Safetxt: a safer sex intervention delivered by mobile phone messaging on sexually transmitted infections (STI) among young people in the UK - protocol for a randomised controlled trial.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
08 03 2020
Historique:
entrez: 11 3 2020
pubmed: 11 3 2020
medline: 14 4 2021
Statut: epublish

Résumé

Young people aged 16 to 24 have the highest prevalence of genital chlamydia and gonorrhoea compared with other age groups and re-infection rates following treatment are high. Long-term adverse health effects include subfertility and ectopic pregnancy, particularly among those with repeated infections. We developed the safetxt intervention delivered by text message to reduce sexually transmitted infection (STI) by increasing partner notification, condom use and (STI) testing among young people in the UK. A single-blind randomised trial to reliably establish the effect of the safetxt intervention on chlamydia and gonorrhoea infection at 1 year. We will recruit 6250 people aged 16 to 24 years who have recently been diagnosed with chlamydia, gonorrhoea or non-specific urethritis from health services in the UK. Participants will be allocated to receive the safetxt intervention (text messages designed to promote safer sexual health behaviours) or to receive the control text messages (monthly messages asking participants about changes in contact details) by an automated remote online randomisation system. The primary outcome will be the cumulative incidence of chlamydia and gonorrhoea infection at 1 year assessed by nucleic acid amplification tests. Secondary outcomes include partner notification, correct treatment of infection, condom use and STI testing prior to sex with new partners. Ethics approval was obtained from NHS Health Research Authority - London - Riverside Research Ethics Committee (REC reference: 15/LO/1665) and the London School of Hygiene & Tropical Medicine. We will submit the results of the trial for publication in peer-reviewed journals. International Standard Randomised Controlled Trials Number: ISRCTN64390461. Registered on 17 12, 19

Identifiants

pubmed: 32152156
pii: bmjopen-2019-031635
doi: 10.1136/bmjopen-2019-031635
pmc: PMC7064138
doi:

Banques de données

ISRCTN
['ISRCTN64390461']

Types de publication

Clinical Trial Protocol Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e031635

Subventions

Organisme : Department of Health
ID : 14/182/07
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_12023/21
Pays : United Kingdom
Organisme : Department of Health
ID : PHR/14/182/07
Pays : United Kingdom

Informations de copyright

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Caroline Free (C)

Population Health, London School of Hygiene and Tropical Medicine, London, London, UK caroline.free@lshtm.ac.uk.

Ona L McCarthy (OL)

Population Health, London School of Hygiene and Tropical Medicine, London, London, UK.

Melissa J Palmer (MJ)

Population Health, London School of Hygiene and Tropical Medicine, London, London, UK.

Rosemary Knight (R)

Clinical Trials Unit, MSD, London School of Hygiene and Tropical Medicine, London, London, UK.

Phil Edwards (P)

Population Health, London School of Hygiene and Tropical Medicine, London, London, UK.

Rebecca French (R)

Social and Environmental Health Research, London School of Hygiene and Tropical Medicine, London, London, UK.

Paula Baraitser (P)

Centre for Global Health, King's College London, London, London, UK.

Ford Colin Ian Hickson (FCI)

Sigma Research, London School of Hygiene and Tropical Medicine, London, London, UK.

Kaye Wellings (K)

Social and Environmental Health Research, London School of Hygiene and Tropical Medicine, London, London, UK.

Ian Roberts (I)

Population Health, London School of Hygiene and Tropical Medicine, London, London, UK.

Julia V Bailey (JV)

Primary Care and Population Health, University College London, London, London, UK.

Graham Hart (G)

Department of Infection and Population Health, University College London, London, London, UK.

Susan Michie (S)

Centre for Outcomes Research and Effectivenes, University College London, London, London, UK.

Tim Clayton (T)

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, London, UK.

George B Ploubidis (GB)

Department of Social Science, University College London Institute of Education, London, London, UK.

James R Carpenter (JR)

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, London, UK.

Katy M E Turner (KME)

Bristol Vetinary School, University of Bristol, Bristol, UK.

Karen Devries (K)

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, London, UK.

Kimberley Potter (K)

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, London, UK.

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