Elevated incidence of alveolar echinococcosis in immunocompromised patients.
Alveolar echinococcosis, (AE)
Benzimidazole
Echinoccocosis
Echinococcus multilocularis
Echinococcus multilocularis, (E. multilocularis)
Immunosuppression
alveolar_echinococcosis
benzimidazole, (BZM)
immunocompetent, (ICT)
immunocompromised, (ICR)
Journal
Food and waterborne parasitology
ISSN: 2405-6766
Titre abrégé: Food Waterborne Parasitol
Pays: Netherlands
ID NLM: 101762332
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
11
02
2019
revised:
21
05
2019
accepted:
21
05
2019
entrez:
26
2
2020
pubmed:
26
2
2020
medline:
26
2
2020
Statut:
epublish
Résumé
Recent experimental data has revealed that the course of alveolar echinococcosis (AE) depends on adaptive immunity. For this study, we aimed to analyze the incidence and outcome of AE in immunocompromised humans. Retrospective analysis of 131 patients with a median age of 54 years treated for AE between 1971 and 2017 at a Swiss tertiary referral Centre. Fifty-two percent were females and 65 patients (50%) were diagnosed incidentally. Fourteen patients (16%) were operated on laparoscopically. Overall, median follow-up was 48 months. New diagnoses have increased fourfold in immunocompetent and tenfold in immunocompromised patients in the past decade ( The incidence of human AE has increased over the last 2 decades with surgical interventions resulting in excellent outcomes. We have observed an association of immunosuppressive conditions with both incidence and survival of AE eventually justifying the implementation of a screening program for patients at risk in endemic regions.
Identifiants
pubmed: 32095630
doi: 10.1016/j.fawpar.2019.e00060
pii: S2405-6766(19)30012-5
pii: e00060
pmc: PMC7034048
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e00060Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2019 Published by Elsevier Inc. on behalf of International Association of Food and Waterborne Parasitology.
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