Signaling in the Physiology and Pathophysiology of Pancreatic Stellate Cells -
Hippo
PDAC
Wnt
calcium
pancreas
pancreatic cancer
pancreatic stellate cells
signaling
Journal
Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006
Informations de publication
Date de publication:
2020
2020
Historique:
received:
06
12
2019
accepted:
23
01
2020
entrez:
3
3
2020
pubmed:
3
3
2020
medline:
3
3
2020
Statut:
epublish
Résumé
The interest in pancreatic stellate cells (PSCs) has been steadily growing over the past two decades due mainly to the central role these cells have in the desmoplastic reaction associated with diseases of the pancreas, such as pancreatitis or pancreatic cancer. In recent years, the scientific community has devoted substantial efforts to understanding the signaling pathways that govern PSC activation and interactions with neoplastic cells. This mini review aims to summarize some very recent findings on signaling in PSCs and highlight their impact to the field.
Identifiants
pubmed: 32116785
doi: 10.3389/fphys.2020.00078
pmc: PMC7033654
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
78Informations de copyright
Copyright © 2020 Kusiak, Szopa, Jakubowska and Ferdek.
Références
Biophys Rev. 2018 Dec;10(6):1695-1711
pubmed: 30406572
Cell. 2007 Dec 14;131(6):1047-58
pubmed: 18083096
Sci Adv. 2019 Sep 04;5(9):eaax2770
pubmed: 31517053
J Biol Chem. 2000 Jan 28;275(4):2247-50
pubmed: 10644669
Clin Cancer Res. 2015 Aug 1;21(15):3561-8
pubmed: 25695692
Theranostics. 2019 Sep 23;9(24):7168-7183
pubmed: 31695760
Gene Expr. 2003;11(3-4):141-7
pubmed: 14686787
Am J Physiol Regul Integr Comp Physiol. 2013 May 1;304(9):R702-11
pubmed: 23447134
J Physiol. 2016 Jan 15;594(2):281-93
pubmed: 26442817
Nature. 2016 Aug 25;536(7617):479-83
pubmed: 27509858
J Cell Mol Med. 2019 Aug;23(8):5006-5016
pubmed: 31119886
Mol Biol Cell. 2011 Feb 1;22(3):421-36
pubmed: 21148289
Clin Cancer Res. 2014 Aug 15;20(16):4326-38
pubmed: 24947933
Cell Calcium. 2016 Mar;59(2-3):140-4
pubmed: 26960936
Annu Rev Physiol. 2008;70:273-99
pubmed: 17850212
Gut. 2006 Jan;55(1):79-89
pubmed: 16043492
Oncotarget. 2017 Sep 11;8(44):76722-76739
pubmed: 29100344
Biochem J. 2012 Jan 15;441(2):541-52
pubmed: 22187935
Cell Death Differ. 2018 Jan;25(1):81-92
pubmed: 28984872
Pancreatology. 2019 Mar;19(2):252-257
pubmed: 30792046
Biochem Biophys Res Commun. 2004 Oct 29;323(4):1241-5
pubmed: 15451430
Carcinogenesis. 2014 Aug;35(8):1891-900
pubmed: 24876152
Curr Opin Cell Biol. 2010 Apr;22(2):132-9
pubmed: 20056399
Cancer Res. 2011 Feb 1;71(3):1019-28
pubmed: 21148071
J Physiol. 2016 Nov 1;594(21):6147-6164
pubmed: 27406326
J Exp Med. 2017 Mar 6;214(3):579-596
pubmed: 28232471
Gastroenterology. 2015 Mar;148(3):626-638.e17
pubmed: 25497209
J Natl Cancer Inst. 2012 Oct 3;104(19):1470-84
pubmed: 22984202
Pancreas. 2015 Nov;44(8):1211-33
pubmed: 26465950
Clin Cancer Res. 2009 Dec 15;15(24):7462-7468
pubmed: 20008845
Nat Immunol. 2015 Oct;16(10):1014-24
pubmed: 26382870
Genes Cancer. 2018 Mar;9(3-4):78-86
pubmed: 30108679
EMBO Rep. 2019 Jan;20(1):
pubmed: 30538117
Gut. 2002 Oct;51(4):579-84
pubmed: 12235084
J Urol. 2014 May;191(5 Suppl):1508-16
pubmed: 24679864
J Pathol. 2000 Sep;192(1):81-9
pubmed: 10951404
Oncol Lett. 2019 Feb;17(2):2057-2062
pubmed: 30675272
Front Cell Dev Biol. 2019 Oct 04;7:199
pubmed: 31637239
PLoS One. 2014 Apr 18;9(4):e95145
pubmed: 24747916
Gastroenterology. 1998 Aug;115(2):421-32
pubmed: 9679048
Am J Surg. 1994 Feb;167(2):261-3
pubmed: 8135316
Adv Drug Deliv Rev. 2018 Apr;129:37-53
pubmed: 29414674
Life Sci. 2019 Jan 15;217:243-250
pubmed: 30550889
Biochem Biophys Res Commun. 2019 Jul 30;515(3):493-498
pubmed: 31171359
Clin Gastroenterol Hepatol. 2009 Nov;7(11 Suppl):S48-54
pubmed: 19896099
Pancreas. 2007 Apr;34(3):364-72
pubmed: 17414061
Cancer Res. 2009 Feb 15;69(4):1293-301
pubmed: 19176383
Trends Cell Biol. 2015 Sep;25(9):499-513
pubmed: 26045258
Clin Gastroenterol Hepatol. 2008 Oct;6(10):1155-61
pubmed: 18639493
Pancreas. 2003 Aug;27(2):150-60
pubmed: 12883264
Pflugers Arch. 2017 Sep;469(9):1039-1050
pubmed: 28382480
Cancer Cell. 2012 Mar 20;21(3):418-29
pubmed: 22439937
Biochem Pharmacol. 2004 Mar 15;67(6):1215-25
pubmed: 15006556
Pflugers Arch. 2017 Dec;469(12):1567-1577
pubmed: 28849300
EMBO Rep. 2019 Jan;20(1):
pubmed: 30538116
J Pathol. 2010 May;221(1):3-12
pubmed: 20225336
Cell. 2005 Sep 23;122(6):927-39
pubmed: 16179260
Gastroenterology. 2005 Apr;128(4):907-21
pubmed: 15825074
Gastroenterology. 2000 Apr;118(4):780-94
pubmed: 10734030
Cancer Lett. 2019 Oct 10;462:51-60
pubmed: 31352078
Am J Physiol Gastrointest Liver Physiol. 2008 Oct;295(4):G709-17
pubmed: 18669622
J Gastroenterol. 2009;44(4):249-60
pubmed: 19271115
Gastroenterology. 2005 Sep;129(3):1019-30
pubmed: 16143139
Gut. 2002 Apr;50(4):535-41
pubmed: 11889076
FASEB J. 2019 May;33(5):6609-6621
pubmed: 30808244
PLoS Biol. 2019 Sep 12;17(9):e3000418
pubmed: 31513574
J Biol Chem. 2004 Mar 5;279(10):8873-8
pubmed: 14688282
J Pathol. 2016 Jul;239(3):286-96
pubmed: 27061193
Cancers (Basel). 2012 Sep 06;4(3):873-903
pubmed: 24213471
Cell. 2014 Sep 25;159(1):80-93
pubmed: 25259922
Gastroenterology. 2017 May;152(6):1492-1506.e24
pubmed: 28126348
Open Biol. 2016 Aug;6(8):
pubmed: 27488376
World J Gastroenterol. 2018 Jan 14;24(2):170-178
pubmed: 29375203
Cell Calcium. 2018 Mar;70:32-46
pubmed: 28847414
Sci Rep. 2017 May 11;7(1):1787
pubmed: 28496202
Nature. 2019 May;569(7754):131-135
pubmed: 30996350
Gut. 2003 Feb;52(2):275-82
pubmed: 12524413
Mol Biol Cell. 2017 Nov 7;28(23):3134-3155
pubmed: 28954860
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
Eur Biophys J. 2016 Oct;45(7):657-670
pubmed: 27670661
Gut. 2013 Jan;62(1):112-20
pubmed: 22466618
Gut. 1999 Apr;44(4):534-41
pubmed: 10075961
Clin Cancer Res. 2016 Nov 15;22(22):5592-5604
pubmed: 27267855
Genes Dev. 2016 Jan 1;30(1):1-17
pubmed: 26728553
PLoS Med. 2005 Sep;2(9):e251
pubmed: 16128620
Gut. 1998 Jul;43(1):128-33
pubmed: 9771417
Cancer Res. 2018 Feb 15;78(4):909-921
pubmed: 29269518
J Biol Chem. 2002 Jan 4;277(1):141-7
pubmed: 11606585
Am J Pathol. 1999 Oct;155(4):1087-95
pubmed: 10514391