New Drugs for Human African Trypanosomiasis: A Twenty First Century Success Story.
acoziborole
chemotherapy
elimination
fexinidazole
human African trypanosomiasis
pafuramidine
sleeping sickness
Journal
Tropical medicine and infectious disease
ISSN: 2414-6366
Titre abrégé: Trop Med Infect Dis
Pays: Switzerland
ID NLM: 101709042
Informations de publication
Date de publication:
19 Feb 2020
19 Feb 2020
Historique:
received:
16
01
2020
revised:
12
02
2020
accepted:
14
02
2020
entrez:
26
2
2020
pubmed:
26
2
2020
medline:
26
2
2020
Statut:
epublish
Résumé
The twentieth century ended with human African trypanosomiasis (HAT) epidemics raging across many parts of Africa. Resistance to existing drugs was emerging, and many programs aiming to contain the disease had ground to a halt, given previous success against HAT and the competing priorities associated with other medical crises ravaging the continent. A series of dedicated interventions and the introduction of innovative routes to develop drugs, involving Product Development Partnerships, has led to a dramatic turnaround in the fight against HAT caused by
Identifiants
pubmed: 32092897
pii: tropicalmed5010029
doi: 10.3390/tropicalmed5010029
pmc: PMC7157223
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Medical Research Council
ID : MR/L018853/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S019650/1
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 104111/Z/14/Z
Pays : United Kingdom
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