Risk Factors for Complicated Lymphadenitis Caused by Nontuberculous Mycobacteria in Children.
Adolescent
Age Factors
Austria
/ epidemiology
Child
Child, Preschool
Female
Germany
/ epidemiology
Humans
Infant
Infant, Newborn
Lymphadenitis
/ epidemiology
Male
Mycobacterium Infections, Nontuberculous
/ epidemiology
Nontuberculous Mycobacteria
/ isolation & purification
Registries
Retrospective Studies
Risk Factors
Seasons
Sex Factors
Austria
Germany
Nontuberculous mycobacteria
bacteria
children
epidemiology
lymphadenitis
risk factors
tuberculosis and other mycobacteria
Journal
Emerging infectious diseases
ISSN: 1080-6059
Titre abrégé: Emerg Infect Dis
Pays: United States
ID NLM: 9508155
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
entrez:
25
2
2020
pubmed:
25
2
2020
medline:
16
3
2021
Statut:
ppublish
Résumé
Nontuberculous mycobacteria (NTM) are an emerging cause of infections, including chronic lymphadenitis in children. To identify risk factors for NTM lymphadenitis, particularly complicated disease, we collected epidemiologic, clinical, and microbiological data on 138 cases of NTM lymphadenitis in children across 13 centers in Germany and Austria. We assessed lifestyle factors but did not identify specific risk behaviors. We noted that more cases of NTM lymphadenitis occurred during cold months than during warm months. Moreover, we noted female sex and age <5.5 years as potential risk factors. Complete extirpation of the affected lymph node appeared to be the best therapeutic measure. We integrated the study data to develop a simple risk score to predict unfavorable clinical outcomes for NTM lymphadenitis.
Identifiants
pubmed: 32091372
doi: 10.3201/eid2603.191388
pmc: PMC7045849
doi:
Types de publication
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
579-586Références
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2007 May-Jun;50(5-6):533-46
pubmed: 17514437
Tuber Lung Dis. 1995 Aug;76(4):300-10
pubmed: 7579311
Am J Respir Crit Care Med. 2007 Feb 15;175(4):367-416
pubmed: 17277290
Swiss Med Wkly. 2001 Aug 11;131(31-32):445-54
pubmed: 11641967
Pediatr Infect Dis J. 2009 Jul;28(7):642-4
pubmed: 19561429
Antonie Van Leeuwenhoek. 2018 Jan;111(1):73-87
pubmed: 28836034
Clin Infect Dis. 1995 Apr;20(4):954-63
pubmed: 7795100
Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16393-9
pubmed: 19805310
J Clin Microbiol. 2013 Sep;51(9):3006-11
pubmed: 23843489
PLoS One. 2015 Jun 08;10(6):e0129073
pubmed: 26052701
Clin Infect Dis. 2007 Apr 15;44(8):1057-64
pubmed: 17366449
Clin Infect Dis. 2011 Jan 15;52(2):180-4
pubmed: 21288841
PLoS One. 2016 Jan 26;11(1):e0147513
pubmed: 26812154
J Pediatr. 1979 Sep;95(3):356-60
pubmed: 469659
J Water Health. 2015 Jun;13(2):553-61
pubmed: 26042986
Clin Infect Dis. 2004 Aug 15;39(4):450-6
pubmed: 15356803
Eur Respir J. 2013 Dec;42(6):1604-13
pubmed: 23598956
Emerg Infect Dis. 2008 Apr;14(4):661-3
pubmed: 18394289
Lancet Infect Dis. 2015 Aug;15(8):968-80
pubmed: 26049967
Curr Opin Pulm Med. 2009 May;15(3):201-8
pubmed: 19305349
Respirology. 2013 Aug;18(6):983-8
pubmed: 23627546
J Infect. 2014 Jan;68 Suppl 1:S134-50
pubmed: 24119826
J Infect Dis. 2000 Jun;181(6):2099-102
pubmed: 10837203