Ovariectomy-induced depressive-like behavior and brain glucose metabolism changes in female rats are not affected by chronic mild stress.

Animals Behavior, Animal / physiology Brain / metabolism Depression / etiology Disease Models, Animal Female Ovariectomy Rats Rats, Wistar Stress, Psychological / complications
Brain metabolism Chronic mild stress Depression Estrogen depletion Positron emission tomography

Journal

Psychoneuroendocrinology
ISSN: 1873-3360
Titre abrégé: Psychoneuroendocrinology
Pays: England
ID NLM: 7612148

Informations de publication

Date de publication:
05 2020
Historique:
received: 20 05 2019
revised: 23 09 2019
accepted: 29 01 2020
pubmed: 24 2 2020
medline: 20 4 2021
entrez: 24 2 2020
Statut: ppublish

Résumé

The increased incidence of depression in women going through peri-menopause suggests that fluctuations in estrogen levels may increase the risk of developing depression. Nonetheless, this psychiatric disorder is likely to be multifactorial and consequently an additional trigger may be needed to induce depression in this population. Stress could be such a trigger. We therefore investigated the effect of ovarian estrogen depletion and chronic mild stress (CMS) on depressive-like behavior and brain metabolism in female rats. Approximately 2 and 9 weeks after estrogen depletion by ovariectomy, behavioral changes were assessed in the open-field test and the forced swim test, and brain metabolism was measured with [

Identifiants

DOI: 10.1016/j.psyneuen.2020.104610 PMID: 32088632
pubmed: 32088632
pii: S0306-4530(20)30029-9
doi: 10.1016/j.psyneuen.2020.104610
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

104610

Informations de copyright

Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest None.

Auteurs

M A Khayum (MA)

Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands.

R Moraga-Amaro (R)

Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands; Research School of Behavioural and Cognitive Neurosciences (BCN), University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

B Buwalda (B)

Behavioral Physiology, University of Groningen, Nijenborgh 7, 9747 AG, Groningen, the Netherlands.

M Koole (M)

Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands.

J A den Boer (JA)

Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands; PRA-Health Sciences, Van Swietenlaan, 9728 NZ, Groningen, the Netherlands.

R A J O Dierckx (RAJO)

Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands.

J Doorduin (J)

Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands.

E F J de Vries (EFJ)

Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands. Electronic address: e.f.j.de.vries@umcg.nl.

Articles similaires

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Meal Timing and Anthropometric and Metabolic Outcomes: A Systematic Review and Meta-Analysis.

Hiu Yee Liu, Ashley A Eso, Nathan Cook et al.
1.00
Humans Meals Time Factors Female Adult

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Ovariectomy-induced depressive-like behavior...
questionsmedicales.fr › Comportement et mécanismes comportementaux › Comportement › Comportement animal › Ovariectomy-induced depressive-like behavior...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Ovariectomy-induced depressive-like behavior...
questionsmedicales.fr › Comportement et mécanismes comportementaux › Émotions › Dépression › Ovariectomy-induced depressive-like behavior...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Ovariectomy-induced depressive-like behavior...
questionsmedicales.fr › Procédures de chirurgie opératoire › Procédures de chirurgie urogénitale › Procédures de chirurgie gynécologique › Ovariectomie › Ovariectomy-induced depressive-like behavior...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Ovariectomy-induced depressive-like behavior...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Wistar › Ovariectomy-induced depressive-like behavior...
questionsmedicales.fr › Phénomènes psychologiques › Stress psychologique › Ovariectomy-induced depressive-like behavior...