The Role of the Gut Microbiota in Dietary Interventions for Depression and Anxiety.
anxiety
depression
diet
mental health
microbiome–gut–brain axis
microbiota
mood
nutrition
nutritional psychiatry
Journal
Advances in nutrition (Bethesda, Md.)
ISSN: 2156-5376
Titre abrégé: Adv Nutr
Pays: United States
ID NLM: 101540874
Informations de publication
Date de publication:
01 07 2020
01 07 2020
Historique:
received:
19
03
2019
revised:
16
12
2019
accepted:
17
02
2020
pubmed:
10
3
2020
medline:
28
4
2021
entrez:
10
3
2020
Statut:
ppublish
Résumé
There is emerging evidence that an unhealthy dietary pattern may increase the risk of developing depression or anxiety, whereas a healthy dietary pattern may decrease it. This nascent research suggests that dietary interventions could help prevent, or be an alternative or adjunct therapy for, depression and anxiety. The relation, however, is complex, affected by many confounding variables, and is also likely to be bidirectional, with dietary choices being affected by stress and depression. This complexity is reflected in the data, with sometimes conflicting results among studies. As the research evolves, all characteristics of the relation need to be considered to ensure that we obtain a full understanding, which can potentially be translated into clinical practice. A parallel and fast-growing body of research shows that the gut microbiota is linked with the brain in a bidirectional relation, commonly termed the microbiome-gut-brain axis. Preclinical evidence suggests that this axis plays a key role in the regulation of brain function and behavior. In this review we discuss possible reasons for the conflicting results in diet-mood research, and present examples of areas of the diet-mood relation in which the gut microbiota is likely to be involved, potentially explaining some of the conflicting results from diet and depression studies. We argue that because diet is one of the most significant factors that affects human gut microbiota structure and function, nutritional intervention studies need to consider the gut microbiota as an essential piece of the puzzle.
Identifiants
pubmed: 32149335
pii: S2161-8313(22)00316-7
doi: 10.1093/advances/nmaa016
pmc: PMC7360462
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
890-907Informations de copyright
Copyright © The Author(s) 2020.
Références
J Nutr Biochem. 2019 Mar;65:54-65
pubmed: 30623851
Microbiology (Reading). 2017 Aug;163(8):1145-1147
pubmed: 28809155
J Nutr. 2012 Feb;142(2):271-7
pubmed: 22190022
Appetite. 2015 Dec;95:89-95
pubmed: 26122754
J Clin Psychiatry. 1995 Aug;56(8):363-7
pubmed: 7635853
Physiol Behav. 1998 Aug;65(1):63-8
pubmed: 9811366
Clin Nutr. 2019 Apr;38(2):522-528
pubmed: 29731182
Psychoneuroendocrinology. 2012 Nov;37(11):1885-95
pubmed: 22541937
Hum Psychopharmacol. 2004 Oct;19(7):477-88
pubmed: 15378677
J Affect Disord. 1998 Mar;48(2-3):149-55
pubmed: 9543204
Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16050-5
pubmed: 21876150
Biol Psychiatry. 2015 Apr 1;77(7):607-15
pubmed: 25173628
Nature. 2012 Jun 13;486(7402):207-14
pubmed: 22699609
Biotechnol Adv. 2017 Jan - Feb;35(1):31-40
pubmed: 27890703
BMC Complement Altern Med. 2014 Jun 26;14:204
pubmed: 24969102
Arch Biochem Biophys. 2012 Nov 15;527(2):105-12
pubmed: 22663919
Br J Nutr. 2013 Jun;109(11):2059-66
pubmed: 23051591
PLoS One. 2015 Oct 01;10(10):e0139721
pubmed: 26426902
Diabetes. 2008 Jun;57(6):1470-81
pubmed: 18305141
Nutr Res Pract. 2017 Feb;11(1):25-32
pubmed: 28194262
Eur J Nutr. 2014 Jun;53(4):1051-64
pubmed: 24173964
Am J Clin Nutr. 1980 Feb;33(2):303-23
pubmed: 6766657
Nutrition. 2016 Apr;32(4):491-7
pubmed: 26740253
Lipids. 1996 Mar;31 Suppl:S157-61
pubmed: 8729112
Mol Cell Endocrinol. 2017 Sep 15;453:79-87
pubmed: 27913273
Psychoneuroendocrinology. 2015 Mar;53:233-45
pubmed: 25638481
Neurogastroenterol Motil. 2014 Aug;26(8):1155-62
pubmed: 24888394
Int J Food Microbiol. 2009 Jul 31;133(1-2):1-7
pubmed: 19467724
PLoS One. 2012;7(10):e46231
pubmed: 23056268
Prostaglandins Leukot Essent Fatty Acids. 2017 Dec;127:32-39
pubmed: 29156156
Neurogastroenterol Motil. 2013 Sep;25(9):733-e575
pubmed: 23773726
Proc Nutr Soc. 2010 Aug;69(3):333-40
pubmed: 20515519
Physiol Behav. 1996 Sep;60(3):1039-42
pubmed: 8873290
J Neurosci. 2006 Dec 6;26(49):12664-71
pubmed: 17151269
Brain Behav Immun. 2015 Aug;48:165-73
pubmed: 25866195
J Nutr. 2017 May;147(5):770-780
pubmed: 28356436
J Psychosom Res. 2013 Feb;74(2):142-8
pubmed: 23332529
Gut. 2018 Nov;67(11):1974-1983
pubmed: 28951525
Psychosom Med. 2018 May;80(4):361-369
pubmed: 29533327
Front Microbiol. 2017 Jun 30;8:1226
pubmed: 28713353
Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4485-93
pubmed: 25288760
Br J Nutr. 2011 Mar;105(5):755-64
pubmed: 20974015
Med Hypotheses. 1998 Sep;51(3):267-8
pubmed: 9792205
Am J Clin Nutr. 2014 Jan;99(1):181-97
pubmed: 24196402
Scand J Gastroenterol. 2002 Mar;37(3):294-8
pubmed: 11916191
Science. 1984 Dec 14;226(4680):1342-4
pubmed: 6334362
Neurosci Biobehav Rev. 2013 Dec;37(10 Pt 1):2331-71
pubmed: 23261405
J Nutr Biochem. 2018 Dec;62:35-42
pubmed: 30245181
Sci Rep. 2015 Jun 11;5:11276
pubmed: 26062993
Br J Nutr. 2010 Sep;104(6):919-29
pubmed: 20441670
J Psychiatr Res. 2016 Nov;82:109-18
pubmed: 27491067
Neuroscience. 2015 Dec 3;310:561-77
pubmed: 26408987
Ann Gen Psychiatry. 2012 Sep 24;11(1):24
pubmed: 23006931
Psychol Bull. 1995 Mar;117(2):285-305
pubmed: 7724692
Eur J Nutr. 2016 Jun;55(4):1479-89
pubmed: 26130323
Psychol Med. 2014 Aug;44(11):2363-74
pubmed: 24451993
Brain Behav Immun. 2015 Aug;48:186-94
pubmed: 25882912
J Psychiatr Res. 2018 Sep;104:130-136
pubmed: 30029052
J Clin Psychiatry. 2001;62 Suppl 8:38-45; discussion 46-7
pubmed: 12108820
J Affect Disord. 2004 Nov 1;82(3):447-52
pubmed: 15555697
Nature. 2008 Oct 16;455(7215):894-902
pubmed: 18923511
Can J Psychiatry. 2015 Oct;60(10):460-3
pubmed: 26720193
Br J Psychiatry. 2009 Nov;195(5):408-13
pubmed: 19880930
Acta Psychiatr Scand. 2016 Aug;134(2):150-60
pubmed: 27238642
Cell Mol Gastroenterol Hepatol. 2019;7(2):457-473
pubmed: 30765332
Prostaglandins Leukot Essent Fatty Acids. 2005 Mar;72(3):211-8
pubmed: 15664306
Int J Obes (Lond). 2013 Feb;37(2):216-23
pubmed: 22410962
Lancet. 1998 Apr 18;351(9110):1213
pubmed: 9643729
Sci Rep. 2017 Mar 07;7:43859
pubmed: 28266612
Psychosom Med. 2007 Apr;69(3):217-24
pubmed: 17401057
J Clin Biochem Nutr. 2016 Sep;59(2):113-121
pubmed: 27698538
Br J Nutr. 2012 Oct;108(7):1143-9
pubmed: 22313665
Public Health Nutr. 2015 Aug;18(11):2074-93
pubmed: 25465596
J Epidemiol Community Health. 2001 Oct;55(10):716-20
pubmed: 11553654
Dig Dis Sci. 2004 Apr;49(4):579-89
pubmed: 15185861
Pharmacol Res. 2013 Mar;69(1):52-60
pubmed: 23147033
Biol Psychiatry. 2009 May 1;65(9):732-41
pubmed: 19150053
Gastroenterology. 2010 Dec;139(6):2102-2112.e1
pubmed: 20600016
Bioessays. 2011 Aug;33(8):574-81
pubmed: 21732396
J Affect Disord. 2013 Sep 5;150(2):490-8
pubmed: 23759276
Food Nutr Res. 2016 Apr 27;60:29993
pubmed: 27125264
J Nutr Biochem. 2016 May;31:150-65
pubmed: 27133434
Mol Psychiatry. 2016 Jun;21(6):786-96
pubmed: 27067014
Mol Psychiatry. 2007 Apr;12(4):331-59
pubmed: 17389902
Mol Psychiatry. 2017 May;22(5):733-744
pubmed: 27595593
J Neural Transm Gen Sect. 1995;102(2):91-7
pubmed: 8748674
Neuropsychiatr Dis Treat. 2011;7(Suppl 1):3-7
pubmed: 21750622
J Neuroinflammation. 2011 Aug 10;8:94
pubmed: 21831269
Nature. 2014 Jan 23;505(7484):559-63
pubmed: 24336217
PLoS One. 2012;7(12):e51593
pubmed: 23251585
Am J Physiol Gastrointest Liver Physiol. 2014 Oct 15;307(8):G793-802
pubmed: 25190473
Eur J Clin Nutr. 2010 Aug;64(8):832-9
pubmed: 20485303
Prog Neuropsychopharmacol Biol Psychiatry. 2011 Apr 29;35(3):676-92
pubmed: 20471444
Am J Psychiatry. 1999 Jun;156(6):837-41
pubmed: 10360120
Prev Sci. 2011 Dec;12(4):361-71
pubmed: 21732121
Mol Psychiatry. 2013 Jun;18(6):666-73
pubmed: 22688187
J Affect Disord. 2007 Feb;98(1-2):143-51
pubmed: 16952400
Nutrients. 2018 May 09;10(5):
pubmed: 29747386
Am J Physiol Regul Integr Comp Physiol. 2003 May;284(5):R1269-76
pubmed: 12676748
Br J Psychiatry. 2009 Oct;195(4):301-7
pubmed: 19794197
J Dig Dis. 2018 Apr;19(4):225-234
pubmed: 29573237
Gastroenterology. 2009 Nov;137(5):1716-24.e1-2
pubmed: 19706296
Physiol Behav. 2006 Oct 30;89(3):350-7
pubmed: 16887154
J Psychiatr Res. 2008 Dec;43(2):164-74
pubmed: 18456279
Drugs Today (Barc). 2013 Dec;49(12):791-8
pubmed: 24524097
J Affect Disord. 2012 Dec 1;141(1):79-85
pubmed: 22397891
Int J Obes (Lond). 2019 Apr;43(4):862-871
pubmed: 30206336
J Affect Disord. 2006 Feb;90(2-3):131-9
pubmed: 16325262
Curr Psychiatry Rep. 2011 Dec;13(6):467-75
pubmed: 21927805
Nat Commun. 2014 May 20;5:3889
pubmed: 24846660
J Agric Food Chem. 2017 Jan 25;65(3):586-595
pubmed: 28029051
Neurogastroenterol Motil. 2011 Dec;23(12):1132-9
pubmed: 21988661
Behav Res Ther. 1982;20(2):113-21
pubmed: 7073642
Biol Psychiatry. 1998 Mar 1;43(5):315-9
pubmed: 9513745
Appetite. 2009 Oct;53(2):245-8
pubmed: 19505515
Br J Psychiatry. 2013 Feb;202:100-7
pubmed: 23377209
PLoS One. 2017 Nov 9;12(11):e0188011
pubmed: 29121673
FEMS Microbiol Rev. 2014 Nov;38(6):1202-34
pubmed: 25205464
Prog Neuropsychopharmacol Biol Psychiatry. 2007 Oct 1;31(7):1393-6
pubmed: 17659823
Brain Behav Immun. 2011 Mar;25(3):397-407
pubmed: 21040780
J Psychopharmacol. 2013 May;27(5):451-8
pubmed: 23364814
Prog Neuropsychopharmacol Biol Psychiatry. 2016 Nov 3;71:76-82
pubmed: 27346743
Am J Clin Nutr. 2010 Mar;91(3):757-70
pubmed: 20130098
Sci Rep. 2019 Jan 17;9(1):172
pubmed: 30655577
Klin Wochenschr. 1990 Jan 19;68(2):142-5
pubmed: 2157087
ISRN Gastroenterol. 2013 Apr 04;2013:630159
pubmed: 23691339
J Affect Disord. 2013 Jan 10;144(1-2):165-70
pubmed: 22840609
Physiol Behav. 2017 Oct 15;180:70-77
pubmed: 28821445
J Nutr. 1977 Sep;107(9):1707-14
pubmed: 894368
Appetite. 2013 Nov;70:53-9
pubmed: 23831151
Nutrients. 2017 Feb 20;9(2):
pubmed: 28230732
PLoS One. 2014 Oct 09;9(10):e109606
pubmed: 25299601
J Neurosci. 2015 Jul 29;35(30):10821-30
pubmed: 26224864
Biol Psychiatry. 2017 Oct 1;82(7):472-487
pubmed: 28242013
Biomed Res Int. 2015;2015:850902
pubmed: 25793210
Eur J Cancer Prev. 1997 Mar;6 Suppl 1:S43-5
pubmed: 9167138
Psychophysiology. 2002 Nov;39(6):861-4
pubmed: 12462513
Nutrients. 2014 Apr 11;6(4):1501-18
pubmed: 24732019
Am J Clin Nutr. 2013 Sep;98(3):813-20
pubmed: 23885043
Eur J Clin Nutr. 2016 Mar;70(3):380-5
pubmed: 26648330
Nat Neurosci. 2015 Jul;18(7):965-77
pubmed: 26030851
FASEB J. 2015 Apr;29(4):1395-403
pubmed: 25550456
J Affect Disord. 2014 Apr;159:1-6
pubmed: 24679382
Trends Immunol. 2006 Jan;27(1):24-31
pubmed: 16316783
Psychoneuroendocrinology. 2005 Oct;30(9):846-56
pubmed: 15961250
Nature. 2009 Oct 29;461(7268):1282-6
pubmed: 19865172
Eur J Clin Nutr. 2013 Jan;67(1):75-82
pubmed: 23212131
Int J Obes (Lond). 2013 Mar;37(3):382-9
pubmed: 22508336
Nutr Neurosci. 2019 Jun;22(6):425-434
pubmed: 29173065
Am J Clin Nutr. 2008 Nov;88(5):1438-46
pubmed: 18996881
Psychoneuroendocrinology. 2014 Apr;42:207-17
pubmed: 24636517
Cerebrum. 2016 Jul 01;2016:
pubmed: 28058091
J Affect Disord. 2016 Sep 15;202:254-7
pubmed: 27288567
Nutr Neurosci. 2021 Jun;24(6):490-499
pubmed: 31379269
Psychol Med. 2006 Dec;36(12):1727-35
pubmed: 16938145
Nutrition. 2011 May;27(5):530-3
pubmed: 20688474
Molecules. 2018 Aug 30;23(9):
pubmed: 30200213
PLoS One. 2013 Jun 05;8(6):e65006
pubmed: 23755167
Mol Nutr Food Res. 2014 Sep;58(9):1883-96
pubmed: 24990219
Eur J Clin Nutr. 2007 Mar;61(3):355-61
pubmed: 17151594
Nat Microbiol. 2019 Apr;4(4):623-632
pubmed: 30718848
Neurogastroenterol Motil. 2013 Jun;25(6):521-8
pubmed: 23480302
Eur J Neurosci. 2017 Feb;45(3):342-357
pubmed: 27763700
Gastroenterology. 2011 Aug;141(2):599-609, 609.e1-3
pubmed: 21683077
Prikl Biokhim Mikrobiol. 2006 May-Jun;42(3):261-8
pubmed: 16878539
Psychiatr Serv. 2001 Apr;52(4):529-31
pubmed: 11274502
Acta Neuropsychiatr. 2015 Jun;27(3):168-76
pubmed: 25690713
Cell Host Microbe. 2015 May 13;17(5):681-9
pubmed: 25891358
Physiol Behav. 2009 Dec 7;98(5):563-9
pubmed: 19751751
J Neuroimmunol. 2008 Dec 15;205(1-2):44-50
pubmed: 18954912
J Nutr. 2012 Aug;142(8):1510-8
pubmed: 22739368
Brain Behav Immun. 2014 Feb;36:46-53
pubmed: 24095894
Cell. 2015 Apr 9;161(2):264-76
pubmed: 25860609
Am J Psychiatry. 2010 Mar;167(3):305-11
pubmed: 20048020
Neurochem Int. 2016 Oct;99:110-132
pubmed: 27346602
Public Health Nutr. 2011 Sep;14(9):1663-70
pubmed: 21477412
Environ Microbiol Rep. 2013 Oct;5(5):765-75
pubmed: 24115628
J Nutr Biochem. 2014 Sep;25(9):893-902
pubmed: 24917046
J Neurol Neurosurg Psychiatry. 2000 Aug;69(2):228-32
pubmed: 10896698
Nat Rev Gastroenterol Hepatol. 2017 Aug;14(8):491-502
pubmed: 28611480
Neurosci Lett. 2005 Dec 2;389(2):109-14
pubmed: 16118039
Curr Opin Behav Sci. 2017 Apr;14:1-8
pubmed: 27812532
Int J Obes (Lond). 2016 Jun;40(6):1039-42
pubmed: 26876435
PLoS One. 2014 May 07;9(5):e96905
pubmed: 24805797
World J Gastroenterol. 2002 Jun;8(3):540-5
pubmed: 12046088
J Nutr Health Aging. 2010 Jun;14(6):449-55
pubmed: 20617287
Neuropharmacology. 2008 Mar;54(3):530-41
pubmed: 18164735
Brain Behav Immun. 2017 Jan;59:21-37
pubmed: 27423492
PLoS One. 2016 Jan 08;11(1):e0146406
pubmed: 26745269
Behav Brain Res. 2014 Jul 15;268:1-7
pubmed: 24717328
J Endocrinol. 1999 Jan;160(1):1-12
pubmed: 9854171
J Bone Miner Res. 2012 Jun;27(6):1357-67
pubmed: 22407806
Sci Transl Med. 2009 Nov 11;1(6):6ra14
pubmed: 20368178
PLoS One. 2014 Aug 18;9(8):e103398
pubmed: 25133574
Gut Microbes. 2014;5(6):748-60
pubmed: 25536463
Curr Opin Biotechnol. 2013 Apr;24(2):160-8
pubmed: 22940212
J Nutr Biochem. 2009 Jan;20(1):70-7
pubmed: 18495461
Am J Psychiatry. 2004 Nov;161(11):1957-66
pubmed: 15514393
Scand J Gastroenterol. 1997 Oct;32(10):1013-21
pubmed: 9361174
ISME J. 2014 Feb;8(2):295-308
pubmed: 24030595
Neuroscience. 2010 Nov 10;170(4):1179-88
pubmed: 20696216
Psychosom Med. 2011 Jul-Aug;73(6):483-90
pubmed: 21715296
Cell Physiol Biochem. 2015;37(3):1029-43
pubmed: 26402520
mSphere. 2018 Aug 29;3(4):
pubmed: 30158281
Mol Neurodegener. 2014 Sep 13;9:36
pubmed: 25217888
Psychopharmacology (Berl). 2015 May;232(10):1793-801
pubmed: 25449699
Biochim Biophys Acta. 2014 Jun;1838(6):1518-28
pubmed: 24388951
J Neurochem. 2007 May;101(3):577-99
pubmed: 17257165
Mol Psychiatry. 2007 Nov;12(11):988-1000
pubmed: 17457312
BMC Med. 2013 Jan 03;11:3
pubmed: 23286788
CNS Spectr. 2016 Apr;21(2):184-98
pubmed: 26307347
Free Radic Biol Med. 2013 Oct;63:187-94
pubmed: 23707456
Gut. 2015 Jan;64(1):93-100
pubmed: 25016597
Yonsei Med J. 2017 Nov;58(6):1083-1091
pubmed: 29047231
Nutr Rev. 1997 May;55(5):145-9
pubmed: 9212690
Nature. 2015 Mar 5;519(7541):92-6
pubmed: 25731162
Am J Public Health. 2014 Oct;104(10):e31-42
pubmed: 25208008
Neurogastroenterol Motil. 2011 Mar;23(3):255-64, e119
pubmed: 21054680
J Physiol. 2004 Jul 1;558(Pt 1):263-75
pubmed: 15133062
Can J Psychiatry. 2006 Feb;51(2):100-13
pubmed: 16989109
Am J Clin Nutr. 2009 Jul;90(1):149-55
pubmed: 19474139
Scand J Immunol. 2014 Oct;80(4):250-60
pubmed: 24965690
Am J Physiol Cell Physiol. 2016 Sep 1;311(3):C386-91
pubmed: 27413170
Arch Psychiatr Nervenkr (1970). 1982;232(4):299-304
pubmed: 6133511
Immunity. 2014 Jan 16;40(1):128-39
pubmed: 24412617
J Cardiovasc Pharmacol Ther. 2015 May;20(3):289-98
pubmed: 25331262
Nat Commun. 2017 Apr 04;8:15062
pubmed: 28375200
Infect Immun. 1974 Mar;9(3):591-8
pubmed: 4593471
Mol Psychiatry. 2009 May;14(5):511-22
pubmed: 18195714
Gut Pathog. 2009 Mar 19;1(1):6
pubmed: 19338686
Br J Nutr. 2017 Jun;117(12):1645-1655
pubmed: 28789729
Am J Clin Nutr. 2011 Jun;93(6):1337-43
pubmed: 21471279
J Trauma. 2006 Sep;61(3):650-7
pubmed: 16967002
J Psychopharmacol. 2005 Jan;19(1):59-65
pubmed: 15671130
Ann N Y Acad Sci. 1995 Dec 29;771:55-72
pubmed: 8597429
J Affect Disord. 2018 Jan 15;226:346-354
pubmed: 29031185
Nat Rev Neurosci. 2008 Oct;9(10):788-96
pubmed: 18784657
Biol Psychiatry. 2009 Feb 1;65(3):263-7
pubmed: 18723164
Acta Psychiatr Scand. 2017 May;135(5):373-387
pubmed: 28122130
Biomed Pharmacother. 2017 Feb;86:414-425
pubmed: 28012396
Mol Nutr Food Res. 2011 May;55 Suppl 1:S44-55
pubmed: 21294250
Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):3047-52
pubmed: 21282636
Brain Behav Immun. 2017 Mar;61:50-59
pubmed: 27865949