Olfactory and Neuropsychological Functioning in Olfactory Reference Syndrome.
neuropsychology
obsessive-compulsive and related disorders
olfaction
olfactory reference disorder
olfactory reference syndrome
Journal
Psychosomatics
ISSN: 1545-7206
Titre abrégé: Psychosomatics
Pays: England
ID NLM: 0376506
Informations de publication
Date de publication:
Historique:
received:
08
07
2019
revised:
20
12
2019
accepted:
23
12
2019
pubmed:
29
2
2020
medline:
27
4
2021
entrez:
29
2
2020
Statut:
ppublish
Résumé
Olfactory reference syndrome (ORS) is an underrecognized, understudied, and often severe psychiatric disorder characterized by a prominent and distressing or impairing preoccupation with a false belief of emitting an offensive body odor. As this condition has only recently been recognized in the International Classification of Diseases (the 11th Edition), no empirical evidence exists about the underlying features and etiology of the disorder. To examine the neuropsychological and olfactory functioning of individuals with ORS and address whether there is central nervous system or sensory dysfunction associated with the condition. In this preliminary investigation, 9 consecutive participants with ORS completed a structured clinical interview and neuropsychological and olfaction evaluations. A proportion of individuals with ORS displayed deficits in aspects of cognitive functioning (i.e., processing speed, executive functioning, recognition memory bias for ORS-related words), olfaction functioning (i.e., odor detection and discrimination), and emotional processing. Based on these preliminary findings of cognitive, olfaction, and emotional processing deficits in individuals with ORS, further neuropsychological and olfaction studies are needed that better characterize this understudied patient group and address this study's limitations.
Sections du résumé
BACKGROUND
Olfactory reference syndrome (ORS) is an underrecognized, understudied, and often severe psychiatric disorder characterized by a prominent and distressing or impairing preoccupation with a false belief of emitting an offensive body odor. As this condition has only recently been recognized in the International Classification of Diseases (the 11th Edition), no empirical evidence exists about the underlying features and etiology of the disorder.
OBJECTIVE
To examine the neuropsychological and olfactory functioning of individuals with ORS and address whether there is central nervous system or sensory dysfunction associated with the condition.
METHODS
In this preliminary investigation, 9 consecutive participants with ORS completed a structured clinical interview and neuropsychological and olfaction evaluations.
RESULTS
A proportion of individuals with ORS displayed deficits in aspects of cognitive functioning (i.e., processing speed, executive functioning, recognition memory bias for ORS-related words), olfaction functioning (i.e., odor detection and discrimination), and emotional processing.
CONCLUSIONS
Based on these preliminary findings of cognitive, olfaction, and emotional processing deficits in individuals with ORS, further neuropsychological and olfaction studies are needed that better characterize this understudied patient group and address this study's limitations.
Identifiants
pubmed: 32107040
pii: S0033-3182(19)30266-X
doi: 10.1016/j.psym.2019.12.009
pmc: PMC7211111
mid: NIHMS1548378
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
261-267Subventions
Organisme : NIMH NIH HHS
ID : K24 MH063975
Pays : United States
Informations de copyright
Published by Elsevier Inc.
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