Functional activities of beta-glucans in the prevention or treatment of cervical cancer.


Journal

Journal of ovarian research
ISSN: 1757-2215
Titre abrégé: J Ovarian Res
Pays: England
ID NLM: 101474849

Informations de publication

Date de publication:
05 Mar 2020
Historique:
received: 22 07 2019
accepted: 20 02 2020
entrez: 7 3 2020
pubmed: 7 3 2020
medline: 21 10 2020
Statut: epublish

Résumé

Cervical cancer is the fourth-ranked cancer in the world and is associated with a large number of deaths annually. Chemotherapy and radiotherapy are known as the common therapeutic approaches in the treatment of cervical cancer, but because of their side effects and toxicity, researchers are trying to discovery alternative therapies. Beta-glucans, a group of glucose polymers that are derived from the cell wall of fungi, bacteria, and etc. it has been showed that beta-glucans have some anti-cancer properties which due to their impacts on adaptive and innate immunity. Along to these impacts, these molecules could be used as drug carriers. In this regard, the application of beta-glucans is a promising therapeutic option for the cancer prevention and treatment especially for cervical cancer. Herein, we have summarized the therapeutic potential of beta-glucans alone or as adjuvant therapy in the treatment of cervical cancer. Moreover, we highlighted beta-glucans as drug carriers for preventive and therapeutic purposes.

Identifiants

pubmed: 32138756
doi: 10.1186/s13048-020-00626-7
pii: 10.1186/s13048-020-00626-7
pmc: PMC7057557
doi:

Substances chimiques

Carrier Proteins 0
beta-Glucans 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

24

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Auteurs

Shahla Chaichian (S)

Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran.

Bahram Moazzami (B)

Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran.

Fatemeh Sadoughi (F)

Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, I.R, Iran. rahasadoughi@gmail.com.

Hamed Haddad Kashani (H)

Anatomical Sciences Research Center, Kashan University of Medical Sciences, Kashan, Iran.

Marsa Zaroudi (M)

Student Research Committee, Faculty of Public Health Branch, Iran University of Medical Sciences, Tehran, Iran.

Zatollah Asemi (Z)

Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, I.R, Iran. asemi_r@yahoo.com.

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