The effect of gender and ABCB1 gene polymorphism on the pharmacokinetics of azithromycin in healthy male and female Pakistani subjects.
ABCB1
différences entre les sexes
gender differences
gene polymorphism
pharmacocinétique
pharmacokinetics
polymorphisme génique
Journal
Canadian journal of physiology and pharmacology
ISSN: 1205-7541
Titre abrégé: Can J Physiol Pharmacol
Pays: Canada
ID NLM: 0372712
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
pubmed:
4
3
2020
medline:
4
6
2021
entrez:
4
3
2020
Statut:
ppublish
Résumé
In the current study, the possible outcome of gender difference and genotypic polymorphism of the ABCB1 gene encoding P-glycoprotein on the pharmacokinetics of azithromycin has been evaluated. An open-label, comparative pharmacokinetic study was done in healthy Pakistani volunteers (females (
Identifiants
pubmed: 32125889
doi: 10.1139/cjpp-2019-0569
doi:
Substances chimiques
ATP Binding Cassette Transporter, Subfamily B, Member 1
0
Azithromycin
83905-01-5
Types de publication
Clinical Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM