Transcriptomic Analysis of Fuzi Lizhong Decoction for the Treatment of Stomach Ulcers.


Journal

Evidence-based complementary and alternative medicine : eCAM
ISSN: 1741-427X
Titre abrégé: Evid Based Complement Alternat Med
Pays: United States
ID NLM: 101215021

Informations de publication

Date de publication:
2020
Historique:
received: 06 11 2019
revised: 31 12 2019
accepted: 17 01 2020
entrez: 10 3 2020
pubmed: 10 3 2020
medline: 10 3 2020
Statut: epublish

Résumé

This study aims to understand the treatment of stomach ulcers with FLD and to identify its potential target genes as well as related pathways by transcriptomic analysis. Rat stomach mRNA from a blank group (BG), a model group (MG), an untreated-model group (u-MG), and a treated group (TG) was sequenced. A partial least-squares discriminant analysis (PLS-DA) was used to differentiate the MG from the BG, and the Deseq2 R Package was used to identify differentially expressed genes between these groups. Furthermore,

Identifiants

pubmed: 32148538
doi: 10.1155/2020/3291853
pmc: PMC7054793
doi:

Types de publication

Journal Article

Langues

eng

Pagination

3291853

Informations de copyright

Copyright © 2020 Yang Xin et al.

Déclaration de conflit d'intérêts

There were no potential conflicts of interests.

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Auteurs

Yang Xin (Y)

College of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar 161006, China.
Heilongjiang Provincial Key Laboratory of Catalytic Synthesis for Fine Chemicals, Qiqihar University, Qiqihar 161006, China.

Haijun Wang (H)

College of Adult and Continuing Education, Qiqihar Medical University, Qiqihar 161006, China.

Lei Xu (L)

College of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar 161006, China.

Classifications MeSH