRP Publication 89, Annals of ICRP, 32; 2002.
ICRP. Basic anatomical and physiological data for use in radiological protection: The skeleton. ICRP Publication 70, Annals of ICRP, 32; 1995.
SSRMP. Quality control of gantry-mounted image-guided radiotherapy systems. Recommendations Nr 16, ISBN 3 908 125 48 0, Swiss Society of Radiobiology and Medical Physics; 2010.
Fontenot JD, Alkhatib H, Garrett JA, et al. AAPM Medical Physics Practice Guideline 2.a: Commissioning and quality assurance of X-ray-based image-guided radiotherapy systems. J Appl Clin Med Phys. 2014;15:3-13.
Stelczer G, Tatai-Szabó D, Major T, et al. Measurement of dose exposure of image guidance in external beam accelerated partial breast irradiation: evaluation of different techniques and linear accelerators. Physica Medica. 2019;63:70-78.
Nobah A, Aldelaijan S, Devic S, et al. Radiochromic film based dosimetry of image-guidance procedures on different radiotherapy modalities. J Appl Clin Med Phys. 2014;15:229-239.
Canbolat A, Zorlu F, Hurmuz P, Yeginer M, Ozyigit G. Investigating the surface dose contribution of intrafractional kV imaging in CyberKnife-based stereotactic radiosurgery. Med Dosimetry. 2017. https://doi.org/10.1016/j.meddos.2017.06.005
Alaei P, Spezi E. Commissioning kilovoltage cone-beam CT beams in a radiation therapy treatment planning system. J Appl Clin Med Phys. 2012;13:19-33.