Problem solving in clinical practice: the sick infant with low sodium and high potassium.

aldosterone congenital adrenal hyperplasia hyperkalaemia hyponatraemia neonatology

Journal

Archives of disease in childhood. Education and practice edition
ISSN: 1743-0593
Titre abrégé: Arch Dis Child Educ Pract Ed
Pays: England
ID NLM: 101220684

Informations de publication

Date de publication:
02 2021
Historique:
received: 21 06 2019
revised: 22 01 2020
accepted: 05 02 2020
pubmed: 23 2 2020
medline: 16 11 2021
entrez: 23 2 2020
Statut: ppublish

Résumé

Many paediatricians will be faced with a sick infant who on investigation is found to have hyponatraemia and hyperkalaemia at some time in their career. The focus of initial management includes the treatment of potentially life-threatening hyperkalaemia with concurrent investigation aiming to elucidate whether the underlying cause reflects a primarily renal or endocrine pathology. We describe the presentation of two infants who each presented with one of the more common underlying diagnoses that led to this biochemical disturbance and discuss the approach to immediate treatment, diagnostic work-up and longer term management.

Identifiants

pubmed: 32086340
pii: archdischild-2019-317756
doi: 10.1136/archdischild-2019-317756
doi:

Substances chimiques

Sodium 9NEZ333N27
Potassium RWP5GA015D

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

23-27

Informations de copyright

© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Yincent Tse (Y)

Department of Paediatric Nephrology, Great North Children's Hospital, Newcastle upon Tyne, UK yincenttse@nhs.net.
Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.

Nidhi Singhal (N)

Department of Paediatric Nephrology, Great North Children's Hospital, Newcastle upon Tyne, UK.

Leigh McDonald (L)

Department of Radiology, Great North Children's Hospital, Newcastle upon Tyne, UK.

Milan Gopal (M)

Department of Paediatric Urology, Great North Children's Hospital, Newcastle upon Tyne, UK.

Anupam Lall (A)

Department of Paediatric Urology, Great North Children's Hospital, Newcastle upon Tyne, UK.

Helen Johnstone (H)

Department of Paediatric Endocrinology, Great North Childrens Hospital, Newcastle upon Tyne, UK.

Timothy Cheetham (T)

Translational and Clinical Research Institute, Newcastle University c/o Department of Paediatric Endocrinology, Great North Children's Hospital, Newcastle upon Tyne, UK.

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Classifications MeSH