Prognostic Impact of Menopausal Hormone Therapy in Breast Cancer Differs According to Tumor Characteristics and Treatment.

aromatase inhibitor breast cancer cohort menopausal hormone therapy prognosis

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2020
Historique:
received: 22 10 2019
accepted: 16 01 2020
entrez: 3 3 2020
pubmed: 3 3 2020
medline: 3 3 2020
Statut: epublish

Résumé

This study investigated how a history of menopausal hormone therapy (MHT) impacts clinical outcomes overall and in different subgroups of breast cancer patients. The study included 814 primary breast cancer patients aged ≥50 years in Sweden (2002-2012) with follow-up until 2016. Associations between patient- and tumor characteristics, recurrences, and overall survival were analyzed in relation to MHT. After a median follow-up of 7 years, 119 recurrences, and 111 deaths occurred. Ever MHT (

Identifiants

pubmed: 32117735
doi: 10.3389/fonc.2020.00080
pmc: PMC7015974
doi:

Types de publication

Journal Article

Langues

eng

Pagination

80

Informations de copyright

Copyright © 2020 Godina, Ottander, Tryggvadottir, Borgquist, Isaksson and Jernström.

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Auteurs

Christopher Godina (C)

Department of Clinical Sciences in Lund, Division of Oncology and Pathology, Lund University and Skåne University Hospital, Lund, Sweden.

Erik Ottander (E)

Department of Clinical Sciences in Lund, Division of Oncology and Pathology, Lund University and Skåne University Hospital, Lund, Sweden.

Helga Tryggvadottir (H)

Department of Clinical Sciences in Lund, Division of Oncology and Pathology, Lund University and Skåne University Hospital, Lund, Sweden.

Signe Borgquist (S)

Department of Clinical Sciences in Lund, Division of Oncology and Pathology, Lund University and Skåne University Hospital, Lund, Sweden.
Department of Oncology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.

Karolin Isaksson (K)

Division of Surgery, Department of Clinical Sciences in Lund, Lund University and Skåne University Hospital, and Central Hospital Kristianstad, Lund, Sweden.

Helena Jernström (H)

Department of Clinical Sciences in Lund, Division of Oncology and Pathology, Lund University and Skåne University Hospital, Lund, Sweden.

Classifications MeSH