18F-FDG Uptake in a T2 Hypointense Paraspinal Mass.

Aged Amyloidosis / complications Biological Transport Fluorodeoxyglucose F18 / metabolism Humans Incidental Findings Lymphoma / complications Magnetic Resonance Imaging Male Positron Emission Tomography Computed Tomography Spine / diagnostic imaging

Journal

Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109

Informations de publication

Date de publication:
May 2020
Historique:
pubmed: 10 3 2020
medline: 28 8 2020
entrez: 10 3 2020
Statut: ppublish

Résumé

We present a paraspinal amyloidoma found incidentally in a 77-year-old man during lymphoma workup by F-FDG PET/CT. A solitary FDG-avid paraspinal lesion was seen at T11-T12. MRI showed T2 hypointensity and enhancement. Lymphoma was considered the primary differential due to FDG uptake, but biopsy revealed nodules of extracellular acellular homogeneous material with apple-green birefringence on Congo red stain consistent with amyloidoma. Spinal amyloidoma is rare with few cases reported so far in literature.

Identifiants

DOI: 10.1097/RLU.0000000000002976 PMID: 32149807
pubmed: 32149807
doi: 10.1097/RLU.0000000000002976
pii: 00003072-202005000-00012
doi:

Substances chimiques

Fluorodeoxyglucose F18 0Z5B2CJX4D

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

385-386

Références

Georgiades CS, Neyman EG, Barish MA, et al. Amyloidosis: review and CT manifestations. Radiographics. 2004;24:405–416.
Parmar H, Rath T, Castillo M, et al. Imaging of focal amyloid depositions in the head, neck, and spine: amyloidoma. AJNR Am J Neuroradiol. 2010;31:1165–1170.
Mizuno J, Nakagawa H, Tsuji Y, et al. Primary amyloidoma of the thoracic spine presenting with acute paraplegia. Surg Neurol. 2001;55:378–382.
Iplikcioglu AC, Bek S, Gokduman CA, et al. Primary solitary cervical amyloidosis: case report and review of the literature. Spine (Phila Pa 1976). 2007;32:E45–E47.
Unal A, Sutlap PN, Kyyyk M. Primary solitary amyloidoma of thoracic spine: a case report and review of the literature. Clin Neurol Neurosurg. 2003;105:167–169.
Dickman CA, Sonntag VK, Johnson P, et al. Amyloidoma of the cervical spine: a case report. Neurosurgery. 1988;22:419–422.
Aono H, Kakunaga S, Koide S, et al. Primary amyloidoma in epidural and paravertebral space of the lumbar spine. Spine J. 2013;13:e27–e30.
Glaudemans AW, Slart RH, Noordzij W, et al. Utility of 18F-FDG PET(/CT) in patients with systemic and localized amyloidosis. Eur J Nucl Med Mol Imaging. 2013;40:1095–1101.
Ran P, Liu Y, Liang X, et al. FDG PET/CT in a case of dural amyloidoma. Clin Nucl Med. 2018;43:925–929.

Auteurs

Aparna Singhal (A)

From the Section of Neuroradiology, Department of Radiology.

Narendra Adhikari (N)

From the Section of Neuroradiology, Department of Radiology.

Diego A de Idiaquez Bakula (DA)

Division of Hematology-Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.

Houman Sotoudeh (H)

From the Section of Neuroradiology, Department of Radiology.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › 18F-FDG Uptake in a T2 Hypointense Paraspinal Mass.
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Troubles de l'homéostasie des protéines › Amyloïdose › 18F-FDG Uptake in a T2 Hypointense Paraspinal Mass.
questionsmedicales.fr › Métabolisme › Transport biologique › 18F-FDG Uptake in a T2 Hypointense Paraspinal Mass.
questionsmedicales.fr › Glucides › Désoses › Désoxyglucose › Fluorodésoxyglucose F18 › 18F-FDG Uptake in a T2 Hypointense Paraspinal Mass.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › 18F-FDG Uptake in a T2 Hypointense Paraspinal Mass.
questionsmedicales.fr › Diagnostic › Résultats fortuits › 18F-FDG Uptake in a T2 Hypointense Paraspinal Mass.
questionsmedicales.fr › Maladies du système immunitaire › Syndromes immunoprolifératifs › Syndromes lymphoprolifératifs › Lymphomes › 18F-FDG Uptake in a T2 Hypointense Paraspinal Mass.
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › 18F-FDG Uptake in a T2 Hypointense Paraspinal Mass.
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Tomographie par émission de positons couplée à la tomodensitométrie › 18F-FDG Uptake in a T2 Hypointense Paraspinal Mass.
questionsmedicales.fr › Appareil locomoteur › Squelette › Rachis › 18F-FDG Uptake in a T2 Hypointense Paraspinal Mass.