Toxicity, transfer and depuration of anatoxin-a (cyanobacterial neurotoxin) in medaka fish exposed by single-dose gavage.
Animals
Cyanobacteria
/ metabolism
Cyanobacteria Toxins
Eutrophication
Female
Gastrointestinal Tract
/ drug effects
Lethal Dose 50
Liver
/ drug effects
Marine Toxins
/ metabolism
Models, Theoretical
Muscles
/ drug effects
Neurotoxins
/ metabolism
No-Observed-Adverse-Effect Level
Oryzias
/ metabolism
Rivers
/ chemistry
Toxicokinetics
Tropanes
/ metabolism
Water Pollutants, Chemical
/ metabolism
Cyanobacteria
Fish
Gavage
Neurotoxin
Toxico-Kinetics
Toxicology
Journal
Aquatic toxicology (Amsterdam, Netherlands)
ISSN: 1879-1514
Titre abrégé: Aquat Toxicol
Pays: Netherlands
ID NLM: 8500246
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
received:
12
12
2019
revised:
15
01
2020
accepted:
21
01
2020
pubmed:
1
3
2020
medline:
22
5
2020
entrez:
1
3
2020
Statut:
ppublish
Résumé
The proliferations of cyanobacteria are increasingly prevalent in many rivers and water bodies due especially to eutrophication. This work aims to study in female medaka fish the toxicity, the transfer and the depuration of the anatoxin-a, a neurotoxin produced by benthic cyanobacterial biofilms. This work will provide answers regarding acute toxicity induced by single gavage by anatoxin-a and to the risks of exposure by ingestion of contaminated fish flesh, considering that data on these aspects remain particularly limited. The oral LD
Identifiants
pubmed: 32112996
pii: S0166-445X(19)31051-3
doi: 10.1016/j.aquatox.2020.105422
pii:
doi:
Substances chimiques
Cyanobacteria Toxins
0
Marine Toxins
0
Neurotoxins
0
Tropanes
0
Water Pollutants, Chemical
0
anatoxin a
80023A73NK
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
105422Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest None.