Environmental risk assessment of diclofenac residues in surface waters and wastewater: a hidden global threat to aquatic ecosystem.
Diclofenac
Ecological risk assessment
Non-steroidal anti-inflammatory drug
Pharmaceutical
Solid-phase extraction
Journal
Environmental monitoring and assessment
ISSN: 1573-2959
Titre abrégé: Environ Monit Assess
Pays: Netherlands
ID NLM: 8508350
Informations de publication
Date de publication:
02 Mar 2020
02 Mar 2020
Historique:
received:
19
09
2019
accepted:
10
02
2020
entrez:
4
3
2020
pubmed:
4
3
2020
medline:
14
3
2020
Statut:
epublish
Résumé
Pharmaceuticals are chemical compounds employed as medicinal drugs. They have severe physic-chemical properties which make them destructive for non-target species. Consequently, their continuous addition in the environment may pose hazardous effects. Among these, diclofenac (DCF), a non-steroidal anti-inflammatory drug (NSAID), is extensively used in Pakistan which may lead to its accumulation in both terrestrial and aquatic environment. Present study aims to assess the presence and concentration of pharmaceutically active drug (DCF) in surface water and wastewater of twin cities of Pakistan (Rawalpindi and Islamabad). For this purpose, a validated high-performance liquid chromatography (HPLC) method was adopted involving solid-phase extraction procedure. Wastewater samples were collected from various sites of Rawalpindi and Islamabad. Results of HPLC analysis revealed that DCF was extant with considerably high concentration, not only in wastewater but also in surface water samples. Concentrations as high as 216 μg L
Identifiants
pubmed: 32124056
doi: 10.1007/s10661-020-8151-3
pii: 10.1007/s10661-020-8151-3
doi:
Substances chimiques
Pharmaceutical Preparations
0
Waste Water
0
Water Pollutants, Chemical
0
Diclofenac
144O8QL0L1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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