Impact of lumbar pedicle screw positioning on screw stability - A biomechanical investigation.


Journal

Clinical biomechanics (Bristol, Avon)
ISSN: 1879-1271
Titre abrégé: Clin Biomech (Bristol, Avon)
Pays: England
ID NLM: 8611877

Informations de publication

Date de publication:
04 2020
Historique:
received: 08 09 2019
revised: 20 02 2020
accepted: 25 02 2020
pubmed: 8 3 2020
medline: 20 2 2021
entrez: 8 3 2020
Statut: ppublish

Résumé

Screw loosening is a major complication following spondylodesis. While several modifications increase screw stability, some, such as screw augmentation, are associated with potential complications; new techniques are needed to minimize the risk of screw loosening without increasing complication rates. 13 fresh-frozen human lumbar vertebral bodies (L1 to L5) were dissected. In group 1 (n = 7), pedicle screws were implanted conventionally, while in group 2 (n = 6), the screws were positioned divergent in the sagittal pathway. Screw stability was tested under cyclic axial load; one testing-cycle included 1000 repetitions. The first cycle started with a load of 100 N while the load was increased by +20 N in each following cycle until failure. Failure was defined by either a >5 mm movement of the screw heads or triggering of the switch-off threshold. Average number of cycles until failure was increased in group 2 compared with group 1 (12,046 vs 9761 cycles), as was the average load to failure (Fmax 313 N vs 260 N). Overall, in group 2, the number of cycles until screw loosening or failure increased by 23% (p = 0.28), while the required force increased by 20% (p = 0.3). Statistically significant correlation between BMD and increased number of cycles completed as well as with increased load (p < 0.01) could be observed. The results demonstrate, that divergent screw-drift of pairs of screws in the sagittal plane tends to increase stability, especially in vertebral bodies with lower bone density. Moreover, we could demonstrate a correlation between BMD and stability of screw-fixation.

Sections du résumé

BACKGROUND
Screw loosening is a major complication following spondylodesis. While several modifications increase screw stability, some, such as screw augmentation, are associated with potential complications; new techniques are needed to minimize the risk of screw loosening without increasing complication rates.
METHODS
13 fresh-frozen human lumbar vertebral bodies (L1 to L5) were dissected. In group 1 (n = 7), pedicle screws were implanted conventionally, while in group 2 (n = 6), the screws were positioned divergent in the sagittal pathway. Screw stability was tested under cyclic axial load; one testing-cycle included 1000 repetitions. The first cycle started with a load of 100 N while the load was increased by +20 N in each following cycle until failure. Failure was defined by either a >5 mm movement of the screw heads or triggering of the switch-off threshold.
FINDINGS
Average number of cycles until failure was increased in group 2 compared with group 1 (12,046 vs 9761 cycles), as was the average load to failure (Fmax 313 N vs 260 N). Overall, in group 2, the number of cycles until screw loosening or failure increased by 23% (p = 0.28), while the required force increased by 20% (p = 0.3). Statistically significant correlation between BMD and increased number of cycles completed as well as with increased load (p < 0.01) could be observed.
INTERPRETATION
The results demonstrate, that divergent screw-drift of pairs of screws in the sagittal plane tends to increase stability, especially in vertebral bodies with lower bone density. Moreover, we could demonstrate a correlation between BMD and stability of screw-fixation.

Identifiants

pubmed: 32145671
pii: S0268-0033(20)30077-2
doi: 10.1016/j.clinbiomech.2020.02.013
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

66-72

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Auteurs

David Grevenstein (D)

Department for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Joseph-Stelzmann Strasse 24, 50931 Cologne, Germany. Electronic address: david.grevenstein@uk-koeln.de.

Max J Scheyerer (MJ)

Department for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Joseph-Stelzmann Strasse 24, 50931 Cologne, Germany. Electronic address: max.scheyerer@uk-koeln.de.

Carolin Meyer (C)

Department for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Joseph-Stelzmann Strasse 24, 50931 Cologne, Germany. Electronic address: carolin.meyer@uk-koeln.de.

Jan Borggrefe (J)

Department for Diagnostic and Interventional Radiology, Faculty of Medicine, University Hospital of Cologne, Kerpener Strasse 62, 50937 Cologne, Germany. Electronic address: jan.borggrefe@uk-koeln.de.

Michael Hackl (M)

Department for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Joseph-Stelzmann Strasse 24, 50931 Cologne, Germany. Electronic address: michael.hackl@uk-koeln.de.

Stavros Oikonomidis (S)

Department for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Joseph-Stelzmann Strasse 24, 50931 Cologne, Germany. Electronic address: stavros.oikonomidis@uk-koeln.de.

Peer Eysel (P)

Department for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Joseph-Stelzmann Strasse 24, 50931 Cologne, Germany. Electronic address: peer.eysel@uk-koeln.de.

Andreas Prescher (A)

Institute of Molecular and Cellular Anatomy, University Hospital Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany. Electronic address: aprescher@ukaachen.de.

Kilian Wegmann (K)

Department for Orthopaedic and Trauma Surgery, Faculty of Medicine, University Hospital of Cologne, Joseph-Stelzmann Strasse 24, 50931 Cologne, Germany. Electronic address: kilian.wegmann@uk-koeln.de.

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