Temporal bone histopathology: Superior semicircular canal dehiscence.

Superior semicircular canal dehiscence histopathology

Journal

Laryngoscope investigative otolaryngology
ISSN: 2378-8038
Titre abrégé: Laryngoscope Investig Otolaryngol
Pays: United States
ID NLM: 101684963

Informations de publication

Date de publication:
Feb 2020
Historique:
received: 18 06 2019
accepted: 03 11 2019
entrez: 5 3 2020
pubmed: 5 3 2020
medline: 5 3 2020
Statut: epublish

Résumé

To present a histopathological case of a 91-year-old woman who was diagnosed with superior semicircular canal dehiscence postmortem. The patient was a registered donor with the National Temporal Bone Donor Program at the NIDCD National Temporal Bone, Hearing and Balance Pathology Resource Registry. Computed tomography imaging was performed on each temporal bone. The temporal bones were decalcified with ethylenediaminetetracetate and embedded in celloidin, and tissue sections were stained with hematoxylin and eosin. Horizontal sections were taken through the left temporal bone, and vertical sections were taken through the right temporal bone. Histopathological sections taken through the right temporal bone demonstrated no bone between the membranous wall of the superior semicircular canal and the middle fossa dura. There was no histopathological evidence of superior semicircular canal dehiscence in the left temporal bone; however, a small dehiscence would not be identified on horizontal sections. Microcavitations were observed in the common crus of the left temporal bone. This reports describes the case of a woman who was diagnosed with superior semicircular canal dehiscence postmortem. The presence of microcavitations in the temporal bone is consistent with osteoclastic activity, which may play a role in the development of superior canal dehiscence.

Identifiants

pubmed: 32128437
doi: 10.1002/lio2.332
pii: LIO2332
pmc: PMC7042660
doi:

Types de publication

Journal Article

Langues

eng

Pagination

117-121

Informations de copyright

© 2019 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society.

Déclaration de conflit d'intérêts

None declared.

Références

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Ann Otol Rhinol Laryngol. 2012 Jan;121(1):7-12
pubmed: 22312921
Audiol Neurootol. 2017;22(4-5):218-225
pubmed: 29224005
Arch Otolaryngol Head Neck Surg. 1998 Mar;124(3):249-58
pubmed: 9525507

Auteurs

Brian M Lin (BM)

Department of Otolaryngology-Head and Neck Surgery Massachusetts Eye and Ear Boston Massachusetts.
Department of Otolaryngology-Head and Neck Surgery Harvard Medical School Boston Massachusetts.

Katherine Reinshagen (K)

Department of Otolaryngology-Head and Neck Surgery Harvard Medical School Boston Massachusetts.
Department of Radiology Massachusetts Eye and Ear Boston Massachusetts.

Joseph Nadol (J)

Department of Otolaryngology-Head and Neck Surgery Massachusetts Eye and Ear Boston Massachusetts.
Department of Otolaryngology-Head and Neck Surgery Harvard Medical School Boston Massachusetts.

Alicia M Quesnel (AM)

Department of Otolaryngology-Head and Neck Surgery Massachusetts Eye and Ear Boston Massachusetts.
Department of Otolaryngology-Head and Neck Surgery Harvard Medical School Boston Massachusetts.

Classifications MeSH