New Strategies to Enhance Myocardial Regeneration: Expectations and Challenges from Preclinical Evidence.
Myocardial infarction
cardiac regeneration
cell therapy
clinical translation
preclinical model
stem cells
Journal
Current stem cell research & therapy
ISSN: 2212-3946
Titre abrégé: Curr Stem Cell Res Ther
Pays: United Arab Emirates
ID NLM: 101272517
Informations de publication
Date de publication:
2020
2020
Historique:
received:
20
09
2019
revised:
12
12
2019
accepted:
03
01
2020
pubmed:
26
2
2020
medline:
30
10
2021
entrez:
26
2
2020
Statut:
ppublish
Résumé
Nowadays, cardiac regeneration is an emerging topic in the cardiovascular field because of the compelling need for effective therapies for repairing or replacing cardiac tissue damaged by pathological or physiological conditions. Indeed, irreversible myocardial remodeling which follows acute myocardial infarction represents a serious burden of this century. In this context, a great improvement in pharmacological and interventional techniques is accompanied by a big challenge of cardiac regenerative medicine. In the last 20 years, several clinical trials tried to investigate the role of different types of stem cells in promoting cardiac repair. However, the promising results obtained in the preclinical trials have not yet been reproduced in patients. Thus, the development of novel strategies to improve stem cell efficiency became imperative. Here, an overview of the more recent cell types proposed for cardiac regeneration is presented, together with the most interesting approaches to enhance cell regenerative potential as well as cell-free approaches.
Identifiants
pubmed: 32096748
pii: CSCR-EPUB-104823
doi: 10.2174/1574888X15666200225124451
pmc: PMC8493790
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
696-710Informations de copyright
Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
Références
Stem Cells Dev. 2012 Apr 10;21(6):977-86
pubmed: 22182484
ACS Chem Biol. 2014 Jan 17;9(1):57-71
pubmed: 24372447
Circulation. 2013 Sep 10;128(11 Suppl 1):S87-94
pubmed: 24030425
Cell Biol Int. 2015 Nov;39(11):1251-63
pubmed: 26032287
Stem Cells Transl Med. 2014 Jul;3(7):821-35
pubmed: 24833591
Exp Cell Res. 2016 May 15;344(1):30-39
pubmed: 27025401
Nature. 2015 Sep 24;525(7570):479-85
pubmed: 26375005
PLoS One. 2011;6(7):e22158
pubmed: 21789227
Nat Commun. 2017 Jan 03;8:13724
pubmed: 28045024
Circulation. 2018 Apr 17;137(16):1712-1730
pubmed: 29233823
Circulation. 2010 Apr 20;121(15):1735-45
pubmed: 20368523
Stem Cell Res Ther. 2015 Aug 22;6:147
pubmed: 26296645
Circulation. 2009 Sep 8;120(10):876-87
pubmed: 19704095
Physiol Rev. 2016 Jul;96(3):1127-68
pubmed: 27335447
Adv Healthc Mater. 2019 Jan;8(2):e1801011
pubmed: 30548836
Cytotherapy. 2015 Sep;17(9):1302-13
pubmed: 26038175
Int J Mol Sci. 2019 Mar 21;20(6):
pubmed: 30901815
Front Biosci (Landmark Ed). 2016 Jun 01;21:1126-50
pubmed: 27100496
Transplantation. 2005 Dec 15;80(11):1586-95
pubmed: 16371930
Sci Rep. 2017 Apr 03;7:45641
pubmed: 28368043
Basic Res Cardiol. 2013 Mar;108(2):333
pubmed: 23386286
Circ Res. 2017 Feb 17;120(4):701-712
pubmed: 27872050
Stem Cells. 2008 Jul;26(7):1695-704
pubmed: 18420831
Front Pharmacol. 2017 Mar 17;8:135
pubmed: 28367125
Eur J Heart Fail. 2016 Feb;18(2):133-41
pubmed: 26470631
Nat Chem Biol. 2014 Jul;10(7):558-66
pubmed: 24845231
J Mol Cell Cardiol. 1992 Aug;24(8):895-907
pubmed: 1433316
Mol Cell Biochem. 2014 Dec;397(1-2):203-14
pubmed: 25134935
J Am Coll Cardiol. 2017 Aug 8;70(6):766-775
pubmed: 28774384
Biomaterials. 2014 Oct;35(30):8528-39
pubmed: 25043570
Circ Res. 2017 Jan 20;120(2):332-340
pubmed: 27856497
Am J Transl Res. 2015 Dec 15;7(12):2738-51
pubmed: 26885271
Curr Stem Cell Res Ther. 2016;11(4):352-69
pubmed: 26996232
J Cell Mol Med. 2017 Sep;21(9):1751-1766
pubmed: 28244640
Cell. 2006 Aug 25;126(4):663-76
pubmed: 16904174
Obesity (Silver Spring). 2010 Aug;18(8):1516-23
pubmed: 20075852
Shock. 2010 Jan;33(1):24-30
pubmed: 19996917
Angew Chem Int Ed Engl. 2011 Jan 3;50(1):200-42
pubmed: 21184400
Tissue Eng Part A. 2011 May;17(9-10):1219-28
pubmed: 21187004
Cardiovasc Ther. 2017 Apr;35(2):
pubmed: 28039940
Front Physiol. 2018 Nov 19;9:1159
pubmed: 30524292
Biol Chem. 2016 Dec 1;397(12):1355-1364
pubmed: 27420897
Mol Med Rep. 2015 Feb;11(2):815-20
pubmed: 25351395
Biologicals. 2018 May;53:10-18
pubmed: 29625872
Nat Biomed Eng. 2018;2:17-26
pubmed: 29862136
Stem Cell Res. 2010 May;4(3):214-22
pubmed: 20138817
Stem Cells. 2016 Jul;34(7):1826-35
pubmed: 27059540
Stem Cell Res Ther. 2017 Sep 29;8(1):202
pubmed: 28962583
Leuk Res. 2015 Jul;39(7):779-85
pubmed: 25982178
Front Immunol. 2017 Jun 02;8:645
pubmed: 28626459
J Cardiovasc Pharmacol. 2015 Mar;65(3):241-51
pubmed: 25658461
ACS Nano. 2018 Aug 28;12(8):7826-7837
pubmed: 30016078
Cell Stem Cell. 2014 Dec 4;15(6):750-61
pubmed: 25479750
J Tissue Eng Regen Med. 2018 Feb;12(2):546-556
pubmed: 28875579
Stem Cells. 2014 Feb;32(2):462-72
pubmed: 24123326
Circulation. 2006 Dec 19;114(25):2823-30
pubmed: 17145991
Pathophysiology. 2016 Jun;23(2):95-104
pubmed: 27102896
Cell Stress Chaperones. 2016 Nov;21(6):1089-1099
pubmed: 27565660
Cardiovasc Res. 2008 Jan;77(1):134-42
pubmed: 18006467
Nat Med. 2008 Feb;14(2):213-21
pubmed: 18193059
Circ Res. 2011 Sep 16;109(7):724-8
pubmed: 21835908
Stem Cell Res Ther. 2013;4(6):149
pubmed: 24330751
Nature. 2017 Jul 13;547(7662):179-184
pubmed: 28581497
Cell Physiol Biochem. 2018;48(6):2607-2655
pubmed: 30121644
Basic Res Cardiol. 2011 Nov;106(6):1283-97
pubmed: 21952733
Stem Cells. 2007 Mar;25(3):712-7
pubmed: 17138964
Nature. 2018 May;557(7707):619-620
pubmed: 29844563
Nature. 2016 Oct 20;538(7625):388-391
pubmed: 27723741
Int J Clin Exp Pathol. 2015 Mar 01;8(3):2505-14
pubmed: 26045756
ACS Appl Mater Interfaces. 2018 Oct 3;10(39):33088-33096
pubmed: 30188113
Circ J. 2011;75(4):852-60
pubmed: 21301134
Stem Cells. 2012 Feb;30(2):326-35
pubmed: 22102597
Acta Biomater. 2018 Oct 15;80:154-168
pubmed: 30218777
NPJ Regen Med. 2017 Mar 3;2:4
pubmed: 29302341
Stem Cells Int. 2015;2015:761643
pubmed: 26106430
Stem Cells Transl Med. 2016 Jun;5(6):793-803
pubmed: 27112177
Int J Cardiol. 2019 Jul 15;287:87-95
pubmed: 30987834
Mol Ther. 2006 Dec;14(6):840-50
pubmed: 16965940
Blood. 2003 Oct 15;102(8):2728-30
pubmed: 12855591
J Am Coll Cardiol. 2018 Jan 30;71(4):429-438
pubmed: 29389360
PLoS One. 2013 Nov 14;8(11):e80186
pubmed: 24244646
Stem Cell Rev Rep. 2019 Oct;15(5):637-651
pubmed: 31254166
Nat Med. 2006 Apr;12(4):459-65
pubmed: 16582917
Biomed Res Int. 2014;2014:872984
pubmed: 24900995
J Vasc Res. 2017;54(2):100-108
pubmed: 28407626
Circ Res. 2015 May 8;116(10):e81-94
pubmed: 25801898
PLoS One. 2013 Sep 12;8(9):e75010
pubmed: 24069374
Mech Ageing Dev. 2016 Oct;159:4-13
pubmed: 27045606
Science. 1998 Jul 10;281(5374):257-9
pubmed: 9657720
Basic Res Cardiol. 2011 Jun;106(4):645-55
pubmed: 21416207
Oncotarget. 2017 May 4;8(39):64853-64866
pubmed: 29029396
Sci Rep. 2016 Oct 21;6:35489
pubmed: 27765951
Circulation. 2019 Mar 5;139(10):e56-e528
pubmed: 30700139
Circ Res. 2016 Jan 8;118(1):95-107
pubmed: 26837742
Circulation. 2017 Jul 11;136(2):200-214
pubmed: 28411247
Circ Res. 2011 Aug 5;109(4):360-4
pubmed: 21737789
Apoptosis. 2016 Dec;21(12):1336-1353
pubmed: 27696124
Circ Res. 2017 May 26;120(11):1768-1775
pubmed: 28298296
Biomaterials. 2015 Aug;61:339-48
pubmed: 26043062
PLoS One. 2014 Feb 18;9(2):e88685
pubmed: 24558412
Circ Res. 2016 Oct 14;119(9):988-991
pubmed: 27737943
Eur J Heart Fail. 2017 Jan;19(1):148-157
pubmed: 28052545
ChemMedChem. 2012 Feb 6;7(2):209-12
pubmed: 22190478
Biomaterials. 2012 Jun;33(19):4792-800
pubmed: 22483246
Circ Res. 2015 Jun 19;117(1):52-64
pubmed: 25904597
J Am Heart Assoc. 2015 Sep 11;4(9):e002104
pubmed: 26363004
Acta Pharmacol Sin. 2018 Apr;39(4):579-586
pubmed: 29542684
Int J Clin Exp Pathol. 2015 Feb 01;8(2):2221-34
pubmed: 25973133
Macromol Biosci. 2013 Aug;13(8):984-1019
pubmed: 23836778
Acta Biomater. 2018 Mar 1;68:1-14
pubmed: 29274480
Chem Biol. 2011 Dec 23;18(12):1658-68
pubmed: 22195568
Semin Cell Dev Biol. 2012 Dec;23(9):963-70
pubmed: 23059791
J Am Coll Cardiol. 2005 Nov 15;46(10):1799-802
pubmed: 16286162
J Biomed Mater Res A. 2014 Sep;102(9):3263-72
pubmed: 24142588
Mol Pharm. 2011 Oct 3;8(5):1446-57
pubmed: 21591779
Theranostics. 2018 Feb 14;8(7):1869-1878
pubmed: 29556361
Circ Res. 2008 Nov 21;103(11):1204-19
pubmed: 19028920
J Med Chem. 2012 Jan 26;55(2):697-708
pubmed: 22191557
Theranostics. 2013;3(1):47-75
pubmed: 23382786
Circulation. 2013 Feb 12;127(6):749-56
pubmed: 23401116
Semin Cell Dev Biol. 2015 Jan;37:58-65
pubmed: 25263014
Crit Rev Biochem Mol Biol. 2013 Sep-Oct;48(5):430-45
pubmed: 23879520
Stem Cell Res. 2007 Nov;1(2):129-37
pubmed: 19383393
Int J Mol Sci. 2016 Oct 20;17(10):
pubmed: 27775615
Stem Cell Res. 2013 May;10(3):301-12
pubmed: 23399448
J Pharmacol Exp Ther. 2009 May;329(2):543-50
pubmed: 19218529
Sci Rep. 2015 Nov 16;5:16662
pubmed: 26567861
Biochem Biophys Res Commun. 2009 Sep 18;387(2):353-9
pubmed: 19595673
Stem Cells. 2007 Aug;25(8):2118-27
pubmed: 17478584
Eur J Cardiothorac Surg. 2013 May;43(5):1050-7
pubmed: 23100292
Cell Physiol Biochem. 2015;37(6):2415-24
pubmed: 26646808
Nat Biomed Eng. 2017;1:983-992
pubmed: 29354322
Hum Reprod Update. 2016 Mar-Apr;22(2):137-63
pubmed: 26552890
Cell Mol Life Sci. 2019 May;76(9):1681-1695
pubmed: 30721319
Circulation. 2006 Jul 4;114(1 Suppl):I167-73
pubmed: 16820568
Cardiovasc Res. 2014 Sep 1;103(4):530-41
pubmed: 25016614
Stem Cell Rev Rep. 2017 Feb;13(1):7-16
pubmed: 27592701
Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H590-5
pubmed: 18156196
Circulation. 2008 Mar 18;117(11):1388-96
pubmed: 18316487
Stem Cells. 2018 Sep;36(9):1295-1310
pubmed: 29732653
Science. 2004 Aug 13;305(5686):1000-3
pubmed: 15310902
Blood Cells Mol Dis. 2004 Jan-Feb;32(1):82-7
pubmed: 14757418
Int J Cardiol. 2015 Mar 1;182:349-60
pubmed: 25590961
Stem Cells. 2017 Feb;35(2):337-350
pubmed: 27538588
Life Sci. 2016 May 15;153:124-31
pubmed: 27091653
J Nat Prod. 2000 May;63(5):631-5
pubmed: 10843574
Circ Res. 2011 Sep 30;109(8):894-906
pubmed: 21868695
Tissue Eng Part C Methods. 2017 Mar;23(3):146-155
pubmed: 28068869
Biochem Biophys Res Commun. 2008 Jul 11;371(4):752-5
pubmed: 18466761
Cardiovasc Res. 2015 Oct 1;108(1):39-49
pubmed: 26187727
Eur Heart J. 2017 Jan 14;38(3):201-211
pubmed: 28158410
Microcirculation. 2015 Nov;22(8):711-23
pubmed: 26243428
Stem Cells Int. 2018 Jan 16;2018:1909346
pubmed: 29535769
J Cell Physiol. 2019 Aug;234(10):16904-16912
pubmed: 30811054
Acta Biomater. 2016 Oct 15;44:209-20
pubmed: 27545814
Circ Heart Fail. 2015 Jan;8(1):156-66
pubmed: 25420485
PLoS One. 2016 Jan 13;11(1):e0146074
pubmed: 26760781
Eur Heart J. 2008 Jun;29(12):1578-90
pubmed: 18456710
Stem Cell Res. 2016 Jul;17(1):6-15
pubmed: 27186654
Adv Funct Mater. 2019 Jan 24;29(4):
pubmed: 32256277
PLoS One. 2010 Nov 29;5(11):e15521
pubmed: 21170416
Stem Cell Res Ther. 2016 Jul 16;7(1):94
pubmed: 27423905
PLoS One. 2008 Aug 06;3(8):e2904
pubmed: 18682835
Circulation. 2012 Sep 11;126(11 Suppl 1):S29-37
pubmed: 22965990
ACS Nano. 2017 Oct 24;11(10):9738-9749
pubmed: 28929735
Circ Res. 2006 Sep 29;99(7):776-84
pubmed: 16960098
Cardiovasc Res. 2015 Jul 15;107(2):277-86
pubmed: 26025956
Cell Transplant. 2016;25(9):1609-1622
pubmed: 26624235
Blood. 2005 Sep 1;106(5):1867-74
pubmed: 15890685
Cardiovasc Ther. 2015 Aug;33(4):184-92
pubmed: 25959676