AstroDot - a new method for studying the spatial distribution of mRNA in astrocytes.

Alzheimer Disease Animals Astrocytes Glial Fibrillary Acidic Protein / genetics Mice Microglia RNA, Messenger / genetics
APPswe/PS1dE9 mouse Alzheimer's disease Astrocytes GFAP Hippocampus ImageJ Immunofluorescence In situ hybridization Microglia mRNA

Journal

Journal of cell science
ISSN: 1477-9137
Titre abrégé: J Cell Sci
Pays: England
ID NLM: 0052457

Informations de publication

Date de publication:
08 04 2020
Historique:
received: 27 09 2019
accepted: 09 02 2020
pubmed: 23 2 2020
medline: 22 6 2021
entrez: 22 2 2020
Statut: epublish

Résumé

Astrocytes are morphologically complex and use local translation to regulate distal functions. To study the distribution of mRNA in astrocytes, we combined mRNA detection via

Identifiants

DOI: 10.1242/jcs.239756 PMID: 32079659
pubmed: 32079659
pii: jcs.239756
doi: 10.1242/jcs.239756
pii:
doi:

Substances chimiques

Glial Fibrillary Acidic Protein 0
RNA, Messenger 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2020. Published by The Company of Biologists Ltd.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare no competing or financial interests.

Auteurs

Marc Oudart (M)

Physiology and Physiopathology of the Gliovascular Unit Research Group, Center for Interdisciplinary Research in Biology (CIRB), College de France, CNRS Unité Mixte de Recherche 724, INSERM Unité 1050, Labex Memolife, PSL Research University, Paris 75005, France.
Center for Interdisciplinary Research in Biology (CIRB), College de France, Unité Mixte de Recherche 7241 CNRS, Unité1050 INSERM, PSL Research University, Paris 75005, France.

Romain Tortuyaux (R)

Physiology and Physiopathology of the Gliovascular Unit Research Group, Center for Interdisciplinary Research in Biology (CIRB), College de France, CNRS Unité Mixte de Recherche 724, INSERM Unité 1050, Labex Memolife, PSL Research University, Paris 75005, France.
Center for Interdisciplinary Research in Biology (CIRB), College de France, Unité Mixte de Recherche 7241 CNRS, Unité1050 INSERM, PSL Research University, Paris 75005, France.
ORCID: 0000-0002-4182-6023

Philippe Mailly (P)

Center for Interdisciplinary Research in Biology (CIRB), College de France, Unité Mixte de Recherche 7241 CNRS, Unité1050 INSERM, PSL Research University, Paris 75005, France.
Orion Imaging Facility, Center for Interdisciplinary Research in Biology (CIRB), College de France, CNRS Unité Mixte de Recherche 724, INSERM Unité 1050, Labex Memolife, PSL Research University, Paris 75005, France.

Noémie Mazaré (N)

Physiology and Physiopathology of the Gliovascular Unit Research Group, Center for Interdisciplinary Research in Biology (CIRB), College de France, CNRS Unité Mixte de Recherche 724, INSERM Unité 1050, Labex Memolife, PSL Research University, Paris 75005, France.
Center for Interdisciplinary Research in Biology (CIRB), College de France, Unité Mixte de Recherche 7241 CNRS, Unité1050 INSERM, PSL Research University, Paris 75005, France.
ORCID: 0000-0003-4073-8811

Anne-Cécile Boulay (AC)

Physiology and Physiopathology of the Gliovascular Unit Research Group, Center for Interdisciplinary Research in Biology (CIRB), College de France, CNRS Unité Mixte de Recherche 724, INSERM Unité 1050, Labex Memolife, PSL Research University, Paris 75005, France.
Center for Interdisciplinary Research in Biology (CIRB), College de France, Unité Mixte de Recherche 7241 CNRS, Unité1050 INSERM, PSL Research University, Paris 75005, France.
ORCID: 0000-0001-5620-6209

Martine Cohen-Salmon (M)

Physiology and Physiopathology of the Gliovascular Unit Research Group, Center for Interdisciplinary Research in Biology (CIRB), College de France, CNRS Unité Mixte de Recherche 724, INSERM Unité 1050, Labex Memolife, PSL Research University, Paris 75005, France martine.cohen-salmon@college-de-france.fr.
Center for Interdisciplinary Research in Biology (CIRB), College de France, Unité Mixte de Recherche 7241 CNRS, Unité1050 INSERM, PSL Research University, Paris 75005, France.
ORCID: 0000-0002-5312-8476

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Classifications MeSH

questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Démence › Maladie d'Alzheimer › AstroDot - a new method for studying the...
questionsmedicales.fr › Eucaryotes › Animaux › AstroDot - a new method for studying the...
questionsmedicales.fr › Cellules › Névroglie › Astrocytes › AstroDot - a new method for studying the...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du cytosquelette › Protéines de filaments intermédiaires › Protéine gliofibrillaire acide › AstroDot - a new method for studying the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › AstroDot - a new method for studying the...
questionsmedicales.fr › Cellules › Névroglie › Microglie › AstroDot - a new method for studying the...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN messager › AstroDot - a new method for studying the...