Genome-Scale Metabolic Reconstruction and

arctic flux balance analysis gene deletion metabolic network reaction deletion systems biology

Journal

Biology
ISSN: 2079-7737
Titre abrégé: Biology (Basel)
Pays: Switzerland
ID NLM: 101587988

Informations de publication

Date de publication:
17 Feb 2020
Historique:
received: 15 12 2019
revised: 31 01 2020
accepted: 08 02 2020
entrez: 22 2 2020
pubmed: 23 2 2020
medline: 23 2 2020
Statut: epublish

Résumé

Diatoms are major primary producers in polar environments where they can actively grow under extremely variable conditions. Integrative modeling using a genome-scale model (GSM) is a powerful approach to decipher the complex interactions between components of diatom metabolism and can provide insights into metabolic mechanisms underlying their evolutionary success in polar ecosystems. We developed the first GSM for a polar diatom,

Identifiants

pubmed: 32079178
pii: biology9020030
doi: 10.3390/biology9020030
pmc: PMC7168318
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Sentinel North postdoctoral fellowship
ID : No grant number

Références

Nat Protoc. 2010 Jan;5(1):93-121
pubmed: 20057383
New Phytol. 2015 Jan;205(1):172-81
pubmed: 25283055
PLoS Comput Biol. 2017 Sep 8;13(9):e1005728
pubmed: 28886026
Microbiol Mol Biol Rev. 2006 Mar;70(1):222-52
pubmed: 16524924
Biology (Basel). 2014 Jan 28;3(1):56-80
pubmed: 24833335
Nature. 2002 Nov 14;420(6912):186-9
pubmed: 12432395
Nat Protoc. 2019 Mar;14(3):639-702
pubmed: 30787451
J Phycol. 2016 Apr;52(2):239-51
pubmed: 27037589
J Theor Biol. 2008 Jun 7;252(3):433-41
pubmed: 18023456
Biosystems. 2012 Aug;109(2):233-9
pubmed: 22446067
Mol Syst Biol. 2010 Jul;6:390
pubmed: 20664636
Ann Rev Mar Sci. 2014;6:439-67
pubmed: 24015900
New Phytol. 2015 Jan;205(1):182-91
pubmed: 25382393
Nat Biotechnol. 2010 Mar;28(3):245-8
pubmed: 20212490
New Phytol. 2019 May;222(3):1364-1379
pubmed: 30636322
Nat Rev Genet. 2008 Nov;9(11):855-67
pubmed: 18852697
Nat Rev Genet. 2018 Jan;19(1):34-49
pubmed: 29033457
Sci Data. 2017 Oct 10;4:170149
pubmed: 28994819
Nature. 2015 Aug 20;524(7565):366-9
pubmed: 26168400
Plant Physiol. 2016 Sep;172(1):589-602
pubmed: 27372244
Plant J. 2016 Jan;85(1):161-76
pubmed: 26590126
New Phytol. 2019 Jul;223(2):675-691
pubmed: 30985935
Nat Genet. 2006 Sep;38(9):993-8
pubmed: 16941010
Metab Eng. 2019 Mar;52:42-56
pubmed: 30439494
Nature. 2004 Jun 10;429(6992):661-4
pubmed: 15190353
Wiley Interdiscip Rev Syst Biol Med. 2010 May-Jun;2(3):372-382
pubmed: 20836035
Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15112-7
pubmed: 12415116
Nature. 2017 Jan 26;541(7638):536-540
pubmed: 28092920
Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2307-12
pubmed: 17284612
PLoS One. 2016 May 06;11(5):e0155038
pubmed: 27152931
Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):412-7
pubmed: 25548193

Auteurs

Michel Lavoie (M)

Unité Mixte Internationale 3376 Takuvik, CNRS-ULaval, Département de Biologie and Québec-Océan, Université Laval, Québec, QC G1V 0A6, Canada.

Blanche Saint-Béat (B)

Unité Mixte Internationale 3376 Takuvik, CNRS-ULaval, Département de Biologie and Québec-Océan, Université Laval, Québec, QC G1V 0A6, Canada.

Jan Strauss (J)

Department of Biology, University of Hamburg, D-22607 Hamburg, Germany.
CSSB Centre for Structural Systems Biology, c/o Deutsches Elektronen-Synchrotron DESY, Notkestraße 85, D-22607 Hamburg, Germany.

Sébastien Guérin (S)

Unité Mixte Internationale 3376 Takuvik, CNRS-ULaval, Département de Biologie and Québec-Océan, Université Laval, Québec, QC G1V 0A6, Canada.

Antoine Allard (A)

Département de physique, de génie physique et d'optique, Université Laval, Québec, QC G1V 0A6, Canada.
Centre interdisciplinaire de modélisation mathématique, Université Laval, Québec, QC G1V 0A6, Canada.

Simon V Hardy (S)

Département d'informatique et génie logiciel, Département de biochimie, microbiologie et bio-informatique, Université Laval, Québec, QC G1V 0A6, Canada.
Unité des Neurosciences cellulaires et moléculaires, Centre de recherche CERVO, Québec, QC G1V 0A6, Canada.

Angela Falciatore (A)

Institut de Biologie Physico-Chimique, Laboratory of Chloroplast Biology and Light Sensing in Microalgae, UMR7141, Centre National de la Recherche Scientifique (CNRS), Sorbonne Université, 75005 Paris, France.

Johann Lavaud (J)

Unité Mixte Internationale 3376 Takuvik, CNRS-ULaval, Département de Biologie and Québec-Océan, Université Laval, Québec, QC G1V 0A6, Canada.

Classifications MeSH