An active heteropolysaccharide from the rinds of Garcinia mangostana Linn.: Structural characterization and immunomodulation activity evaluation.

Animals Carbohydrate Conformation Garcinia mangostana / chemistry Immunomodulation Macrophages / immunology Mice Models, Immunological Nitric Oxide / immunology Particle Size Polysaccharides / chemistry RAW 264.7 Cells Reactive Oxygen Species / immunology Surface Properties Zebrafish
2', 7'-dichlorofluorescein diacetate (PubChem CID: 104913) 3-amino, 4-aminomethyl-2′, 7′-difluorescein diacetate (PubChem CID: 2762646) Acetic anhydride (PubChem CID: 7918) Congo red (PubChem CID: 11313) Garcinia mangostana Linn. Immunomodulation L-arabinose (PubChem CID: 439195) Macrophages Methyl iodide (PubChem CID: 6328) Neutral red (PubChem CID: 11105) Polysaccharide Potassium bromide (PubChem CID: 253877) Sodium borodeuteride (PubChem CID: 23673181) Trifluoroacetic acid (PubChem CID: 6422) Zebrafish embryo

Journal

Carbohydrate polymers
ISSN: 1879-1344
Titre abrégé: Carbohydr Polym
Pays: England
ID NLM: 8307156

Informations de publication

Date de publication:
01 May 2020
Historique:
received: 26 11 2019
revised: 17 01 2020
accepted: 27 01 2020
entrez: 4 3 2020
pubmed: 4 3 2020
medline: 27 10 2020
Statut: ppublish

Résumé

A previously undescribed polysaccharide, GMP70-1, was isolated from the rinds of Garcinia mangostana Lin. Physicochemical characterization analysis showed that GMP70-1 (absolute molecular weight: 2.01 × 10

Identifiants

DOI: 10.1016/j.carbpol.2020.115929 PMID: 32122475
pubmed: 32122475
pii: S0144-8617(20)30103-X
doi: 10.1016/j.carbpol.2020.115929
pii:
doi:

Substances chimiques

Polysaccharides 0
Reactive Oxygen Species 0
Nitric Oxide 31C4KY9ESH

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

115929

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors have no conflicts of interest.

Auteurs

Shaojie Zhang (S)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China.

Lijun An (L)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China.

Zhengguo Li (Z)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China.

Honglin Wang (H)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China.

Lijuan Shi (L)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China.

Jie Zhang (J)

Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, School of Chemistry and Chemical Engineering, Shihezi University, Shihezi, 832003, People's Republic of China.

Yuhao Li (Y)

School of Medicine, Nankai University, Tianjin, 300071, People's Republic of China.

Da-Qing Jin (DQ)

School of Medicine, Nankai University, Tianjin, 300071, People's Republic of China.

Muhetaer Tuerhong (M)

College of Chemistry and Environmental Sciences, Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry, Kashgar University, Kashgar, 844000, People's Republic of China.

Yasushi Ohizumi (Y)

Kansei Fukushi Research Institute, Tohoku Fukushi University, Sendai, 989-3201, Japan.

Ling Shuai (L)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China.

Jing Xu (J)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin, 541004, People's Republic of China. Electronic address: xujing611@nankai.edu.cn.

Yuanqiang Guo (Y)

State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Tianjin Key Laboratory of Molecular Drug Research, and Drug Discovery Center for Infectious Disease, Nankai University, Tianjin, 300350, People's Republic of China. Electronic address: victgyq@nankai.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des glucides › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Rosanae › Clusiaceae › Garcinia › Garcinia mangostana › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunomodulation › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles immunologiques › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Oxydes d'azote › Monoxyde d'azote › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Phénomènes chimiques › Taille de particule › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Glucides › Polyosides › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Cellules › Cellules RAW 264.7 › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Espèces réactives de l'oxygène › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Phénomènes chimiques › Propriétés de surface › An active heteropolysaccharide from the rinds...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Cypriniformes › Cyprinidae › Danio zébré › An active heteropolysaccharide from the rinds...