High hepatitis C virus infection among female sex workers in Viet Nam: strong correlation with HIV and injection drug use.
Journal
Western Pacific surveillance and response journal : WPSAR
ISSN: 2094-7313
Titre abrégé: Western Pac Surveill Response J
Pays: Philippines
ID NLM: 101558993
Informations de publication
Date de publication:
Historique:
entrez:
29
2
2020
pubmed:
29
2
2020
medline:
16
5
2020
Statut:
epublish
Résumé
The World Health Organization's guidelines on viral hepatitis testing and treatment recommend prioritizing high prevalence groups. Hepatitis C virus (HCV) infection disproportionately affects people who inject drugs and men who have sex with men, but data on female sex workers (FSW) are limited. The study aimed to determine active HCV infection and risk factors associated with HCV exposure among Vietnamese FSW. We surveyed 1886 women aged ≥ 18 years from Haiphong, Hanoi and Ho Chi Minh City who had sold sex in the last month. We tested for HCV antibody and HCV core antigen as markers for exposure to HCV and active infection, respectively. Across these provinces, high prevalence of HCV exposure (8.8-30.4%) and active infection (3.6-22.1%) were observed. Significant associations with HCV exposure were HIV infection (aOR = 23.7; 95% CI: 14.8-37.9), injection drug use (aOR = 23.3; 95% CI: 13.1-41.4), history of compulsory detention (aOR = 2.5; 95% CI: 1.4-4.2) and having more than 10 sex clients in the last month (aOR = 1.9; 95% CI: 1.2-3.2). Among FSW who reported never injecting drugs, HIV infection (aOR = 24.2; 95% CI: 14.8-39.4), a history of non-injection drug use (aOR = 3.3, CI: 1.8-5.7), compulsory detention (aOR = 2.2; 95% CI: 1.2-4.0) and having over 10 sex clients in the last month (aOR = 2.2, 95% CI: 1.3-3.7) were independently associated with HCV exposure. FSW have elevated HCV risks through sex- and drug-related pathways. These findings highlight the need to offer FSW-targeted HCV interventions and ensure their access to HIV prevention and treatment.
Identifiants
pubmed: 32110460
doi: 10.5365/wpsar.2019.10.1.002
pii: wpsar.2019.10.3-009
pmc: PMC7024697
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
9-18Informations de copyright
(c) 2019 The authors; licensee World Health Organization.
Références
J Gastroenterol Hepatol. 2007 Dec;22(12):2093-100
pubmed: 17645465
Int J Infect Dis. 2017 Feb;55:31-37
pubmed: 28027990
J Acquir Immune Defic Syndr. 2015 Jun 1;69 Suppl 2:S176-81
pubmed: 25978485
J Med Virol. 1993 Apr;39(4):312-7
pubmed: 8492103
Hepatology. 2013 Oct;58(4):1215-24
pubmed: 23504650
J Virol. 2003 Jun;77(12):6601-12
pubmed: 12767980
Curr Opin HIV AIDS. 2010 Jul;5(4):305-10
pubmed: 20543605
Am J Trop Med Hyg. 2003 Sep;69(3):288-94
pubmed: 14628946
Zhonghua Liu Xing Bing Xue Za Zhi. 1995 Aug;16(4):213-6
pubmed: 7585900
Reprod Health Matters. 2008 May;16(31):168-81
pubmed: 18513618
J Infect Dis. 1995 Apr;171(4):768-75
pubmed: 7535827
Int J Mol Med. 2007 Feb;19(2):293-9
pubmed: 17203204
Nat Rev Gastroenterol Hepatol. 2013 Sep;10(9):553-62
pubmed: 23817321
Int J Drug Policy. 2011 May;22(3):203-9
pubmed: 21316935
Trop Gastroenterol. 2006 Apr-Jun;27(2):80-3
pubmed: 17089617
Ann Intern Med. 2016 Sep 6;165(5):345-55
pubmed: 27322622
World J Gastroenterol. 2007 May 7;13(17):2436-41
pubmed: 17552026
Drug Alcohol Depend. 2015 May 1;150:46-53
pubmed: 25765480
Liver Int. 2011 Jul;31 Suppl 2:61-80
pubmed: 21651703
Lancet Infect Dis. 2016 Dec;16(12):1385-1398
pubmed: 27665254
PLoS One. 2015 Feb 18;10(2):e0118304
pubmed: 25692469
Clin Infect Dis. 2003 Aug 15;37(4):514-20
pubmed: 12905135
J Gastroenterol Hepatol. 2013 Jan;28(1):10-7
pubmed: 23094699
J Infect Dis. 2008 May 15;197 Suppl 3:S279-93
pubmed: 18447614
Sex Transm Infect. 2016 Nov;92(7):542-549
pubmed: 27044267
AIDS Behav. 2018 Jul;22(7):2161-2171
pubmed: 28612212