ARGONAUT II Study of the

Adult Aged Anti-Bacterial Agents / pharmacology Bacterial Proteins / metabolism Carbapenem-Resistant Enterobacteriaceae / drug effects Drug Resistance, Bacterial / genetics Female Humans Klebsiella pneumoniae / drug effects Male Methyltransferases / genetics Microbial Sensitivity Tests Middle Aged Sisomicin / analogs & derivatives United States beta-Lactamases / metabolism
Klebsiella antibiotic resistance carbapenemase plazomicin

Journal

Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061

Informations de publication

Date de publication:
21 04 2020
Historique:
received: 07 01 2020
accepted: 02 03 2020
pubmed: 11 3 2020
medline: 10 4 2021
entrez: 11 3 2020
Statut: epublish

Résumé

Plazomicin was tested against 697 recently acquired carbapenem-resistant

Identifiants

DOI: 10.1128/AAC.00012-20 PMID: 32152078 PMC: PMC7179617
pubmed: 32152078
pii: AAC.00012-20
doi: 10.1128/AAC.00012-20
pmc: PMC7179617
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Bacterial Proteins 0
Methyltransferases EC 2.1.1.-
beta-Lactamases EC 3.5.2.6
carbapenemase EC 3.5.2.6
plazomicin LYO9XZ250J
Sisomicin X55XSL74YQ

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI100560
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI143229
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI072219
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI063517
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI110819
Pays : United States
Organisme : BLRD VA
ID : I01 BX001974
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI090155
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI134637
Pays : United States
Organisme : NIAID NIH HHS
ID : UM1 AI104681
Pays : United States

Informations de copyright

Copyright © 2020 American Society for Microbiology.

Références

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pubmed: 29444952
Int J Infect Dis. 2016 Feb;43:17-20
pubmed: 26686939
Clin Infect Dis. 2020 Feb 3;70(4):704-709
pubmed: 31328228
BMC Infect Dis. 2019 Feb 15;19(1):167
pubmed: 30770727
Int J Antimicrob Agents. 2018 Aug;52(2):278-282
pubmed: 29596903
Infect Dis Clin North Am. 2016 Jun;30(2):523-537
pubmed: 27208771
J Antimicrob Chemother. 2018 Dec 1;73(12):3346-3354
pubmed: 30219857
Open Forum Infect Dis. 2019 Mar 12;6(4):ofz123
pubmed: 30968059
Antimicrob Agents Chemother. 2020 Jan 27;64(2):
pubmed: 31712206
Diagn Microbiol Infect Dis. 2019 May;94(1):73-77
pubmed: 30661726
Antimicrob Agents Chemother. 2018 Dec 21;63(1):
pubmed: 30323050
Antimicrob Agents Chemother. 2017 Jun 27;61(7):
pubmed: 28461314
Pharmacotherapy. 2019 Jan;39(1):77-93
pubmed: 30511766
J Antimicrob Chemother. 2018 Mar 1;73(3):821-823
pubmed: 29194479

Auteurs

Michael R Jacobs (MR)

Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA mrj6@case.edu robert.bonomo@va.gov.
Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

Caryn E Good (CE)

Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.
Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

Andrea M Hujer (AM)

Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.

Ayman M Abdelhamed (AM)

Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.
Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

Daniel D Rhoads (DD)

Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA.
Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

Kristine M Hujer (KM)

Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.

Susan D Rudin (SD)

Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.

T Nicholas Domitrovic (TN)

Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.

Lynn E Connolly (LE)

Achaogen, Inc., South San Francisco, California, USA.

Kevin M Krause (KM)

Achaogen, Inc., South San Francisco, California, USA.

Robin Patel (R)

Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
ORCID: 0000-0001-6344-4141

Cesar A Arias (CA)

Division of Infectious Diseases, McGovern School of Medicine at Houston, Houston, Texas, USA.
Center for Antimicrobial Resistance and Microbial Genomics, McGovern School of Medicine at Houston, Houston, Texas, USA.
Center for Infectious Diseases, UTHealth School of Public Health, Houston, Texas, USA.
Molecular Genetics and Antimicrobial Resistance Unit, International Center for Microbial Genomics, Universidad El Bosque, Bogota, Colombia.

Barry N Kreiswirth (BN)

Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, USA.

Laura J Rojas (LJ)

Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.

Roshan D'Souza (R)

J. Craig Venter Institute, Rockville, Maryland, USA.

Richard C White (RC)

J. Craig Venter Institute, Rockville, Maryland, USA.

Lauren M Brinkac (LM)

J. Craig Venter Institute, Rockville, Maryland, USA.

Kevin Nguyen (K)

J. Craig Venter Institute, Rockville, Maryland, USA.

Indresh Singh (I)

J. Craig Venter Institute, Rockville, Maryland, USA.

Derrick E Fouts (DE)

J. Craig Venter Institute, Rockville, Maryland, USA.
ORCID: 0000-0003-4323-7668

David van Duin (D)

Division of Infectious Diseases, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
ORCID: 0000-0003-4784-3227

Robert A Bonomo (RA)

Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA mrj6@case.edu robert.bonomo@va.gov.
Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.
Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio, USA.
Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA.
Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, USA.
Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, USA.
CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology, Cleveland, Ohio, USA.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › ARGONAUT II Study of the
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › ARGONAUT II Study of the
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › ARGONAUT II Study of the
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › ARGONAUT II Study of the
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Enterobacteriaceae résistantes aux carbapénèmes › ARGONAUT II Study of the
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Résistance microbienne aux médicaments › Résistance bactérienne aux médicaments › ARGONAUT II Study of the
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › ARGONAUT II Study of the
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Klebsiella › Klebsiella pneumoniae › ARGONAUT II Study of the
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › One-carbon group transferases › Methyltransferases › ARGONAUT II Study of the
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › ARGONAUT II Study of the
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › ARGONAUT II Study of the
questionsmedicales.fr › Glucides › Hétérosides › Aminosides › Gentamicine › Sisomicine › ARGONAUT II Study of the
questionsmedicales.fr › Régions géographiques › Amériques › Amérique du Nord › États-Unis › ARGONAUT II Study of the
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Amidohydrolases › bêta-Lactamases › ARGONAUT II Study of the