Visual memory in offspring of parents with mental illness.

Child psychiatry Cognition Offspring of affected parents Severe mental illness Youth at-risk

Journal

Psychiatry research
ISSN: 1872-7123
Titre abrégé: Psychiatry Res
Pays: Ireland
ID NLM: 7911385

Informations de publication

Date de publication:
31 Jan 2020
Historique:
received: 08 09 2019
revised: 21 01 2020
accepted: 25 01 2020
pubmed: 23 2 2020
medline: 23 2 2020
entrez: 23 2 2020
Statut: aheadofprint

Résumé

Severe mental illness (SMI) refers to impairing and frequently chronic disorders that are difficult to treat. Lower cognitive performance early in life may be a manifestation of risk for SMI. Visual memory has been highlighted as a potential cognitive predictor of future risk of developing bipolar disorder and schizophrenia. We examined visual memory in 214 participants (mean age = 12.62, SD = 4.49) using the Rey Complex Figure Test (RCFT). Our sample included 37 offspring with no parental history of mental illness, 103 offspring with parental history of non-severe mental illness (NSMI), and 74 offspring with parental history of SMI. We tested the effects of family history of mental illness on visual memory using mixed-effects linear regression. After accounting for age, sex, and family clustering, we found that as severity of parental mental illness increases, offspring visual memory performance decreases significantly (b = -3.58, 95% CI -6.79 to -0.37, p = 0.029). We found that severity of parental mental illness predicts visual memory ability. This finding may help identify youth most at risk of developing mental illness and thus inform future interventions.

Identifiants

pubmed: 32087447
pii: S0165-1781(19)31789-5
doi: 10.1016/j.psychres.2020.112813
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

112813

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration Competing of Interest None.

Auteurs

Emily Howes Vallis (E)

Dalhousie University, Department of Psychiatry, Halifax, NS, Canada; Nova Scotia Health Authority, Halifax, NS, Canada.

Lynn E MacKenzie (LE)

Nova Scotia Health Authority, Halifax, NS, Canada; Dalhousie University, Department of Psychology and Neuroscience, Halifax, NS, Canada.

Sheri Rempel (S)

Nova Scotia Health Authority, Halifax, NS, Canada.

Meg Stephens (M)

Nova Scotia Health Authority, Halifax, NS, Canada.

Cynthia Howard (C)

Nova Scotia Health Authority, Halifax, NS, Canada.

Vladislav Drobinin (V)

Nova Scotia Health Authority, Halifax, NS, Canada; IWK Health Centre, Halifax, NS, Canada.

Lukas Propper (L)

Dalhousie University, Department of Psychiatry, Halifax, NS, Canada; Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

Antonina Omisade (A)

Nova Scotia Health Authority, Halifax, NS, Canada; Dalhousie University, Department of Psychology and Neuroscience, Halifax, NS, Canada.

Barbara Pavlova (B)

Dalhousie University, Department of Psychiatry, Halifax, NS, Canada; Nova Scotia Health Authority, Halifax, NS, Canada.

Rudolf Uher (R)

Dalhousie University, Department of Psychiatry, Halifax, NS, Canada; Nova Scotia Health Authority, Halifax, NS, Canada; Dalhousie University, Department of Psychology and Neuroscience, Halifax, NS, Canada; Dalhousie University, Department of Medical Neuroscience, Halifax, NS, Canada; IWK Health Centre, Halifax, NS, Canada; Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK. Electronic address: uher@dal.ca.

Classifications MeSH