Human radical scavenger α

Alpha-Globulins Anemia, Macrocytic Animals Cell Death Erythrocytes Hemolysis Humans Mice Mice, Knockout Phenotype
Antioxidant defense Hemolysis Knock-out mouse Oxidative stress Red blood cells α(1)-microglobulin

Journal

Free radical biology & medicine
ISSN: 1873-4596
Titre abrégé: Free Radic Biol Med
Pays: United States
ID NLM: 8709159

Informations de publication

Date de publication:
01 2021
Historique:
received: 19 11 2019
revised: 14 02 2020
accepted: 19 02 2020
pubmed: 25 2 2020
medline: 22 6 2021
entrez: 25 2 2020
Statut: ppublish

Résumé

During red blood cell (RBC) lysis hemoglobin and heme leak out of the cells and cause damage to the endothelium and nearby tissue. Protective mechanisms exist; however, these systems are not sufficient in diseases with increased extravascular hemolysis e.g. hemolytic anemia. α

Identifiants

DOI: 10.1016/j.freeradbiomed.2020.02.018 PMID: 32092412
pubmed: 32092412
pii: S0891-5849(19)32350-0
doi: 10.1016/j.freeradbiomed.2020.02.018
pii:
doi:

Substances chimiques

Alpha-Globulins 0
alpha-1-microglobulin 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

149-159

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Amanda Kristiansson (A)

Section for Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden. Electronic address: amanda.kristiansson@med.lu.se.

Jesper Bergwik (J)

Section for Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden.

Abdul Ghani Alattar (AG)

Division of Molecular Medicine and Gene Therapy, Lund Stem Cell Centre, Department of Laboratory Medicine, Lund University, Lund, Sweden; Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden.

Johan Flygare (J)

Division of Molecular Medicine and Gene Therapy, Lund Stem Cell Centre, Department of Laboratory Medicine, Lund University, Lund, Sweden.

Magnus Gram (M)

Section for Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden.

Stefan R Hansson (SR)

Department of Obstetrics and Gynecology, Department of Clinical Sciences, Lund University, Lund, Sweden.

Martin L Olsson (ML)

Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden; Department of Clinical Immunology and Transfusion Medicine, Office of Medical Services, Lund, Sweden.

Jill R Storry (JR)

Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden; Department of Clinical Immunology and Transfusion Medicine, Office of Medical Services, Lund, Sweden.

Maria Allhorn (M)

Section for Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden.

Bo Åkerström (B)

Section for Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › alpha-Globulines › Human radical scavenger α
questionsmedicales.fr › Hémopathies et maladies lymphatiques › Hémopathies › Anémie › Anémie macrocytaire › Human radical scavenger α
questionsmedicales.fr › Eucaryotes › Animaux › Human radical scavenger α
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Mort cellulaire › Human radical scavenger α
questionsmedicales.fr › Systèmes sanguin et immunitaire › Sang › Cellules sanguines › Érythrocytes › Human radical scavenger α
questionsmedicales.fr › Phénomènes du système immunitaire › Réaction antigène-anticorps › Hémolyse › Human radical scavenger α
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Human radical scavenger α
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Human radical scavenger α
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › Human radical scavenger α
questionsmedicales.fr › Phénomènes génétiques › Phénotype › Human radical scavenger α