BMI Trajectories from Birth to 23 Years by Cardiometabolic Risks in Young Adulthood.
Journal
Obesity (Silver Spring, Md.)
ISSN: 1930-739X
Titre abrégé: Obesity (Silver Spring)
Pays: United States
ID NLM: 101264860
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
received:
22
05
2019
accepted:
05
01
2020
pubmed:
29
2
2020
medline:
10
9
2020
entrez:
29
2
2020
Statut:
ppublish
Résumé
The aim of this study was to investigate whether the level, rate, and acceleration of BMI growth differ according to the presence or absence of adult cardiometabolic (CM) risks. BMI was measured in 1,000 Chileans at nine time points from birth to 23 years, and metabolic syndrome and its components were assessed at young adulthood. BMI growth was analyzed in the following three developmental periods: birth to 6 months, 6 months to 5 years, and 5 to 23 years. Individuals with CM risks had a specific constellation of early-life growth (faster growth after infancy, lower BMI decline approaching age 5, absence of a definitive BMI nadir in early childhood, higher 5-year BMI) and distinct young adult growth (larger BMI increases from childhood to young adulthood and lower levels of expected growth deceleration approaching young adulthood). Those with CM risks also attained BMI ≥ 25 at significantly younger ages than those absent risks (metabolic syndrome: 12.3 years vs. 20.1 years; hyperglycemia: 13.1 years vs. 18.9 years; hypertension: 13.2 years vs. 19.4 years; hypertriglyceridemia: 14.3 years vs. 19.5 years; inflammation: 15.9 years vs. 20.6 years). Larger and faster increases in BMI and a failure of BMI growth to decline or decelerate at specific developmental periods distinguished individuals who would and would not have adult CM risks.
Identifiants
pubmed: 32108435
doi: 10.1002/oby.22754
pmc: PMC7093235
mid: NIHMS1549619
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
813-821Subventions
Organisme : Eunice Kennedy Shriver National Institute of Child Health and Human Development
ID : R03-HD-097295
Pays : International
Organisme : NHLBI NIH HHS
ID : R01-HL-088530
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32-HL-079891
Pays : United States
Organisme : NICHD NIH HHS
ID : R03 HD097295
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01-HD-033487
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL079891
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL088530
Pays : United States
Organisme : NICHD NIH HHS
ID : R01 HD033487
Pays : United States
Organisme : NIH HHS
Pays : United States
Informations de copyright
© 2020 The Obesity Society.
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