The Relationship Between Gastrointestinal Comorbidities, Clinical Presentation and Surgical Outcome in Patients with DCM: Analysis of a Global Cohort.
anterior
cervical spondylotic myelopathy (CSM)
multicenter
posterior
prospective
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
26 Feb 2020
26 Feb 2020
Historique:
received:
31
12
2019
revised:
14
02
2020
accepted:
18
02
2020
entrez:
1
3
2020
pubmed:
1
3
2020
medline:
1
3
2020
Statut:
epublish
Résumé
Degenerative cervical myelopathy (DCM) is the most common cause of spinal cord impairment in adults, presenting most frequently in patients 50 years or older. Gastrointestinal comorbidities (GICs) commonly occur in this group; however, their relationship with DCM has not been thoroughly investigated. It is the objective of the present study to investigate the difference between patients with or without GICs who are surgically treated for DCM. A cohort of 757 patients with clinical data and 458 with magnetic resonance imaging (MRI) data from the AOSpine North America and AOSpine International studies on DCM was evaluated. GICs were obtained at presentation and included gastric, intestinal, hepatic, and pancreatic conditions. Patients were dichotomized into 2 groups: those with GICs and those without GICs. Both clinical and MRI presentation, as well as baseline neurological and functional status, were compared. Neurological and functional outcomes at 2-year follow-up were also compared. GICs were present in 121 patients (16%). These patients were less commonly male (48.76% vs. 65.4%,
Identifiants
pubmed: 32110873
pii: jcm9030624
doi: 10.3390/jcm9030624
pmc: PMC7141130
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
No Shinkei Geka. 2016 Dec;44(12):1059-1063
pubmed: 27932751
J Spinal Disord. 1991 Sep;4(3):286-95
pubmed: 1802159
N Engl J Med. 2013 May 23;368(21):2041-2
pubmed: 23697526
Brain. 1972;95(1):87-100
pubmed: 5023093
Nat Rev Gastroenterol Hepatol. 2012 May 01;9(6):345-54
pubmed: 22547309
J Clin Neurosci. 2020 Feb;72:252-257
pubmed: 31911107
Neurosurgery. 2017 Jan 01;80(1):121-128
pubmed: 27607403
Spine J. 2012 Mar;12(3):197-206
pubmed: 22245448
Spine (Phila Pa 1976). 2009 Apr 20;34(9):890-5
pubmed: 19352222
Surg Neurol Int. 2017 Dec 27;8:307
pubmed: 29404194
Spine (Phila Pa 1976). 2017 Jul 15;42(14):1058-1067
pubmed: 27861250
Am J Med. 1992 Jan 24;92(1A):26S-30S
pubmed: 1531168
Psychosom Med. 2004 Nov-Dec;66(6):845-51
pubmed: 15564348
Global Spine J. 2017 Dec;7(8):787-793
pubmed: 29238644
Spine (Phila Pa 1976). 2017 Jul 1;42(13):979-983
pubmed: 27831968
Global Spine J. 2019 May;9(3):331-337
pubmed: 31192102
Spine (Phila Pa 1976). 2015 Jun 15;40(12):E675-93
pubmed: 25839387
World J Gastroenterol. 2007 May 14;13(18):2575-80
pubmed: 17552004
Eur J Haematol. 2013 Jan;90(1):1-9
pubmed: 23034053
J Gastroenterol Hepatol. 2019 Apr;34(4):713-719
pubmed: 29971822
Spine (Phila Pa 1976). 2017 Dec 15;42(24):1851-1858
pubmed: 28498290
Global Spine J. 2017 Aug;7(5):441-447
pubmed: 28811988
Lancet Neurol. 2006 Nov;5(11):949-60
pubmed: 17052662
Electromyogr Clin Neurophysiol. 2003 Oct-Nov;43(7):443-7
pubmed: 14626725
J Manipulative Physiol Ther. 1991 Sep;14(7):409-15
pubmed: 1834753
Neurol Sci. 2016 Sep;37(9):1577-8
pubmed: 27043950
Spine J. 2014 Feb 1;14(2):381-2
pubmed: 24295894
Med Care. 1992 Jun;30(6):473-83
pubmed: 1593914
CMAJ. 2004 Aug 3;171(3):251-9
pubmed: 15289425
Exp Ther Med. 2013 Oct;6(4):943-946
pubmed: 24137294
J Bone Joint Surg Am. 2013 Sep 18;95(18):1651-8
pubmed: 24048552
Spine (Phila Pa 1976). 2015 Sep 1;40(17):1322-8
pubmed: 26020847
Nat Rev Rheumatol. 2014 Sep;10(9):561-6
pubmed: 24914695
Spine (Phila Pa 1976). 2010 Mar 15;35(6):620-4
pubmed: 20150835
Front Mol Biosci. 2016 Jun 27;3:27
pubmed: 27446930