Design, Synthesis, Computational, and Preclinical Evaluation of


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
02 Mar 2020
Historique:
received: 31 01 2020
revised: 27 02 2020
accepted: 28 02 2020
entrez: 6 3 2020
pubmed: 7 3 2020
medline: 15 12 2020
Statut: epublish

Résumé

Despite promising anti-cancer properties in vitro, all titanium-based pharmaceuticals have failed in vivo. Likewise, no target-specific positron emission tomography (PET) tracer based on the radionuclide

Identifiants

pubmed: 32131399
pii: molecules25051104
doi: 10.3390/molecules25051104
pmc: PMC7179113
pii:
doi:

Substances chimiques

Pyridones 0
Radioactive Tracers 0
Radiopharmaceuticals 0
chelidamic acid 138-60-3
Glutamic Acid 3KX376GY7L
Urea 8W8T17847W
Titanium D1JT611TNE
KLK3 protein, human EC 3.4.21.-
Kallikreins EC 3.4.21.-
Prostate-Specific Antigen EC 3.4.21.77

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

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Coord Chem Rev. 2018 May 15;363:109-125
pubmed: 30270932
Chem Commun (Camb). 2012 Jun 11;48(46):5790-2
pubmed: 22549385
EJNMMI Res. 2018 Aug 22;8(1):84
pubmed: 30136051
J Med Chem. 2015 Sep 24;58(18):7591-5
pubmed: 26312993
Acta Pharmacol Sin. 2017 Jun;38(6):907-913
pubmed: 28414201
Semin Nucl Med. 1998 Jul;28(3):213-20
pubmed: 9704363
Nucl Med Biol. 2005 Feb;32(2):117-22
pubmed: 15721756
J Med Imaging (Bellingham). 2017 Jan;4(1):011013
pubmed: 28401173
Inorg Chem. 2016 Sep 19;55(18):9461-70
pubmed: 27580183
Inorg Chem. 2017 Jul 17;56(14):7788-7802
pubmed: 28644630
Nucl Med Mol Imaging. 2019 Apr;53(2):115-124
pubmed: 31057683
J Nucl Med. 2018 Nov;59(11):1655-1659
pubmed: 30262514
J Med Chem. 2009 Jan 22;52(2):347-57
pubmed: 19111054

Auteurs

Kristina Søborg Pedersen (K)

Department of Health Technology, Technical University of Denmark, Frederiksborgvej 399, Building 202, 4000 Roskilde, Denmark.

Christina Baun (C)

Department of Clinical Research, University of Southern Denmark, Sønder Boulevard 29, DK-5000 Odense, Denmark.
Department of Nuclear Medicine, Odense University Hospital, DK-5000 Odense, Denmark.

Karin Michaelsen Nielsen (K)

Department of Health Technology, Technical University of Denmark, Frederiksborgvej 399, Building 202, 4000 Roskilde, Denmark.

Helge Thisgaard (H)

Department of Clinical Research, University of Southern Denmark, Sønder Boulevard 29, DK-5000 Odense, Denmark.
Department of Nuclear Medicine, Odense University Hospital, DK-5000 Odense, Denmark.

Andreas Ingemann Jensen (A)

Department of Health Technology, Technical University of Denmark, Frederiksborgvej 399, Building 202, 4000 Roskilde, Denmark.

Fedor Zhuravlev (F)

Department of Health Technology, Technical University of Denmark, Frederiksborgvej 399, Building 202, 4000 Roskilde, Denmark.

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Classifications MeSH