Photon induced quantum yield regeneration of cap-exchanged CdSe/CdS quantum rods for ratiometric biosensing and cellular imaging.
Biosensing Techniques
/ methods
Biotin
/ chemistry
Cadmium Compounds
/ chemistry
Cell Line, Tumor
Fluorescence Resonance Energy Transfer
Humans
Ligands
Light
Microscopy, Fluorescence
/ methods
Photons
Quantum Dots
/ chemistry
Selenium Compounds
/ chemistry
Small Ubiquitin-Related Modifier Proteins
/ chemistry
Sulfides
/ chemistry
Thioctic Acid
/ analogs & derivatives
Ultraviolet Rays
Journal
Nanoscale
ISSN: 2040-3372
Titre abrégé: Nanoscale
Pays: England
ID NLM: 101525249
Informations de publication
Date de publication:
28 Apr 2020
28 Apr 2020
Historique:
pubmed:
10
3
2020
medline:
15
12
2020
entrez:
10
3
2020
Statut:
ppublish
Résumé
Full water-dispersion of commercial hydrophobic CdSe/CdS core/shell quantum rods (QRs) was achieved by cap-exchange using a dihydrolipoic acid zwitterion ligand at a low ligand:QR molar ratio (LQMR) of 1000. However, this process almost completely quenched the QR fluorescence, greatly limiting its potential in downstream fluorescence based applications. Fortunately, we found that the QR fluorescence could be recovered by exposure to near ultra-violet to blue light radiation (e.g. 300-450 nm). These "reborn" QRs were found to be compact, bright, and stable, and were resistant to non-specific adsorption, which make them powerful fluorescent probes in broad biomedical applications. We demonstrated their potential in two model applications: first, the QRs were conjugated with His
Substances chimiques
Cadmium Compounds
0
Ligands
0
Selenium Compounds
0
Small Ubiquitin-Related Modifier Proteins
0
Sulfides
0
cadmium sulfide
057EZR4Z7Q
Biotin
6SO6U10H04
Thioctic Acid
73Y7P0K73Y
dihydrolipoic acid
7NV2KHU5JA
cadmium selenide
A7F646JC5C
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM