Efficacy and Safety of Efinaconazole 10% Solution in the Treatment of Onychomycosis in Diabetic Patients.
Antifungal
Diabetes
Efinaconazole
Onychomycosis
Topical
Journal
Clinics in podiatric medicine and surgery
ISSN: 1558-2302
Titre abrégé: Clin Podiatr Med Surg
Pays: United States
ID NLM: 8604974
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
entrez:
10
3
2020
pubmed:
10
3
2020
medline:
22
9
2020
Statut:
ppublish
Résumé
Onychomycosis is especially common among diabetic patients. The purpose of this study was to investigate the efficacy of 10% efinaconazole solution among diabetic subjects, without restriction by nail plate involvement or glycemic control. Forty subjects were enrolled, with 36 reaching their final 50-week follow-up visit. Mycological cure was attained by 21 subjects (58.33%); 8 subjects (20%) attained either clinical cure (0% clinical involvement) or treatment success (≤10% clinical involvement). Glycemic control did not affect clinical outcome. The medication was well tolerated, with 4 local adverse events and no significant adverse events. The medication may represent a useful option for diabetic patients.
Identifiants
pubmed: 32146992
pii: S0891-8422(19)30110-7
doi: 10.1016/j.cpm.2019.12.015
pii:
doi:
Substances chimiques
Antifungal Agents
0
Blood Glucose
0
Triazoles
0
efinaconazole
J82SB7FXWB
Types de publication
Clinical Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
401-407Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosure The authors have nothing to disclose.