Evaluation of selected pharmaceuticals and personal care products in water matrix using ion trap mass spectrometry: A simple weighted calibration curve approach.
Anti-Bacterial Agents
/ analysis
Anti-Inflammatory Agents, Non-Steroidal
/ analysis
Calibration
Chromatography, High Pressure Liquid
/ methods
Chromatography, Reverse-Phase
/ methods
Cosmetics
/ analysis
Environmental Monitoring
/ methods
India
Limit of Detection
Parabens
/ analysis
Plasticizers
/ analysis
Rivers
Solid Phase Extraction
/ methods
Tandem Mass Spectrometry
/ methods
Water
/ analysis
Water Pollutants, Chemical
/ analysis
Water Pollution, Chemical
/ prevention & control
Arkavathi river
Bengaluru
Oasis HLB
PPCPs
Tandem-Mass spectrometer
Weighting model
Journal
Journal of pharmaceutical and biomedical analysis
ISSN: 1873-264X
Titre abrégé: J Pharm Biomed Anal
Pays: England
ID NLM: 8309336
Informations de publication
Date de publication:
05 Jun 2020
05 Jun 2020
Historique:
received:
23
01
2020
revised:
25
02
2020
accepted:
26
02
2020
pubmed:
4
3
2020
medline:
2
3
2021
entrez:
4
3
2020
Statut:
ppublish
Résumé
A novel analytical method is presented for 12 target pharmaceutical and personal care products (PPCPs), belonging to different classes like antibiotics, non-steroid anti-inflammatory drugs, parabens, UV-filters, plasticizer, and antibacterials. The method development comprises of solid-phase extraction (SPE) with lipophilic-hydrophilic material balanced Oasis HLB cartridge, followed by reverse-phase liquid chromatography interfaced to linear ion trap tandem mass spectrometry (LC-MS/MS) with electrospray ionization. Chromatographic separation was achieved with a gradient elution of 25 min run time using 5 mM ammonium acetate buffer with pH adjustment using acetic acid. In addition, cost effective organic solvent with buffer used together as the mobile phase with Chromatopak C
Identifiants
pubmed: 32126444
pii: S0731-7085(20)30199-0
doi: 10.1016/j.jpba.2020.113214
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Anti-Inflammatory Agents, Non-Steroidal
0
Cosmetics
0
Parabens
0
Plasticizers
0
Water Pollutants, Chemical
0
Water
059QF0KO0R
Types de publication
Journal Article
Validation Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
113214Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest No conflict of interest was reported by the authors.