Risk factors and spatial relative risk assessment for influenza A virus in poultry and swine in backyard production systems of central Chile.


Journal

Veterinary medicine and science
ISSN: 2053-1095
Titre abrégé: Vet Med Sci
Pays: England
ID NLM: 101678837

Informations de publication

Date de publication:
08 2020
Historique:
received: 02 07 2019
revised: 24 10 2019
accepted: 06 02 2020
pubmed: 23 2 2020
medline: 16 3 2021
entrez: 23 2 2020
Statut: ppublish

Résumé

Backyard production systems (BPS) are a common form of poultry and swine production worldwide. The limited implementation of biosecurity standards in these operations makes BPS a potential source for the emergence of pathogens that have an impact on both animal and public health. Information regarding circulation of influenza A virus (IAV) in poultry and swine raised in BPS is scarce; particularly in South American countries. The objective of this study was to estimate prevalence and seroprevalence of IAV in BPS in central Chile, identify subtype diversity, evaluate risk factors and spatial relative risk for IAV. Samples were collected from 329 BPS from central Chile. Seroprevalence at BPS level was 34.7% (95% CI: 23.1%-46.2%), 19.7% (95% CI: 9.9%-30.6%) and 11.7% (95% CI: 7.2%-16.4%), whereas prevalence at BPS level was 4.2% (95% CI: 0.0%-8.8%), 8.2% (95% CI: 0.8%-14.0%) and 9.2% (95% CI: 4.8%-13.1%), for the Metropolitan, Valparaiso and LGB O'Higgins regions, respectively. Spatial analysis revealed that central-western area of Metropolitan region and the southern province of Valparaiso region could be considered as high-risk areas for IAV (spatial relative risk = 2.2, p < .05). Logistic regression models identified the practice of breeding both poultry and pigs at the BPS as a risk factor (95% CI 1.06-3.75). From 75 IAV ELISA-positive sera, 20 chicken sera had haemagglutination inhibition titres ranging from 20 to 160, and of these, 11 had microneutralization titres ranging from 40 to 960 for one or more IAV subtypes. Identified subtypes were H1, H3, H4, H9, H10 and H12. Results from this study highlight the need for further IAV surveillance programmes in BPS in Chile. Early detection of IAV strains circulating in backyard animals, especially in regions with large human populations, could have an enormous impact on animal and public health.

Identifiants

pubmed: 32086880
doi: 10.1002/vms3.254
pmc: PMC7397882
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

518-526

Subventions

Organisme : NIAID NIH HHS
ID : HHSN272201400006C
Pays : United States
Organisme : National Institute of Allergy and Infectious Diseases
ID : HHSN272201400006
Pays : International

Informations de copyright

© 2020 The Authors. Veterinary Medicine and Science Published by John Wiley & Sons Ltd.

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Auteurs

Nicolas Bravo-Vasquez (N)

Department of Infectious Diseases, Saint Jude Children's Research Hospital, Memphis, TN, USA.

Cecilia Baumberger (C)

Department of Preventive Veterinary Medicine, University of Chile, Santiago de Chile, Chile.

Pedro Jimenez-Bluhm (P)

Department of Preventive Veterinary Medicine, University of Chile, Santiago de Chile, Chile.

Francisca Di Pillo (F)

Núcleo de Investigaciones Aplicadas en Ciencias Veterinarias y Agronómicas, Universidad de Las Americas, Santiago, Chile.

Andres Lazo (A)

Department of Preventive Veterinary Medicine, University of Chile, Santiago de Chile, Chile.

Juan Sanhueza (J)

Department of Veterinary Population Medicine, University of Minnesota Twin Cities, St Paul, MN, USA.

Stacey Schultz-Cherry (S)

Department of Infectious Diseases, Saint Jude Children's Research Hospital, Memphis, TN, USA.

Christopher Hamilton-West (C)

Department of Preventive Veterinary Medicine, University of Chile, Santiago de Chile, Chile.

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Classifications MeSH