The characteristics of patients with bilateral absent evoked potentials after post-anoxic brain damage: A multicentric cohort study.


Journal

Resuscitation
ISSN: 1873-1570
Titre abrégé: Resuscitation
Pays: Ireland
ID NLM: 0332173

Informations de publication

Date de publication:
04 2020
Historique:
received: 15 12 2019
revised: 18 02 2020
accepted: 21 02 2020
pubmed: 3 3 2020
medline: 22 6 2021
entrez: 2 3 2020
Statut: ppublish

Résumé

Patients with bilateral absence of cortical response (N20 Retrospective analysis of institutional databases (2008-2015) in three ICUs including all adult admitted comatose patients undergoing SSEPs between 48 and 72 h after CA. We collected clinical (i.e. absence of pupillary reflexes, PLR, myoclonus and absent or posturing motor response and myoclonus on day 2-3), electroencephalographic (EEG; i.e. unreactive to painful stimuli; presence of a highly malignant patterns, such as burst-suppression or flat tracings) findings during the first 48 h, and the highest NSE levels on the first 3 days after CA. Unfavorable neurological outcome (UO) was assessed at 3 months using the Cerebral Performance Categories of 3-5. We studied 532 patients with SSEPs, including 143 (27%) without N20 Clinical and EEG findings predicting patients with N20

Identifiants

pubmed: 32114066
pii: S0300-9572(20)30083-6
doi: 10.1016/j.resuscitation.2020.02.017
pii:
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

134-140

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Auteurs

Leda Nobile (L)

Department of Intensive Care, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.

Erik Roman Pognuz (ER)

Department of Anesthesia and Intensive Care, Azienda Sanitaria Universitaria Integrata di Trieste (ASUITs), Italy.

Andrea O Rossetti (AO)

Department of Clinical Neurosciences, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.

Federico Franchi (F)

Department of Intensive Care, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.

Francesca Verginella (F)

Department of Anesthesia and Intensive Care, Azienda Sanitaria Universitaria Integrata di Trieste (ASUITs), Italy.

Nicolas Mavroudakis (N)

Department of Neurology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.

Jacques Creteur (J)

Department of Intensive Care, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.

Giorgio Berlot (G)

Department of Anesthesia and Intensive Care, Azienda Sanitaria Universitaria Integrata di Trieste (ASUITs), Italy.

Mauro Oddo (M)

Department of Intensive Care Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.

Fabio Silvio Taccone (FS)

Department of Intensive Care, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium. Electronic address: ftaccone@ulb.ac.be.

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