Psoriasis Induced by Biological Therapy.
Psoriasis inducida por terapia biológica.
Biological drugs
Chronic inflammatory disease
Enfermedad inflamatoria crónica
Fármacos biológicos
Paradoxical psoriasis
Psoriasis paradójica
Journal
Reumatologia clinica
ISSN: 2173-5743
Titre abrégé: Reumatol Clin (Engl Ed)
Pays: Spain
ID NLM: 101717526
Informations de publication
Date de publication:
04 Mar 2020
04 Mar 2020
Historique:
received:
24
09
2019
revised:
11
12
2019
accepted:
26
12
2019
entrez:
9
3
2020
pubmed:
9
3
2020
medline:
9
3
2020
Statut:
aheadofprint
Résumé
To describe a multicentre case series of new onset or worsening of psoriasis in patients treated with biological drugs. Descriptive study. We reviewed the clinical history of patients with chronic inflammatory disease (CID) treated with biological drugs, who developed new onset or worsening of psoriasis during the follow-up period. Twenty-six cases of paradoxical psoriasis (PP) were recorded. Ninety-three percent of the patients were treated with anti-TNFα and adalimumab was responsible for 50% of the cases. Only 5 patients had a personal history of psoriasis. The biological drug was discontinued in 13 patients. Lesion recurrence was more frequent when another anti-TNFα was reintroduced. The PP is a reversible adverse effect that can be observed in patients exposed to biological drugs, mainly anti-TNFα.
Identifiants
pubmed: 32146077
pii: S1699-258X(20)30019-X
doi: 10.1016/j.reuma.2019.12.005
pii:
doi:
Types de publication
Case Reports
Langues
eng
spa
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2020 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved.