The origins of the Lacto-Bolo reflex: the mythology of lactate in sepsis.
Sepsis
lactate
metabolic failure
myth
septic shock
the Lacto-Bolo reflex
Journal
Journal of thoracic disease
ISSN: 2072-1439
Titre abrégé: J Thorac Dis
Pays: China
ID NLM: 101533916
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
entrez:
10
3
2020
pubmed:
10
3
2020
medline:
10
3
2020
Statut:
ppublish
Résumé
The use of lactate as a marker of the severity of circulatory shock was popularized by Dr. Weil in the 1970's. Dr. Weil promoted the idea that blood lactate concentration increased in circulatory shock due to anaerobic metabolism following decreased oxygen delivery. This concept becomes entrenched with 1992 ACCP/SCCM consensus conference definition of sepsis. Since then, the central role of lactate in the definition and management of septic shock has only been expanded and become more ingrained. This review will discuss the wisdom of such an approach, an updated model describing the origins of hyperlactatemia in sepsis, and how such improvements in our knowledge of the underlying physiology should change our approach to resuscitation in patients presenting with septic shock.
Identifiants
pubmed: 32148925
doi: 10.21037/jtd.2019.11.48
pii: jtd-12-S1-S48
pmc: PMC7024759
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
S48-S53Informations de copyright
2020 Journal of Thoracic Disease. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of Interest: The authors have no conflicts of interest to declare.
Références
Crit Care Med. 1994 Apr;22(4):640-50
pubmed: 8143474
JAMA. 2010 Feb 24;303(8):739-46
pubmed: 20179283
N Engl J Med. 2011 Jun 30;364(26):2483-95
pubmed: 21615299
JAMA. 2013 Oct 23;310(16):1683-91
pubmed: 24108526
Lancet. 2005 Mar 5-11;365(9462):871-5
pubmed: 15752531
J Intensive Care Med. 2019 Jun 9;:885066619854355
pubmed: 31179840
Shock. 2008 Oct;30(4):417-21
pubmed: 18323749
Shock. 2018 Aug;50(2):162-166
pubmed: 29117063
Chest. 1992 Jun;101(6):1644-55
pubmed: 1303622
Ann Emerg Med. 2005 May;45(5):524-8
pubmed: 15855951
Crit Care Med. 2001 Jul;29(7):1343-9
pubmed: 11445683
Crit Care Med. 2008 Jan;36(1):296-327
pubmed: 18158437
Crit Care Med. 2004 Aug;32(8):1637-42
pubmed: 15286537
Crit Care Med. 2017 Mar;45(3):486-552
pubmed: 28098591
Am J Respir Crit Care Med. 2019 Sep 1;200(5):582-589
pubmed: 30985210
Intensive Care Med. 2007 Jun;33(6):970-7
pubmed: 17431582
West J Emerg Med. 2015 Dec;16(7):1118-26
pubmed: 26759665
Intensive Care Med. 2016 Nov;42(11):1695-1705
pubmed: 27686349
Crit Care Med. 2018 Jun;46(6):997-1000
pubmed: 29767636
Circulation. 1970 Jun;41(6):989-1001
pubmed: 5482913
Lancet. 2002 Jul 20;360(9328):219-23
pubmed: 12133657
Crit Care Med. 2003 Apr;31(4):1250-6
pubmed: 12682500
Intensive Care Med. 2015 Oct;41(10):1862-3
pubmed: 26154408
JAMA. 2017 Oct 3;318(13):1233-1240
pubmed: 28973227
Chest. 2017 Jun;151(6):1229-1238
pubmed: 27940189
Am J Med. 1961 Jun;30:840-8
pubmed: 13716482
Shock. 2015 Jan;43(1):55-61
pubmed: 25186838
Intensive Care Med. 2014 Mar;40(3):412-21
pubmed: 24477453
Chest. 2014 Jan;145(1):53-59
pubmed: 23949578
JAMA. 2019 Feb 19;321(7):654-664
pubmed: 30772908
Crit Care Med. 2013 Feb;41(2):580-637
pubmed: 23353941
Crit Care Med. 2004 Mar;32(3):858-73
pubmed: 15090974
Shock. 2010 Jul;34(1):4-9
pubmed: 20016405
Crit Care. 2014 Sep 09;18(5):503
pubmed: 25394679
N Engl J Med. 2014 Dec 11;371(24):2309-19
pubmed: 25494270
Ann Am Thorac Soc. 2015 Nov;12(11):1662-6
pubmed: 26356483
Anaesth Intensive Care. 2012 May;40(3):427-32
pubmed: 22577907
Crit Care Med. 1988 Jul;16(7):655-8
pubmed: 3371040
Intensive Care Med. 2007 Mar;33(3):495-502
pubmed: 17242933
Am J Respir Crit Care Med. 2010 Sep 15;182(6):752-61
pubmed: 20463176