Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I.


Journal

The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R

Informations de publication

Date de publication:
03 04 2020
Historique:
received: 15 11 2019
revised: 14 02 2020
pubmed: 23 2 2020
medline: 30 12 2020
entrez: 23 2 2020
Statut: ppublish

Résumé

Heart muscle contractility and performance are controlled by posttranslational modifications of sarcomeric proteins. Although myosin regulatory light chain (RLC) phosphorylation has been studied extensively

Identifiants

pubmed: 32086378
pii: S0021-9258(17)48707-2
doi: 10.1074/jbc.RA119.011945
pmc: PMC7135997
doi:

Substances chimiques

Myosin Light Chains 0
Peptides 0
Recombinant Proteins 0
Troponin I 0
Myosin-Light-Chain Kinase EC 2.7.11.18
Calcium SY7Q814VUP

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4398-4410

Subventions

Organisme : British Heart Foundation
ID : FS/16/3/31887
Pays : United Kingdom
Organisme : British Heart Foundation
ID : PG/16/19/32072
Pays : United Kingdom
Organisme : British Heart Foundation
ID : FS/15/1/31071
Pays : United Kingdom
Organisme : British Heart Foundation
ID : CH/08/001
Pays : United Kingdom
Organisme : British Heart Foundation
ID : FS/15/1/31071
Pays : United Kingdom
Organisme : Medical Research Council
ID : G0200496
Pays : United Kingdom
Organisme : British Heart Foundation
ID : CH/08/001/25300
Pays : United Kingdom
Organisme : British Heart Foundation
ID : FS/16/3/31887
Pays : United Kingdom

Informations de copyright

© 2020 Sevrieva et al.

Références

J Mol Cell Cardiol. 2018 Dec;125:140-148
pubmed: 30359561
Sci Rep. 2017 Dec 13;7(1):17495
pubmed: 29235529
J Biol Chem. 1994 Nov 11;269(45):28173-80
pubmed: 7961753
J Physiol. 2009 Jan 15;587(1):155-63
pubmed: 19015190
J Mol Cell Cardiol. 2018 Aug;121:81-93
pubmed: 29981798
Proteomics Clin Appl. 2009 Dec;3(12):1371-82
pubmed: 21136957
J Biol Chem. 1994 Oct 7;269(40):24723-7
pubmed: 7929147
J Physiol. 2018 Jan 1;596(1):31-46
pubmed: 29052230
Proc Natl Acad Sci U S A. 1986 May;83(10):3542-6
pubmed: 2939452
J Biol Chem. 2008 Jul 11;283(28):19748-56
pubmed: 18474588
J Biol Chem. 1999 Jul 23;274(30):21085-94
pubmed: 10409661
J Mol Cell Cardiol. 2007 Jan;42(1):247-59
pubmed: 17081561
ESC Heart Fail. 2019 Apr;6(2):406-415
pubmed: 30690923
Circ Res. 1995 Jun;76(6):1028-35
pubmed: 7758157
Circ Res. 2008 Mar 14;102(5):571-80
pubmed: 18202317
Prog Biophys Mol Biol. 2008 Jun-Jul;97(2-3):250-67
pubmed: 18466959
Arch Biochem Biophys. 2011 Jun 15;510(2):129-34
pubmed: 21345328
Cardiovasc Res. 2003 Jan;57(1):37-47
pubmed: 12504812
J Clin Invest. 2007 Oct;117(10):2812-24
pubmed: 17885681
Biochem Res Int. 2012;2012:290971
pubmed: 22649731
J Biol Chem. 2001 Feb 16;276(7):4527-30
pubmed: 11096123
J Biol Chem. 1992 Dec 25;267(36):25945-50
pubmed: 1464607
J Physiol. 2010 Mar 15;588(Pt 6):981-93
pubmed: 20123786
Circ Res. 2012 Aug 3;111(4):482-92
pubmed: 22859670
Am J Physiol Renal Physiol. 2020 Mar 1;318(3):F600-F616
pubmed: 31904282
Circ Res. 2013 Jan 18;112(2):355-66
pubmed: 23329791
J Biol Chem. 2015 Apr 24;290(17):10703-16
pubmed: 25733667
J Mol Cell Cardiol. 2015 Aug;85:199-206
pubmed: 26057075
J Biol Chem. 2018 Jun 1;293(22):8588-8599
pubmed: 29669813
J Biol Chem. 1995 Dec 22;270(51):30773-80
pubmed: 8530519
EMBO J. 2011 May 10;30(12):2477-89
pubmed: 21556048
J Mol Cell Cardiol. 2010 May;48(5):1023-8
pubmed: 20298699
Proc Natl Acad Sci U S A. 2016 May 24;113(21):E3039-47
pubmed: 27162358
Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4138-46
pubmed: 26124132
Physiol Rev. 2000 Apr;80(2):853-924
pubmed: 10747208
Life Sci. 2018 Dec 15;215:119-127
pubmed: 30399377
Science. 1991 Jul 26;253(5018):414-20
pubmed: 1862343
Eur J Biochem. 1997 Sep 1;248(2):329-37
pubmed: 9346285
Arch Biochem Biophys. 2016 Jul 1;601:56-68
pubmed: 26763941
Circulation. 2012 Nov 27;126(22):2575-88
pubmed: 23095280
J Clin Invest. 2012 Apr;122(4):1209-21
pubmed: 22426213
J Biol Chem. 2010 Dec 24;285(52):40819-29
pubmed: 20943660
J Biol Chem. 2009 Feb 20;284(8):5097-106
pubmed: 19106098
Cardiovasc Res. 2008 Dec 1;80(3):407-15
pubmed: 18703533

Auteurs

Ivanka R Sevrieva (IR)

Randall Centre for Cell and Molecular Biophysics and British Heart Foundation Centre of Research Excellence, King's College London, London SE1 1UL, United Kingdom.

Birgit Brandmeier (B)

Randall Centre for Cell and Molecular Biophysics and British Heart Foundation Centre of Research Excellence, King's College London, London SE1 1UL, United Kingdom.

Saraswathi Ponnam (S)

Randall Centre for Cell and Molecular Biophysics and British Heart Foundation Centre of Research Excellence, King's College London, London SE1 1UL, United Kingdom.

Mathias Gautel (M)

Randall Centre for Cell and Molecular Biophysics and British Heart Foundation Centre of Research Excellence, King's College London, London SE1 1UL, United Kingdom.

Malcolm Irving (M)

Randall Centre for Cell and Molecular Biophysics and British Heart Foundation Centre of Research Excellence, King's College London, London SE1 1UL, United Kingdom.

Kenneth S Campbell (KS)

Department of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky 40536-0298.

Yin-Biao Sun (YB)

Randall Centre for Cell and Molecular Biophysics and British Heart Foundation Centre of Research Excellence, King's College London, London SE1 1UL, United Kingdom.

Thomas Kampourakis (T)

Randall Centre for Cell and Molecular Biophysics and British Heart Foundation Centre of Research Excellence, King's College London, London SE1 1UL, United Kingdom thomas.kampourakis@kcl.ac.uk.

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