Dental and craniofacial defects in the Crtap


Journal

Developmental dynamics : an official publication of the American Association of Anatomists
ISSN: 1097-0177
Titre abrégé: Dev Dyn
Pays: United States
ID NLM: 9201927

Informations de publication

Date de publication:
07 2020
Historique:
received: 20 11 2019
revised: 14 02 2020
accepted: 25 02 2020
pubmed: 7 3 2020
medline: 31 8 2021
entrez: 6 3 2020
Statut: ppublish

Résumé

Inactivating mutations in the gene for cartilage-associated protein (CRTAP) cause osteogenesis imperfecta type VII in humans, with a phenotype that can include craniofacial defects. Dental and craniofacial manifestations have not been a focus of case reports to date. We analyzed the craniofacial and dental phenotype of Crtap Crtap Crtap

Sections du résumé

BACKGROUND
Inactivating mutations in the gene for cartilage-associated protein (CRTAP) cause osteogenesis imperfecta type VII in humans, with a phenotype that can include craniofacial defects. Dental and craniofacial manifestations have not been a focus of case reports to date. We analyzed the craniofacial and dental phenotype of Crtap
RESULTS
Crtap
CONCLUSIONS
Crtap

Identifiants

pubmed: 32133710
doi: 10.1002/dvdy.166
pmc: PMC7727892
mid: NIHMS1574817
doi:

Substances chimiques

Crtap protein, mouse 0
Extracellular Matrix Proteins 0
Molecular Chaperones 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

884-897

Subventions

Organisme : NIDCR NIH HHS
ID : DE025827
Pays : United States
Organisme : NIGMS NIH HHS
ID : P20 GM125503
Pays : United States
Organisme : NIAMS NIH HHS
ID : AR069620
Pays : United States
Organisme : NIAMS NIH HHS
ID : AR066110
Pays : United States
Organisme : NIAMS NIH HHS
ID : R00 AR066110
Pays : United States
Organisme : NIAMS NIH HHS
ID : P30 AR069620
Pays : United States
Organisme : NIGMS NIH HHS
ID : GM125503
Pays : United States
Organisme : NIDCR NIH HHS
ID : R01 DE027639
Pays : United States
Organisme : NIDCR NIH HHS
ID : R01 DE025827
Pays : United States
Organisme : NIAMS NIH HHS
ID : R01 AR060823
Pays : United States
Organisme : NIDCR NIH HHS
ID : DE027639
Pays : United States
Organisme : NIAMS NIH HHS
ID : AR060823
Pays : United States
Organisme : NIAMS NIH HHS
ID : Intramural Research Program
Pays : United States

Informations de copyright

© 2020 Wiley Periodicals, Inc.

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Auteurs

He Xu (H)

Department of Pediatric Dentistry, Peking University and School and Hospital of Stomatology, Beijing, China.
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, Maryland, USA.

Sydney A Lenhart (SA)

Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, Michigan, USA.

Emily Y Chu (EY)

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, Maryland, USA.

Michael B Chavez (MB)

Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, Ohio, USA.

Helen F Wimer (HF)

Department of Vertebrate Zoology, National Museum of Natural History, Smithsonian Institution, Washington, District of Columbia, USA.
National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA.

Milena Dimori (M)

Department of Physiology & Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

Martha J Somerman (MJ)

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, Maryland, USA.

Roy Morello (R)

Department of Physiology & Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Department of Orthopaedic Surgery, Center for Orthopaedic Research, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Division of Genetics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

Brian L Foster (BL)

Division of Biosciences, College of Dentistry, The Ohio State University, Columbus, Ohio, USA.

Nan E Hatch (NE)

Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of Michigan, Ann Arbor, Michigan, USA.

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