The Transcription Factor Promyelocytic Leukemia Zinc Finger Protein Is Associated With Expression of Liver-Homing Receptors on Human Blood CD56


Journal

Hepatology communications
ISSN: 2471-254X
Titre abrégé: Hepatol Commun
Pays: United States
ID NLM: 101695860

Informations de publication

Date de publication:
Mar 2020
Historique:
received: 20 08 2019
accepted: 03 12 2019
entrez: 7 3 2020
pubmed: 7 3 2020
medline: 7 3 2020
Statut: epublish

Résumé

The transcription factor promyelocytic leukemia zinc finger protein (PLZF) is involved in the development of natural killer (NK) cells and innate lymphoid cells, including liver-resident NK cells in mice. In human NK cells, the role of PLZF in liver residency is still unknown. Expression of PLZF in matched human peripheral blood- and liver-derived NK cells and the association of PLZF expression with surface molecules and transcription factors relevant for tissue residency were investigated using multiparameter flow cytometry and assessing single-cell messenger RNA (mRNA) levels. Intrahepatic cluster of differentiation (CD)56

Identifiants

pubmed: 32140657
doi: 10.1002/hep4.1463
pii: HEP41463
pmc: PMC7049682
doi:

Types de publication

Journal Article

Langues

eng

Pagination

409-424

Informations de copyright

© 2020 The Authors. Hepatology Communications published by Wiley Periodicals, Inc., on behalf of the American Association for the Study of Liver Diseases.

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Auteurs

Leonard U Hess (LU)

Research Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.

Glòria Martrus (G)

Research Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.

Annerose E Ziegler (AE)

Research Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.

Annika E Langeneckert (AE)

Research Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.

Wilhelm Salzberger (W)

Research Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.

Hanna Goebels (H)

Research Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.

Adrian F Sagebiel (AF)

Research Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.

Sven H Hagen (SH)

Research Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.

Tobias Poch (T)

First Medical Clinic and Polyclinic Center for Internal Medicine University Medical Center Hamburg-Eppendorf Hamburg Germany.

Gevitha Ravichandran (G)

Institute of Experimental Immunology and Hepatology University Medical Center Hamburg-Eppendorf Hamburg Germany.

Martina Koch (M)

Division of Transplantation Surgery University Medical Center of the Johannes Gutenberg University Mainz Germany.

Christoph Schramm (C)

First Medical Clinic and Polyclinic Center for Internal Medicine University Medical Center Hamburg-Eppendorf Hamburg Germany.
Martin Zeitz Center for Rare Diseases University Medical Center Hamburg-Eppendorf Hamburg Germany.

Karl J Oldhafer (KJ)

Department of General and Abdominal Surgery Asklepios Hospital Barmbek Semmelweis University of Medicine Asklepios Campus Hamburg Germany.

Lutz Fischer (L)

Department of Hepatobiliary Surgery and Transplant Surgery University Medical Center Hamburg-Eppendorf Hamburg Germany.

Gisa Tiegs (G)

Institute of Experimental Immunology and Hepatology University Medical Center Hamburg-Eppendorf Hamburg Germany.

Laura Richert (L)

Research Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
University of Bordeaux Institut National de la Santé et de la Recherche Médicale Bordeaux Population Health Research Center UMR1219 and Inria, Team SISTM Bordeaux France.

Madeleine J Bunders (MJ)

Research Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.

Sebastian Lunemann (S)

Research Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.

Marcus Altfeld (M)

Research Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.

Classifications MeSH