Spanish allele and haplotype database for 32 X-chromosome Insertion-Deletion polymorphisms.
Allele frequencies
Haplotype frequencies
Spanish population
X-InDels
Journal
Forensic science international. Genetics
ISSN: 1878-0326
Titre abrégé: Forensic Sci Int Genet
Pays: Netherlands
ID NLM: 101317016
Informations de publication
Date de publication:
05 2020
05 2020
Historique:
received:
18
06
2019
revised:
27
01
2020
accepted:
08
02
2020
pubmed:
24
2
2020
medline:
23
3
2021
entrez:
24
2
2020
Statut:
ppublish
Résumé
X-chromosome markers have been proved to be decisive both complementing and solving kinship analysis, particularly when autosomal markers are not able to produce adequate likelihood ratios between different hypothesis. On the other hand, Pereira et al., (2012) have demonstrated that 32 Insertion/Deletion (InDel) markers located on the X-Chromosome have a very important power of discrimination in human populations, being a novel tool in the forensic and population fields. So, the aim of the present work was testing the forensic and population genetic efficiency of the 32 X-InDel polymorphisms in the Spanish population, and subsequently build an allele/haplotype frequencies database. To accomplish this objective, a total of 555 samples comprising male individuals from 13 Spanish regions were analysed for the above mentioned 32 X-InDels in two independent laboratories. A pairwise F
Identifiants
pubmed: 32088644
pii: S1872-4973(20)30033-8
doi: 10.1016/j.fsigen.2020.102262
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
102262Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors have declared no conflict of interest.