Intraconal Metastasis Leading to Diagnosis of Hepatocellular Carcinoma.
Hepatocellular carcinoma
Imaging
Intraconal metastasis
Sorafenib
Journal
Middle East journal of digestive diseases
ISSN: 2008-5230
Titre abrégé: Middle East J Dig Dis
Pays: Iran
ID NLM: 101535395
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
entrez:
22
2
2020
pubmed:
23
2
2020
medline:
23
2
2020
Statut:
ppublish
Résumé
Hepatocellular carcinoma (HCC) is the commontumor of the liver and the third most common cause of cancer-related mortality worldwide. Patients with HCC may have metastasis to different sites. Intrahepatic and extrahepatic metastases are found in (~50-75%). Lung and regional lymph nodes are the most commonly involved sites. Metastasis to bone, skin, and adrenal glands are rare. Orbit metastasis and intracranial invasion are extremely rare. We are presenting a case of HCC that metastasized to the orbital cavity. The patient presented with progressive proptosis of the eyeball with retrobulbar and intracranial invasion and involvement of the sub-scalp region. Based on the imaging findings, it was initially misdiagnosed as meningioma; however, histopathological examination of the biopsy specimen resulted in a definitive diagnosis of HCC metastasis. The present case reveals that the alternative diagnosis of metastasis must be considered when diagnosing retrobulbar lesions in patients with HCC.
Identifiants
pubmed: 32082522
doi: 10.15171/mejdd.2020.164
pmc: PMC7023650
doi:
Types de publication
Case Reports
Langues
eng
Pagination
48-51Informations de copyright
© 2020 The Author(s).
Déclaration de conflit d'intérêts
CONFLICT OF INTEREST The authors declare no conflict of interest related to this work.
Références
Gastroenterol Hepatol Bed Bench. 2014 Summer;7(3):177-82
pubmed: 25120900
Am J Ophthalmol. 1967 Apr;63(4):727-32
pubmed: 6022245
Ophthalmology. 1990 May;97(5):620-4
pubmed: 2342807
Cancer. 2009 Nov 1;115(21):4895-906
pubmed: 19637355
Orbit. 2009;28(2-3):153-9
pubmed: 19839900
Arch Ophthalmol. 1971 Jun;85(6):673-5
pubmed: 5562786
Graefes Arch Clin Exp Ophthalmol. 2011 Sep;249(9):1387-93
pubmed: 21468734
Curr Opin Ophthalmol. 2007 Sep;18(5):405-13
pubmed: 17700235
Arch Ophthalmol. 1979 Jul;97(7):1315-7
pubmed: 454270
Surv Ophthalmol. 1990 Jul-Aug;35(1):1-24
pubmed: 2204127
CA Cancer J Clin. 2005 Mar-Apr;55(2):74-108
pubmed: 15761078