Peripheral T cell expansion predicts tumour infiltration and clinical response.

Antibodies, Monoclonal, Humanized / therapeutic use Antineoplastic Agents / therapeutic use Clone Cells Humans Lymphocytes, Tumor-Infiltrating / cytology Neoplasms / drug therapy Pharmacogenomic Variants Receptors, Antigen, T-Cell / genetics T-Lymphocytes / cytology Transcriptome

Journal

Nature

ISSN: 1476-4687

Titre abrégé: Nature

Pays: England

ID NLM: 0410462

Informations de publication

Date de publication:
03 2020

Historique:

received: 27 09 2018

accepted: 08 01 2020

pubmed: 28 2 2020

medline: 21 3 2020

entrez: 28 2 2020

Statut: ppublish

Résumé

Despite the resounding clinical success in cancer treatment of antibodies that block the interaction of PD1 with its ligand PDL1

Identifiants

DOI: 10.1038/s41586-020-2056-8 PMID: 32103181

pubmed: 32103181

doi: 10.1038/s41586-020-2056-8

pii: 10.1038/s41586-020-2056-8

doi:

Substances chimiques

Antibodies, Monoclonal, Humanized 0

Antineoplastic Agents 0

Receptors, Antigen, T-Cell 0

atezolizumab 52CMI0WC3Y

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

274-278

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