Patient Health Questionnaire-9 scores do not accurately estimate depression prevalence: individual participant data meta-analysis.

Adolescent Adult Aged Databases, Factual Depression / epidemiology Diagnostic and Statistical Manual of Mental Disorders Female Humans Male Middle Aged Patient Health Questionnaire Prevalence Young Adult
Depression prevalence Individual participant data meta-analysis PHQ-9 SCID

Journal

Journal of clinical epidemiology
ISSN: 1878-5921
Titre abrégé: J Clin Epidemiol
Pays: United States
ID NLM: 8801383

Informations de publication

Date de publication:
06 2020
Historique:
received: 22 08 2019
revised: 08 02 2020
accepted: 18 02 2020
pubmed: 28 2 2020
medline: 28 1 2021
entrez: 28 2 2020
Statut: ppublish

Résumé

Depression symptom questionnaires are not for diagnostic classification. Patient Health Questionnaire-9 (PHQ-9) scores ≥10 are nonetheless often used to estimate depression prevalence. We compared PHQ-9 ≥10 prevalence to Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders (SCID) major depression prevalence and assessed whether an alternative PHQ-9 cutoff could more accurately estimate prevalence. Individual participant data meta-analysis of datasets comparing PHQ-9 scores to SCID major depression status. A total of 9,242 participants (1,389 SCID major depression cases) from 44 primary studies were included. Pooled PHQ-9 ≥10 prevalence was 24.6% (95% confidence interval [CI]: 20.8%, 28.9%); pooled SCID major depression prevalence was 12.1% (95% CI: 9.6%, 15.2%); and pooled difference was 11.9% (95% CI: 9.3%, 14.6%). The mean study-level PHQ-9 ≥10 to SCID-based prevalence ratio was 2.5 times. PHQ-9 ≥14 and the PHQ-9 diagnostic algorithm provided prevalence closest to SCID major depression prevalence, but study-level prevalence differed from SCID-based prevalence by an average absolute difference of 4.8% for PHQ-9 ≥14 (95% prediction interval: -13.6%, 14.5%) and 5.6% for the PHQ-9 diagnostic algorithm (95% prediction interval: -16.4%, 15.0%). PHQ-9 ≥10 substantially overestimates depression prevalence. There is too much heterogeneity to correct statistically in individual studies.

Identifiants

DOI: 10.1016/j.jclinepi.2020.02.002 PMID: 32105798
pubmed: 32105798
pii: S0895-4356(19)30735-8
doi: 10.1016/j.jclinepi.2020.02.002
pii:
doi:

Types de publication

Comparative Study Journal Article Meta-Analysis Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

115-128.e1

Subventions

Organisme : CIHR
ID : PJT-162206
Pays : Canada
Organisme : AHRQ HHS
ID : R36 HS018246
Pays : United States
Organisme : NIMH NIH HHS
ID : T32 MH014592
Pays : United States
Organisme : Medical Research Council
ID : MR/J000914/1
Pays : United Kingdom
Organisme : NCI NIH HHS
ID : K07 CA093512
Pays : United States
Organisme : NCI NIH HHS
ID : U10 CA021661
Pays : United States
Organisme : Department of Health
ID : RP-PG-0606-1142
Pays : United Kingdom
Organisme : NIGMS NIH HHS
ID : T32 GM007356
Pays : United States
Organisme : MRF
ID : MRF_C0396
Pays : United Kingdom
Organisme : NIMH NIH HHS
ID : R24 MH071604
Pays : United States
Organisme : NCI NIH HHS
ID : U10 CA180868
Pays : United States
Organisme : CIHR
ID : KRS-134297
Pays : Canada
Organisme : CIHR
ID : PCG-155468
Pays : Canada
Organisme : NIMH NIH HHS
ID : T32 MH103210
Pays : United States
Organisme : NCIPC CDC HHS
ID : R49 CE002093
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH069666
Pays : United States
Organisme : NCI NIH HHS
ID : U10 CA037422
Pays : United States
Organisme : CIHR
ID : THC-135234
Pays : Canada
Organisme : NCI NIH HHS
ID : U10 CA180822
Pays : United States
Organisme : NIMH NIH HHS
ID : R34 MH072925
Pays : United States
Organisme : NIMH NIH HHS
ID : K02 MH065919
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD039415
Pays : United States
Organisme : NCRR NIH HHS
ID : TL1 RR024135
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK050456
Pays : United States

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Brooke Levis (B)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada.

Andrea Benedetti (A)

Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada; Respiratory Epidemiology and Clinical Research Unit, McGill University Health Centre, Montréal, Québec, Canada; Department of Medicine, McGill University, Montréal, Québec, Canada.

John P A Ioannidis (JPA)

Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA, USA; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA; Department of Statistics, Stanford University School of Humanities and Sciences, Stanford, CA, USA.

Ying Sun (Y)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada.

Zelalem Negeri (Z)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada.

Chen He (C)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada.

Yin Wu (Y)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada; Department of Psychiatry, McGill University, Montréal, Québec, Canada.

Ankur Krishnan (A)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada.

Parash Mani Bhandari (PM)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada.

Dipika Neupane (D)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada.

Mahrukh Imran (M)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada.

Danielle B Rice (DB)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada; Department of Psychology, McGill University, Montréal, Québec, Canada.

Kira E Riehm (KE)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada; Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.

Nazanin Saadat (N)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada.

Marleine Azar (M)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada.

Jill Boruff (J)

Schulich Library of Physical Sciences, Life Sciences, and Engineering, McGill University, Montréal, Québec, Canada.

Pim Cuijpers (P)

Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

Simon Gilbody (S)

Hull York Medical School and the Department of Health Sciences, University of York, Heslington, NY, UK.

Lorie A Kloda (LA)

Library, Concordia University, Montréal, Québec, Canada.

Dean McMillan (D)

Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.

Scott B Patten (SB)

Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada; Hotchkiss Brain Institute and O'Brien Institute for Public Health, University of Calgary, Calgary, Alberta, Canada.

Ian Shrier (I)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada; Department of Family Medicine, McGill University, Montréal, Québec, Canada.

Roy C Ziegelstein (RC)

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Sultan H Alamri (SH)

Faculty of Medicine, King Abdulaziz University, Jeddah, Makkah, Saudi Arabia.

Dagmar Amtmann (D)

Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.

Liat Ayalon (L)

Louis and Gabi Weisfeld School of Social Work, Bar Ilan University, Ramat Gan, Israel.

Hamid R Baradaran (HR)

Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran; Ageing Clinical & Experimental Research Team, Institute of Applied Health Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, Scotland, UK.

Anna Beraldi (A)

Kbo-Lech-Mangfall-Klinik Garmisch-Partenkirchen, Klinik für Psychiatrie, Psychotherapie & Psychosomatik, Lehrkrankenhaus der Technischen Universität München, Munich, Germany.

Charles N Bernstein (CN)

University of Manitoba IBD Clinical and Research Centre, Winnipeg, Manitoba, Canada; Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Arvin Bhana (A)

Centre for Rural Health, School of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Durban, KwaZulu-Natal, South Africa; Health Systems Research Unit, South African Medical Research Council, Cape Town, South Africa.

Charles H Bombardier (CH)

Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.

Gregory Carter (G)

Centre for Brain and Mental Health Research, University of Newcastle, New South Wales, Australia.

Marcos H Chagas (MH)

Department of Neurosciences and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.

Dixon Chibanda (D)

Department of Community Medicine, University of Zimbabwe, Harare, Zimbabwe.

Kerrie Clover (K)

Centre for Brain and Mental Health Research, University of Newcastle, New South Wales, Australia.

Yeates Conwell (Y)

Department of Psychiatry, University of Rochester Medical Center, Rochester, NY, USA.

Crisanto Diez-Quevedo (C)

Servei de Psiquiatria, Hospital Germans Trias i Pujol, Badalona, Spain; Departament de Psiquiatria i Medicina Legal, Universitat Autònoma de Barcelona, Badalona, Spain.

Jesse R Fann (JR)

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.

Felix H Fischer (FH)

Department of Psychiatry, McGill University, Montréal, Québec, Canada; Department of Psychosomatic Medicine, Center for Internal Medicine and Dermatology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Leila Gholizadeh (L)

Faculty of Health, University of Technology Sydney, Sydney, Australia.

Lorna J Gibson (LJ)

Tropical Epidemiology Group, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

Eric P Green (EP)

Duke Global Health Institute, Duke University, Durham, NC, USA.

Catherine G Greeno (CG)

School of Social Work, University of Pittsburgh, Pittsburgh, PA, USA.

Brian J Hall (BJ)

Department of Psychology, Faculty of Social Sciences, Global and Community Mental Health Research Group, University of Macau, Macau Special Administrative Region, China; Department of Health, Behavior, and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Emily E Haroz (EE)

Center for American Indian Health, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Khalida Ismail (K)

Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neurosciences, King's College London Weston Education Centre, London, UK.

Nathalie Jetté (N)

Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada; Hotchkiss Brain Institute and O'Brien Institute for Public Health, University of Calgary, Calgary, Alberta, Canada; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Mohammad E Khamseh (ME)

Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran.

Yunxin Kwan (Y)

Department of Psychological Medicine, Tan Tock Seng Hospital, Singapore.

Maria Asunción Lara (MA)

Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz. San Lorenzo Huipulco, Tlalpan, México D. F. Mexico.

Shen-Ing Liu (SI)

Programme in Health Services & Systems Research, Duke-NUS Medical School, Singapore; Department of Psychiatry, Mackay Memorial Hospital, Taipei, Taiwan; Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan; Department of Medicine, Mackay Medical College, Taipei, Taiwan.

Sonia R Loureiro (SR)

Department of Neurosciences and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.

Bernd Löwe (B)

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Ruth Ann Marrie (RA)

Departments of Medicine and Community Health Sciences, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Laura Marsh (L)

Baylor College of Medicine, Houston and Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA.

Anthony McGuire (A)

Department of Nursing, St. Joseph's College, Standish, ME, USA.

Kumiko Muramatsu (K)

Department of Clinical Psychology, Graduate School of Niigata Seiryo University, Niigata, Japan.

Laura Navarrete (L)

Department of Epidemiology and Psychosocial Research, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, Mexico.

Flávia L Osório (FL)

Department of Neurosciences and Behavior, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil; National Institute of Science and Technology, Translational Medicine, Ribeirão Preto, Brazil.

Inge Petersen (I)

Centre for Rural Health, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.

Angelo Picardi (A)

Centre for Behavioural Sciences and Mental Health, Italian National Institute of Health, Rome, Italy.

Stephanie L Pugh (SL)

NRG Oncology Statistics and Data Management Center, Philadelphia, PA, USA; American College of Radiology, Philadelphia, PA, USA.

Terence J Quinn (TJ)

Institute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, Scotland, UK.

Alasdair G Rooney (AG)

Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburg, Edinburgh, Scotland, UK.

Eileen H Shinn (EH)

Department of Behavioral Science, University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

Abbey Sidebottom (A)

Allina Health, Minneapolis, MN, USA.

Lena Spangenberg (L)

Department of Medical Psychology and Medical Sociology, University of Leipzig, Leipzig, Germany.

Pei Lin Lynnette Tan (PLL)

Department of Psychological Medicine, Tan Tock Seng Hospital, Singapore.

Martin Taylor-Rowan (M)

Institute of Cardiovascular and Medical Science, University of Glasgow, Glasgow, Scotland, UK.

Alyna Turner (A)

School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia; Deakin University, IMPACT Strategic Research Centre, School of Medicine, Barwon Health, Geelong, Victoria, Australia.

Henk C van Weert (HC)

Department of General Practice, Amsterdam Institute for General Practice and Public Health, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands.

Paul A Vöhringer (PA)

Department of Psychiatry and Mental Health, Clinical Hospital, Universidad de Chile, Santiago, Chile; Millennium Institute for Depression and Personality Research (MIDAP), Ministry of Economy, Macul, Santiago, Chile; Psychiatry Department, Tufts Medical Center, Tufts University, Boston, MA, USA.

Lynne I Wagner (LI)

Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Wake Forest University, Winston-Salem, NC, USA; Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC, USA.

Jennifer White (J)

Department of Physiotherapy, School of Primary and Allied Health Care, Monash University, Melbourne, Australia.

Kirsty Winkley (K)

Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, London, UK.

Brett D Thombs (BD)

Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Québec, Canada; Department of Medicine, McGill University, Montréal, Québec, Canada; Department of Psychiatry, McGill University, Montréal, Québec, Canada; Department of Psychology, McGill University, Montréal, Québec, Canada; Department of Educational and Counselling Psychology, McGill University, Montréal, Québec, Canada; Biomedical Ethics Unit, McGill University, Montréal, Québec, Canada. Electronic address: brett.thombs@mcgill.ca.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adolescent › Patient Health Questionnaire-9 scores do not...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Patient Health Questionnaire-9 scores do not...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Patient Health Questionnaire-9 scores do not...
questionsmedicales.fr › Sciences de l'information › Mémorisation et recherche des informations › Bases de données comme sujet › Bases de données factuelles › Patient Health Questionnaire-9 scores do not...
questionsmedicales.fr › Comportement et mécanismes comportementaux › Émotions › Dépression › Patient Health Questionnaire-9 scores do not...
questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Vocabulaire contrôlé › Diagnostic and stastistical manual of mental disorders (USA) › Patient Health Questionnaire-9 scores do not...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Patient Health Questionnaire-9 scores do not...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Patient Health Questionnaire-9 scores do not...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Enquêtes et questionnaires › Questionnaire de santé du patient › Patient Health Questionnaire-9 scores do not...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Morbidité › Prévalence › Patient Health Questionnaire-9 scores do not...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Jeune adulte › Patient Health Questionnaire-9 scores do not...