Interval Debulking Surgery for Advanced Ovarian Cancer in Elderly Patients (≥70 y): Does the Age Matter?
CPET
debulking surgery
elderly
morbidity
neoadjuvant chemotherapy
ovarian cancer
Journal
Journal of investigative surgery : the official journal of the Academy of Surgical Research
ISSN: 1521-0553
Titre abrégé: J Invest Surg
Pays: United States
ID NLM: 8809255
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
pubmed:
10
3
2020
medline:
27
8
2021
entrez:
10
3
2020
Statut:
ppublish
Résumé
Elderly ovarian cancer (OC) patients are more likely to be managed suboptimally, with worse clinical outcomes as a result. Strategies to decrease morbidity are lacking. A total of 153 patients were referred during the study period. 114 patients underwent IDS after NACT (74.5%), 46 in Group 1 and 68 in Group 2. Elderly patients were more likely to receive more than three cycles of NACT prior to IDS compared to younger patients (39% vs. 19%, Older age should not preclude clinicians from offering ultra-radical resection to patients with advanced OC after NACT. In our series, elderly patients received the same treatment with similar outcomes to the younger group. Clinicians should be encouraged to use CPET for patients' selection following NACT.
Sections du résumé
BACKGROUND
BACKGROUND
Elderly ovarian cancer (OC) patients are more likely to be managed suboptimally, with worse clinical outcomes as a result. Strategies to decrease morbidity are lacking.
RESULTS
RESULTS
A total of 153 patients were referred during the study period. 114 patients underwent IDS after NACT (74.5%), 46 in Group 1 and 68 in Group 2. Elderly patients were more likely to receive more than three cycles of NACT prior to IDS compared to younger patients (39% vs. 19%,
CONCLUSION
CONCLUSIONS
Older age should not preclude clinicians from offering ultra-radical resection to patients with advanced OC after NACT. In our series, elderly patients received the same treatment with similar outcomes to the younger group. Clinicians should be encouraged to use CPET for patients' selection following NACT.
Identifiants
pubmed: 32148117
doi: 10.1080/08941939.2020.1733146
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1023-1030Commentaires et corrections
Type : CommentIn